bioRxiv @biorxivpreprint@qoto.org

The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk https://www.biorxiv.org/content/10.1101/2023.03.14.532553v1?med=mas

A thermodynamic analysis of CLC transporter dimerization in lipid bilayers https://www.biorxiv.org/content/10.1101/2023.03.14.532678v1?med=mas

Development of QSAR Models to Identify Mycobacterium tuberculosis enoyl-ACP-reductase Enzyme Inhibitors https://www.biorxiv.org/content/10.1101/2023.03.13.532463v1?med=mas

What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds https://www.biorxiv.org/content/10.1101/2023.03.14.532539v1?med=mas

FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in-vitro toxicology and pharmacology https://www.biorxiv.org/content/10.1101/2023.03.13.528447v1?med=mas

Protein-specific signal peptides for mammalian vector engineering https://www.biorxiv.org/content/10.1101/2023.03.14.532380v1?med=mas

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies https://www.biorxiv.org/content/10.1101/2023.03.14.532666v1?med=mas

Titering of Chimeric Antigen Receptors on CAR T Cells enabled by a Microfluidic-based Dosage-Controlled Intracellular mRNA Delivery Platform https://www.biorxiv.org/content/10.1101/2023.03.14.532624v1?med=mas

Sulfide oxidation promotes hypoxic angiogenesis and neovascularization https://www.biorxiv.org/content/10.1101/2023.03.14.532677v1?med=mas

Population-level annotation of lncRNAs in Arabidopsis thaliana reveals extensive expression and epigenetic variability associated with TE-like silencing https://www.biorxiv.org/content/10.1101/2023.03.14.532599v1?med=mas

The origin and structural evolution of de novo genes in Drosophila https://www.biorxiv.org/content/10.1101/2023.03.13.532420v1?med=mas

Portable X-ray fluorescence for identifying harmful lead exposure in wild mammals through hair analysis https://www.biorxiv.org/content/10.1101/2023.03.13.531209v1?med=mas

Exposure to the persistent organic pollutant 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, dioxin) disrupts development of the zebrafish inner ear https://www.biorxiv.org/content/10.1101/2023.03.14.532434v1?med=mas

N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters https://www.biorxiv.org/content/10.1101/2023.03.14.532631v1?med=mas

In search of a unifying theory of white matter aging: tract morphometry-microstructure relationships https://www.biorxiv.org/content/10.1101/2023.03.14.532658v1?med=mas

Asynchronous phylogeographic and demographic dynamics of rodent community in the low latitude Asia https://www.biorxiv.org/content/10.1101/2023.03.14.532549v1?med=mas

Transposon-encoded nucleases use guide RNAs to selfishly bias their inheritance https://www.biorxiv.org/content/10.1101/2023.03.14.532601v1?med=mas

Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration https://www.biorxiv.org/content/10.1101/2023.03.14.532519v1?med=mas

Engineering the biological conversion of formate into crotonate in Cupriavidus necator https://www.biorxiv.org/content/10.1101/2023.03.14.532570v1?med=mas

A synthetic biology approach defines mechanistic and regulatory roles for phase condensation in the assembly of microtubule architectures by human TPPP https://www.biorxiv.org/content/10.1101/2023.03.14.532644v1?med=mas