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ExplaiNN provided great insight into the wide range of IRF4 binding motifs, returning Importance scores that clearly highlight the novel motifs targeted by IRF4 9/12

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The binding data showed in particular that the mutation was allowing the TF to stick to novel target sequences, most strikingly those having a GATA instead of a GATA in the motif 7/12

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to show that the mutations were indeed causing IRF4 to stick to a much broader range of DNA sequences 6/12

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RT @gobeirne
16 years ago, two future New Zealand Prime Ministers hanging out in Hyde Park, London.

RT @kstsosie
“As a scientist, I’m a fan of open data. But we are not yet ready for open data.” @YrachetaJM at giving a much-needed overview of how far legal protections need to advance in order to be equitable for Tribal Nations

Interesting sign on top of Meridian Mall. Looks like there's an important story behind it. Perhaps a previous building?

One of the better Otago pinots I have tried. And they tend to be quite nice as a baseline.

RT @boris_ctcf
🎖An atlas of transcribed human cardiac promoters and enhancers reveals an important role of regulatory elements in heart failure.

Deviatiiarov, R.M., Gams, A., Kulakovskiy, I.V. et al.
Nat Cardiovasc Res (2023). doi.org/10.1038/s44161-022-001

RT @saezlab
Building a knowledge graph for biomedical tasks usually takes months or years. 😰 What if you could do it in weeks or days? 🏃 We created BioCypher (biocypher.org) to make it easier than ever, but still flexible and transparent. 🧵⬇️

RT @erlichya
A wall sized poster of metabolic pathways in the restroom of a top biotech VC.

The bottom right red sign says "You are here" next to Urea

The upper left red sign says "Or maybe here" next to methane

Well played 😊💫💯

RT @CMA_Docs
The introduction of seamless, accessible electronic medical records is overdue.

To ensure the delivery of appropriate, effective care across the system, @clairehsnyman underscored that patients and providers require timely access to the information they need.

RT @flyerswitch
Hi - I’m Mio! I’m the artist behind both the 2023 @GoldenKnights pride jersey and the 2022 @Canucks pride jersey :) <333

RT @Scholar_Melinda
🌻🚨Excited to share I’ve joined the Geography & Atmospheric Science & Indigenous Studies Department @KUIndigenous at @UnivOfKansas where I’ll have my own lab to continue Indigenous environmental science research as a tenured track Prof!

RT @jburnmurdoch
NEW: conservatives have a Millennials problem.

In both UK & US, it’s not just that Millennials aren’t voting conservative because they’re young.

Every previous generation grew more conservative with age, but Millennials are not playing ball.

My column: enterprise-sharing.ft.com/rede

RT @NickIwanyshyn
Video showing a row of houses along Lake Erie completely covered in ice following the winter storm that swept through much of Ontario last week

RT @VisualCap
In our signature style⁠—combining art, data, and storytelling⁠—we've helped millions of people make sense of unfolding events, from geopolitical flare-ups to stock market turmoil 🌟

See our Top 22 Visualizations of 2022:
visualcapitalist.com/our-top-2

1. World's Population at 8B

The fjords of Aotearoa are as breathtaking as their Norwegian brethren.

The Argentines were out in force tonight in Queenstown. Messi may have heard them.

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