Stefan Köstler @stefankoestler@qoto.org
Researcher of chromatin structure and transcription by microscopy and molecular biology.
Joined Nov 2022
Stefan Köstler
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RT @BenLehner@twitter.com
Excited to start recruiting postdocs + research assistants to my lab @sangerinstitute@twitter.com
Massive mutagenesis to make biophysics + human genetics predictive? allostery, affinity, stability, splicing, receptors, TFs, cancer. pls RT
http://tinyurl.com/bmb9vv5s
http://tinyurl.com/49f3ubc3
Stefan Köstler
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My dear Chromatin Friends please help me spread the word and also register if this thrills you!
Boosts very much appreciated!
Please join us for the upcoming #ChromatinCon!
3 days - January 23rd ‐ 25th, 2023 - filled with lots of science around Epigenetics in Aging & Disease!
Stefan Köstler
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RT @davidlandeira@twitter.com
Our paper showing that changes of Polycomb activity during interphase transition modulate the ability of pluripotent cells to enter differentiation is out. Thanks to the team and collaborators!
https://www.nature.com/articles/s41467-023-35859-9
Stefan Köstler
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Loss of epigenetic information as a cause of mammalian aging https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7
▶️ Cellular responses to double-stranded DNA breaks erode the epigenetic landscape
▶️ This loss of epigenetic information accelerates the hallmarks of aging
▶️ These changes are reversible by epigenetic reprogramming
▶️ By manipulating the epigenome, aging can be driven forward and backward
Stefan Köstler
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RT @tpc_tom@twitter.com
Want to find out about how Wellcome’s Discovery Research funding can support you and your ideas? Join us between March and May at one of eight events across the UK and RoI, or at a virtual event if you can’t access these. https://Wellcome.org/what-we-do/discovery-research/regional-events @wellcometrust@twitter.com @PhysicsofLifeUK@twitter.com
Stefan Köstler
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RT @rkoszul@twitter.com
What happens when bacterial genomes are put in a eukaryotic context? A lot! Both expected and surprising!
We characterized chromatin assembly, activity, folding and compartmentalization of Mb long bacterial genomes put in a yeast nucleus. A v2! #3Dgenome
https://www.biorxiv.org/content/10.1101/2022.12.21.520625v1
Stefan Köstler
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🚨 Wed 18/11 - 16:00 UK - 5th @TLM_Cambridge 2022/2023 Online Seminar🚨
"Extracting the Invisible from Live Cell Microscopy"
Dr. @AssafZaritsky @bengurionu
To attend online please register to our:
https://lists.cam.ac.uk/mailman/listinfo/ucam-tlm-talks
📧
Stefan Köstler
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1/ Our cafeteria feeds @viennabiocenter scientists all week, including weekends. 3 meals, salad bar, desserts – plenty of choice. Most diners pay little attention to the logo on the ketchup. Fewer still know that the brand’s history is tied to the campus origins. A #history🧵.
Stefan Köstler
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Due to internal promotions, we have two fantastic opportunities to join our team here in Cambridge, UK:
- @the_node Community Manager (part of the @Dev_journal team):
https://www.biologists.com/wp-content/uploads/NodeComMan.pdf
- Science Communications Officer
(part of the Marketing team):
https://www.biologists.com/wp-content/uploads/Science-Communications-Officer.pdf
Applications for both positions are open until 15 January 2023.
#Vacancies #Publishing #Co_Biologists #AcademicMastodon #Science #Biology
Stefan Köstler
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And, for @NIH@twitter.com colleagues, I am talking at NIH on Tuesday afternoon on Genomics, Imaging, and AI, three technologies which are changing basic research and clinical practice https://www.genome.gov/event-calendar/genomics-imaging-and-AI-three-technologies-that-are-changing-biological-research-through-to-clinical-practice
Stefan Köstler
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RT @mitchguttman@twitter.com
What are the functional roles of 3D genome organization? In a new preprint led by @_prashantbhat@twitter.com, we demonstrate a critical role for dynamic 3D organization of genomic DNA around nuclear speckles in controlling the efficiency of mRNA splicing.
https://www.biorxiv.org/content/10.1101/2023.01.04.522632v1.full.pdf+html
🐦🔗: https://twitter.com/mitchguttman/status/1611416483883782145
Stefan Köstler
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RT @teraxurato@twitter.com
New preprint alert!!
We made the first transgenic ants, expressing GCaMP in the antennae (pic), to study how the ant brain encodes social signals. We discovered a core glomerulus in the brain that responds to alarm pheromones.
https://www.biorxiv.org/content/10.1101/2022.12.04.518909v1
[1/XX]
🐦🔗: https://twitter.com/teraxurato/status/1608928543261741057
Stefan Köstler
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RT @vitaliikl@twitter.com
What regulates alternative splicing? RBP binding to RNA? TF binding to DNA? TF binding to RNA?
Are there systematic studies and sequence-based models of this process?
Any references would be appreciated.
🐦🔗: https://twitter.com/vitaliikl/status/1608360633266847744
Stefan Köstler
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Our latest work on computer simulation of #chromatin appeared in its final form today. Fully extruded loops mediated by #cohesin and #CTCF have increased contact probabilities within loops. Microloops manifest without additional factors. Effects depend on nucleosome positions. It is freely available online until end of the year with https://authors.elsevier.com/a/1g4Hg1SPT0FkK
Stefan Köstler
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RT @carninci@twitter.com
While Christmas is approaching, I’d like to announce that I’m hiring! Looking for a technician/senior to develop and implement genomic technologies (of the type like CAGE, Radicl-seq etc) to broadly map functions of lncRNA and the noncoding genome. https://careers.humantechnopole.it/o/techniciansr-technician-carninci-group-genomics-research-centre
Stefan Köstler
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Postdoc position! Pls boost!
Want to devote your expertise in data science to accelerate the pace at which new medicines are found?
Join our lab at the Broad Institute in Cambridge, MA, USA to glean insights from biological images!
More info: http://broad.io/mlcbpostdoc
The Broad Institute provides a uniquely stimulating environment to advance and apply data science in collaboration with MIT, Harvard, and hospitals. (1/2)
Stefan Köstler
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Now that it's clear that speakers can share their own talk and that @ASCBiology@twitter.com will not change its pricing policy, here's my talk: https://youtu.be/REvHa8KAw1A
RT @christlet@twitter.com
To anyone considering getting charged 150$ to see my
@ASCBiology@twitter.com subgroup talk at #CellBio2022 using the on-demand service: contact me and I'll be happy to send you a link, free of charge. I encourage other speakers to do the same✌️ https://twitter.com/micahschott/status/1601974477868470275
🐦🔗: https://twitter.com/christlet/status/1601977212164608002
Stefan Köstler
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RT @castello_lab@twitter.com
Two days left for our PhD position on RNA-binding proteins and viruses. If you are interested, submit your application here (https://www.gla.ac.uk/explore/jobs/) before the 12th of December 2022.
REFERENCE: 102328
🐦🔗: https://twitter.com/castello_lab/status/1601522227253760000
Stefan Köstler
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Our lab account @teiflab is now also at Mastodon!
Stefan Köstler
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Yesterday, I gave a lecture about #SMLM as part of Bryan Millis's #Microscopy Education Program "Widening the Lens"🔬 sponsored by #cziscience #imagingthefuture - You can find my presentation on #figshare - Feel free to reach out in case of questions - Enjoy 😀👉 https://figshare.com/articles/presentation/Single-Molecule_Localization_Microscopy_Theoretical_Basis_and_Practical_Guide/19902511
#superresolution #nanoscopy #womeninscience #imageanalysis #imaging
Researcher of chromatin structure and transcription by microscopy and molecular biology.
Joined Nov 2022
