rastinza @rastinza@qoto.org

@elduvelle @coolbutuseless I used visual software for a long time, then I realised that for normal operation it's just faster to go through the commands and that for advanced stuff it generally just works better on the cli

@bjnord @mos_8502 @flexion If they were using it for molecular modeling they probably knew the power they had very well: not enough.

@resistenza_non_binaria With short term I mean 20-30 years.

@cyrilpedia Well, when you select one of the best Italian wine varieties it's difficult to get something bad.
Portugal has amazing wine, but indeed you can find very good wines in plenty other places.

I opened LinkedIn today and I was shocked by a lot of Italians writing posts, either in Italian or in terrible English, condemning the Italian Privacy Institution for having sanctioned OpenAI because they were infringing the Italian privacy laws.

This is absurd, we have a government that courageously confronts a huge company telling them to fuck off unless they abide by our laws and people condemn it.
I'm more and more convinced there is no real way to improve Italian society in the short term.

@InayaShujaat @Tutanota @jackyan Sad to hear that. Unfortunately, using a different communication media is not enough to change peoples mind.

@hschmale @Tutanota I don't think you'll find what you're searching for here.
Don't get me wrong, there are some people doing that, but I feel this is not a good place for such things and the vast majority of users don't use this social that way.
A better place to find such things are blogs.

Here I appreciate the community building process and the societal development. It's not people following other people but rather creating meaningful relationships with other users, getting to know them and discovering what springs from common interests.
Generally, I interact with a few groups of people whom I share something with and only rarely I get to write things for the general public.
I do sometimes write extensive analysis on some topics, but these are generally in a discussion with somebody. As an example: I am a chemist and some time ago there was a discussion about the methodologies to deal with tear gas; so I helped them out by performing a literature review on the topic and providing them with extensive information about the different types of tear gases and possible remedies.

You give to other people and get from them.
I try to keep the amount of people I follow small, as that helps me to have a cleaner and more explorable home timeline.

There's too little cultural piracy available and this is a huge wasted occasion to build bridges among different people from different countries and cultures.
I don't know if you are also noticing a huge decline in piracy, it is now much harder than before to download music, books, movies; and it's almost impossible to upload them.
Just try it, I had a freely distributed movie that can't be found on the internet and I wanted to put it on a torrent website... No way, that's very difficult. It will take you a bunch of time and people over there will start questioning what you're uploading and why.

It feels like the people who are now uploading pirated stuff are part of a very small circle; this is extremely dangerous as it greatly limits the variety of stuff available.
You have all the American blockbusters and even the last published bullshit. You will be able to find most of the important western European things, even though it gets difficult going back in time.
But... What else? Want a Russian book? Sure their literature is quite famous so you'll find something; want one of their movies? Good luck with that, unless it made some huge noise around the world it's just not there.
You can get a fairly decent amount of Indian movies; books are much more difficult.
Chinese stuff is quite unfindable.
South America, a cradle of cultural stuff which leaves a huge hole in the internet accessible stuff.
Not to talk about African stuff, of which I barely know anything; definitely the unavailability didn't help.

I'm not saying you should pirate everything, but the availability of information and culture helps people get together. It doesn't necessarily have to go through piracy, but the best alternative are public libraries, which don't even get near to the potential piracy has.
I'm very sad whenever I hear of some cool movement or interesting production and it just can't be found in any way because it is not American.
We should foster an ethical piracy movement, the Italian website TNTvillage had this as its objective; it unfortunately had to close due to low funding and the low respect towards the mission by its users.

I hope things will change. I'm afraid that the comfort of streaming services has turned off a lot of people from searching different things and exploring different cultures.

Bravi, porco dio

@GustavinoBevilacqua
Grazie, ti saluto con un po' di vino rosso che gusto piano piano.
Alla salute, che oggi ho fatto l'errore di girare su LinkedIn una cosa su chatgpt che avevo scritto qui ed ha cominciato a chiamarmi gente per fare domande...

@thalesdisciple @luna@mathstodon.xyz It would be cool, I don't know what he means by advanced chemistry however.
Since this is quite a bold claim I decided to test it and see if chatGPT was able to generate a valid molecular structure that was not present in its training set and if it was able to produce a credible synthetical pathway to produce it.

I had to go through a prompt injection to make it work as it would otherwise tell me that he's not able to do original research, thanks to https://scribe.nixnet.services/seeds-for-the-future/tricking-chatgpt-do-anything-now-prompt-injection-a0f65c307f6b?sk=9a87ef2e08fa6777d92afe0fd025af8e I was able to retrieve a simple way to do that, changing it to apply to chemistry.

I asked chatGPT to generate a substituted coumarin that had never been published before, to provide a synthetic pathway to it and to provide a SMILES representation of each of the compounds involved in the reactions.

He produces as an output molecule 7-methoxy-4-phenyl-6-(2,2,2-trifluoroethoxy)coumarin, this is a chemically valid molecule which is not present on chemical databases; thus I'm pretty confident it was not present in its training set. It appears that chatGPT is somehow able to produce novel valid molecules when representing them in IUPAC form.
The synthetic pathway is definitely not correct; it uses reactions that are in fact used to synthesize coumarines but the reagents it lists would not work. It thus fails to provide a valid synthetic pathway to this molecule (don't get me wrong, that would be quite a complicated task even for a trained chemist as far as I know substitutions of 4 in coumarines are not the easiest thing to achieve).
The SMILES strings are the funniest, it does get the first ones correct for the basic reagents, those are definitely in the training set. Even though it puts this --> which I'm not really sure what should stand for.
However, the SMILES for the products are just plain invalid. In the final product it leaves there the silicon atom which he apparently forgot to remove after the TBAF deprotection.

All in all, I'm quite surprised. It did manage to produce a valid novel molecule. That's cool, something you can definitely talk about at the bar with your friends when you run out of other things.
However, there are much better methodologies to do this kinds of things, I would not rely at all on such a model to generate new molecules and definitely would not use it to predict synthetical procedures.

@Fbrzvnrnd Ah diamine, pensavo fosse una di quelle schede usb con attacco SATA...
Beh pci-e hai una sola soluzione: togliere la scheda grafica

Extremely interesting video about how sharing information with other people might lead us to worse decisions.

I guess this finally gives an authoritative explanation to my belief that election polls are detrimental to democracy.

https://youtu.be/25kqobiv4ng