Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there??
https://www.biorxiv.org/content/10.64898/2025.12.12.693869v1
RE: https://mastodon.online/@neuroinformatics/115643481413121555
I'll be coordinating the "Animals in Motion" track of this summer school, returning to London in August 2026.
Apply to join us for some hands-on learning and collaboration on open-source tools for video behavioural analysis.
1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs.
🔗 https://doi.org/10.1101/2025.11.25.690220
Spatially-local inhibition and synaptic plasticity together enable dynamic, context-dependent integration of parallel sensory pathways https://www.biorxiv.org/content/10.1101/2025.10.18.683230v1?med=mas
subtooting prestige neuroscience
We discussed the same paper in a journal club in the lab. We had similar thoughts: circular analyses and "carefully" constructed statistical comparisons. It was shocking to see that the source data provided was just averages.
Another thing to notice is that the peer review reports are missing, must have been a tough battle. The number of reviewers was probably higher than three.
see the thing about making the underlying data of a paper available is that it has nothing at all to do with helping people understand what you're saying about the data. it's more about being able to believe anything you are saying about the data.
It's not even adversarial, it's just a basic fact of how science should be done: you have made a factual claim on reality, show your work.
Neuroscientist postdoc. Interested in ethologically-relevant neural coding, vision and decision-making. Currently based at the Department of Basic Neurosciences (UNIGE).