Gaspar Jekely @jekely@qoto.org
- Platynereis connectome
- https://catmaid.jekelylab.ex.ac.uk
Professor at Centre for Organismal Studies (COS), University of Heidelberg, Germany
and
Living Systems Institute (LSI), University of Exeter, UK.
#neuroscience of marine larvae, #connectomics, #cilia, ciliary swimming, cell and nervous system #evolution, #GPCR, #neuropeptides, #Platynereis, #Trichoplax, #Nematostella, #Schistosoma, #coral #neuroscience #rstat #evolution
Joined Nov 2022
Dear fellow Mastodoners, To help the #TwitterMigration I only post teazers on twitter with a link to the mastodon content and a short message:
"Join us on the other side. Open, distributed, community driven, no ads, no AI feeding you, no random retweets, full control."
you could do the same
Finally, here is the Editor's evaluation from @elife
This paper reports on the development of an impressive microfluidic platform for the study of motility, and motility transitions, exhibited by single algal cells in circular confinement. Building on previous work that showed a three-state motility repertoire for certain green algae, the present work uses extremely long time series and a variety of physical perturbations to show how those dynamics can be altered by environmental conditions. The work will be of interest to a wide range of scientists studying motility and non-equilibrium dynamics.
https://doi.org/10.7554/eLife.76519.sa0
The authors also developed and tested a novel droplet-fusion assay to expose single cells in a controlled manner to chemicals. This could be a very elegant way to e.g., dissect #signalling mechanisms in the cells by #pharmacology.
The motility is light-switchable, which was known, but the long-term imaging of single cells in light and dark revealed a cellular #memory: the light-altered behavioural state persisted after light off.
The locomotion of single-cells is characterised by a trio of motility macrostates (run, stop, tumble) with distinct transition probabilities that could be quantified by long-term imaging.
#Chlamydomonas (2 #cilia) and #Pyramimonas (8 cilia) #algae were encapsulated into droplets by #microfluidics and imaged at high speed to characterise gait switching dynamics and the effect of light.
Great paper: a droplet #microfluidics assay to encapsulate single micron-sized algae to study long-term #behaviour.
https://elifesciences.org/articles/76519#fig4
by Bentley et al. gielenlab.com and @micromotility
A thread.
Gaspar Jekely
boosted
Hello, #GEOMAR is #newhere on Mastodon.
We are the Helmholtz Centre for #OceanResearch based in #Kiel, Germany.
We study the global #ocean from the #seafloor to the #atmosphere, covering a spectrum of physical, chemical, biological and geological processes in the ocean.
Follow us for the latest news from #oceanscience and #climateresearch and feel free to check out our website:
www.geomar.de/en
Member of the #Helmholtz community @helmholtz
Gaspar Jekely
boosted
Hi #ScienceMastodon, time for an #introduction!
I'm an #EvoDevo biologist interested in how tissue #mechanics influences the #evolution of #morphogenesis. I study a deep and mysterious epithelial invagination that forms at the head-trunk boundary of #flies during #gastrulation, known as the #CephalicFurrow (see video below!). Currently, based in Germany as a postdoc in the Tomancak Lab at MPI-CBG. Looking forward to meeting you!
Gaspar Jekely
boosted
RT @GRC_CMM
Hey #cilia & #centriole tweeps- we are just under two weeks from our deadline ⏳December 5th⏳ for abstracts for talk slots at 2023 GRC Cilia, Mucus and Mucociliary meeting in Barga, Italy! #RareDisease #Therapeutics #Biophysics #Biofilms #Mucus #CF #PCD https://www.grc.org/cilia-mucus-and-mucociliary-interactions-conference/2023/
Gaspar Jekely
boosted
4 yr PhD in Manchester, UK: The evolution of nerves: understanding the roots of neurodegeneration
TRAINING in evol. biol., biochem., expansion or electron microsc., cell culture, #Drosophila genetics, #scicomm
SUPERVISION: Prokop/Allan/Ronshaugen
The paper is by Justine M Pinskey et al. Daniela Nicastro's lab - are you on Mastodon?
and the ciliary vane, which is very different from the mastigonemes of e..g. #Chlamydomonas
A cilium with wings.
Beautiful #cryoET paper on choanoflagellate #flagella #cilia revealing the enigmatic ciliary vane, new components and similarities to animal cilia
#protist #evolution #EM #choanoflagellate
https://elifesciences.org/articles/78133
Gaspar Jekely
boosted
Time for my #neuroscience #introduction here. I am studying the nervous systems of jellyfish using computational modelling, trying to understand their dynamics and their evolution. I use biophysical neuron models and feed the resulting dynamics of their network into fluid dynamics simulations to study how their neuronal dynamics control the swimming and turning of these strange creatures.
Gaspar Jekely
boosted
@Mill_lab @florianjug While I left the other site behind, I still keep a foot there to drag out stragglers.
On the energy, it's deliberate. This is a time of great opportunity to shape the public discourse channels of the scientific community for years to come. So I got to work to assist as best I know.
I've been in online communities since 1995, when my parents bought an intel 386 "clone" (as we called them back then) with (the horror) MS Windows 95 and dial-up internet. Living in online communities comes natural. Been a moderator of IRC chats, poetry forums, software forums, and more, for decades.
One aspect I see as key is a variation of the founder effect: nobody moves unless there's something to move into, and there won't be something to move into unless most move. To push over this bistable system into its other state, energy must be applied. Here, "something" is both interesting commentary, links, news, photos, and more, as well as people with similar interests.
Putting in energy (time and effort, really) at the beginning can make a dramatic difference to the outcome. My approach was then, indeed, deliberate: post here what I used to post on the other site, reach out to those who have moved and engage with them, lure those on the other side with links to here and never the other way, promote here relevant news (job posts, conferences, papers) and showcase examples of community-triggered switching (publishers and journals), stimulate commentary, seed insight.
Eventually I'll wind down, but at the moment, this fire needs kindling. So far, so good.
Gaspar Jekely
boosted
We have an exceptional opportunity at our center for a new group leader at VIB in Leuven. We are looking for a new colleague who wants to use computational methods to investigate molecular and/or cellular aspects of neurobiology. This position not only comes with substantial and renewable core funding and start-up package, but it is also linked to a tenure track position at KU Leuven.
More information on our center can be found on our website https://cbd.sites.vib.be/en.
Gaspar Jekely
boosted
Neuro-evo conference at HHMI Janelia on May 15-18, 2023. Join us for the third edition!
Application deadline: Jan 27 (11:59 p.m. EST) 2023.
"Historically, with the study of the most convenient animal models —from the giant axon of the squid and the lobster's stomatogastric circuits to Aplysia's synapses and C. elegans' circuits — neuroscientists revealed some of the operating principles of the nervous system, which were then found to apply broadly across phyla. The third instalment of this meeting will once again bring together neuroscientists working on a broad diversity of animal models in an effort to compare circuits across phyla as a means to crack their function."
#NeuroEvo #Janelia #HHMI #conference #science #academia #neuroscience #DevBio #connectomics #connectome
- Platynereis connectome
- https://catmaid.jekelylab.ex.ac.uk
Professor at Centre for Organismal Studies (COS), University of Heidelberg, Germany
and
Living Systems Institute (LSI), University of Exeter, UK.
#neuroscience of marine larvae, #connectomics, #cilia, ciliary swimming, cell and nervous system #evolution, #GPCR, #neuropeptides, #Platynereis, #Trichoplax, #Nematostella, #Schistosoma, #coral #neuroscience #rstat #evolution
Joined Nov 2022
