Hao Yin @HaoYin@qoto.org
Cardiovascular biologist, Dr. J. Geoffrey Pickering lab, Robarts Research Institute, Western University, London, Ontario, Canada
https://scholar.google.ca/citations?hl=en&user=IbrDx00AAAAJ&view_op
Joined Nov 2022
Arterial dictation of fetal #Hematopoiesis👹
Fetal bone marrow Bmx+ arterial #EndothelialCell (not Myh11+ mural cell) Wnt2->
⏫c-Kit+ HSPC β-catenin signals->
⏫colonization & transplant engraftment
Dr. Ralf Adams lab Nature Commmnications 2022
https://www.nature.com/articles/s41467-022-28775-x
#Introduction Hello, I am a postdoctoral research associate at Robarts Research Institute, Canada.
I have been studying vascular biology, with a specialized focus on Aorta & muscle microvasculature, and broad interests in biomedical & biological sciences.
Currently writing up all viable projects in my generation Hopefully to be on the job market soon.
Nice to meet everyone on Mastodon
Hao Yin
boosted
Hi #ScienceMastodon
I’m a professor of molecular biology at UT Sorhwestern Medical Center. Our lab works on organ development, with a focus on the cardiovascular system, pancreas, kidney and lung. We use mouse models and organoids to ask questions about cell fate. Looking forward to learning and interacting here, as on Twiiter (let’s see how that site develops with the “change in leadership”).
Hao Yin
boosted
Quick question: can we be on multiple servers? Lots of peeps I don’t see because they are on “different servers”. Still getting used to this place…
Hao Yin
boosted
You all are awesome for trying to explain Mastodon to me 💙 but it’s gonna take me a while 😂 (also, why can’t I attach images?) https://twitter.com/cstegman/status/1588923018868592641?s=46&t=m7OF_4G0T1KDQDYyt606gQ
#PROTAB proteolysis-targeting antibody
An evolving #PROTAC variant
Use tumor-enriched cell surface #E3Ligase RNF43/ZNRF3 for targeted degradation of transmembrane proteins IGF1R/HER2/PD-L1
Dr. N. Agard & F. de Sousa e Melo labs @Nature 2022 @genentech
https://www.nature.com/articles/s41586-022-05235-6
Retinal & Choroidal Vasculature in Patients with #MarfanSyndrome
24 case+26 ctrl
#OpticalCoherenceTomography Angiography
⏬(by 3~11%) Microvessel densities in superficial/deep/choriocapillaris plexus
Dr Matteo Di Marino lab Transl Vis Sci Technol 2020
https://tvst.arvojournals.org/article.aspx?articleid=2770566
Retinal arteriopathy in #Marfan🐭
A role of Fibrillin-1 in microvasculature🤠
Arteriolar dilation
Focal #SmoothMuscleCell loss
Leakiness peri-arteriolar albumin
(As early as P6)
Dr Florian Alonso & Elisabeth Génot lab @Biomol_MDPI 2022
https://www.mdpi.com/2218-273X/12/10/1330/htm
Cardiovascular biologist, Dr. J. Geoffrey Pickering lab, Robarts Research Institute, Western University, London, Ontario, Canada
https://scholar.google.ca/citations?hl=en&user=IbrDx00AAAAJ&view_op
Joined Nov 2022
