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《2.7% 的武汉居民产生有效抗体》 中国科学报报道,工程院院士王辰等研究人员在《柳叶刀》期刊发表研究报告,这是至今观察时间最长的血清流行病学追踪调查。此次研究是在 2020 年 4 月武汉解封后,选取武汉所辖全部 13 个区,以严格的多阶段整群随机抽样方法,对 3556 个家庭计 9542 名居民的代表性样本进行进行现场问卷及咽拭子核酸、血清新冠病毒抗体检测,随后在 6 月以及 10-12 月进行随访。调查结果显示,在 9542 名受试者中,532 人新冠病毒抗体呈阳性,经校正后,人群抗体阳性率为 6.9%,这说明即便经疫情暴发,仍仅有小比例人群受染。在这些抗体阳性者中,有 82% 属于无症状感染者,且只有 40% 产生了中和抗体(可有效对抗病毒的功能抗体),而这部分人群仅占武汉人群的 2.7%,这足以说明人群仍普遍缺乏对新冠病毒的免疫力,需防止大流行再发生。 | solidot.org/story?sid=67256

1. set a goal for the year
2. spend all of january studying the theory behind it
3. become very aware of how to do the thing
4. wait do i need to work to achieve this goal? like. continuously? often?
5. fuck

I worked over 5 days on this one and I am so glad I turned out like this. I feel like I improved so much with ink and watercolor recently.

This is St. Nicholas Church in Malá Strana, Prague

30x40 cm ink, watercolour and gouache on paper

It always felt wrong to start a programming language design already having a type system in mind. I couldn't put my finger on it before, but now I think I understand why.

There is well known tradeoff between exploration and exploitation when it comes to solution search.

During *exploration* you try to open undiscovered areas. Something that might not be very viable at the beginning but in the long run could lead to outstanding results. During *exploitation* you try to find best solutions in selected area, relying on already accumulated assets.

Eventually exploration and exploitation would be in conflict, since resources are limited. You can resolve this conflict differently depending on the task you're trying to accomplish.

If you want to design a PL that is more convenient for humans, starting with a type system in mind would pull you away from exploration too early. There might be a brilliant solution that is incompatible with that type system.

You can always think how to limit flexibility and reduce space for errors later.

一时冲动,我就买下了
法语词汇渐进
明明语法的还没做完

2021-03-16, 10:20, Tuesday

So I had an anxiety attack last night. Managed to get some sleep, but clearly not enough. Trying to relax and do some errands like pruning my houseplants and organizing drawers. Come to think of it, I might get a bonsai...

Anyhow, the name of the game is taking advantage of the situation. I now have a uniqye opportunity to watch all of my classes recorded from zoom, and that's why I can relax now for a bit and catch up later. Gotta write some of that novel now.

I love language. Image source i.redd.it/7syim1p0e6n61.jpg, no idea what thread, I don't use Reddit.

Gather 还挺有趣的,啥时候跟别人约着玩玩好了2333

Can someone think of an example of a scientific theory that got superseded by a better one and then got re-incorporated into scientific consensus again?

In my field, I can name only one such theory: Lamarckism - the notion that an organism can pass on to its offspring characteristics that the parent organism acquired through use or disuse during its lifetime.

It became superseded by Darwinian notion of evolution but since discovery of epigenetics, it became more and more obvious that things are not nearly as simple and cracking the genetic code of the individual would tell only a fraction of information about it's genetic expression.

All the genes' expression are influenced by epigenetics which is in part influenced by the lifestyle of the progenitors.

2021-03-12, 08:43

Right, forgot an important thing. I'm on my third day without caffeine (not counting tea, but I need to drink something hot). I feel slightly less alert in the mornings, sleep better, way less jittery and anxious. I do miss the taste though. Not quite sure if the tradeoff is worth it, but it's good to have some stability for once.

An important feature is pain tolerance. When I have caffeine in my system it gets harder to tolerate pain, especially sharp one. And I get injections for avitaminosis every second Sunday, so it makes sense to keep this "fast" going for at least another few days.

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