#antiviral

A special type of chewing gum can “trap” and neutralize some influenza and herpes viruses, according to new experiments from scientists in the U.S. and Finland. @ScienceAlert reports:
https://www.sciencealert.com/new-virus-trapping-gum-could-help-neutralize-herpes-infections

#Health #AntiViral #Gum #Virus #Influenza

Researchers have developed a clinical-grade chewing gum with antiviral properties that can reduce viral loads of herpes simplex and influenza A strains by over 95%! The study, published in Molecular Therapy, shows promising results for controlling virus transmission. #antiviral #research #health : https://www.eurekalert.org/news-releases/1079516 #newz

Ebola-infected monkeys cured with a pill, sparking human treatment hopes

https://medicalxpress.com/news/2025-03-ebola-infected-monkeys-pill-human.html

#ebola #infection #primates #medicine #healthcare #virus #antiviral #drugs #biology #research #pharmaceuticals #goodnews

Will we soon have a broad-spectrum #antiviral?

Synthetic heparan sulfate mimics based on chitosan derivatives show broad-spectrum antiviral activity | Communications Biology

https://www.nature.com/articles/s42003-025-07763-z

#Antiviral use and the effects of #drug #resistance on the #transmission dynamics of #influenza, https://etidiohnew.blogspot.com/2025/03/antiviral-use-and-effects-of-drug.html

#BREX system's unique #DNA_recognition mechanism enhances #bacterial #antiviral defense.

#bacteriophages #methyltransferase

https://phys.org/news/2025-03-brex-unique-dna-recognition-mechanism.html

The Zorya Anti-Phage Defense System sounds like a hardcore sci-fi missile defense deployed by the Xanthan Conglomerate over their Ytterbium mines. It isn’t, but it kinda sounds like it is.

https://phys.org/news/2025-01-bacteria-anti-missile-defense-fend.html

#bacteria #phage #scifi #medicine #biology #antiviral

But yes, it's #BusinessAsUsual because #Crapitalism requires people to #ConsumeConsumeConsume!

Canadian teen with #BirdFlu was on #LifeSupport, new report reveals

The hospitalized teen was also given three #antiviral treatments, underscoring how severe #H5N1 infection can be

By Nicole Karlis, January 6, 2025

"In November, a teenager in British Columbia was infected and hospitalized with bird flu, caused by the H5N1 virus. While most cases have been mild, commonly characterized by #conjunctivitis and respiratory symptoms, this previously healthy Canadian teen was hospitalized from the virus in critical condition. Their symptoms started with double conjunctivitis, also known as pink eye, and turned into a fever and coughing. A few days later the teenager was admitted to intensive care after developing acute respiratory distress syndrome [#ARDS].

"'This was a healthy teenager prior to this, so no underlying conditions,' said British Columbia’s health officer, Bonnie Henry, at a news conference at the time. 'It just reminds us that in young people this is a virus that can progress and cause quite severe illness.'

"Now, a recent report brings to light more details about the teenager’s case. In the report, published in the New England Journal of Medicine (NEJM), researchers explain that the 13-year-old girl spent weeks fighting for her life after contracting a severe H5N1 infection from an unknown source. In finding her diagnosis, researchers say that she initially tested positive for influenza A, but not the seasonal subtype. Further testing suggested she had a high viral load of a novel influenza A infection, which researchers discovered to be the H5N1 avian flu.

"The next day doctors started her on oseltamivir, also known under the brand name Tamiflu. However, her respiratory functions declined rapidly causing her to be intubated. She was also placed on extracorporeal membrane oxygenation (ECMO), a machine that is a form of life support for people with life-threatening illnesses. In addition to the ECMO machine, the teenager received a plasma exchange and two more antiviral medication treatments — amantadine and baloxavir.

"In an accompanying editorial, experts noted while mutations were detected in her case, it’s 'unclear whether these #mutations were present in the infecting virus or emerged during the course of the patient’s illness.'

"In other words, it’s unclear if the virus #mutated to be more severe in humans.

"'The mutations evident in the Canadian case highlight the urgent need for vigilant surveillance of emerging mutations and assessment of the threat of human-to-human transmission,' the editorial stated, adding that vaccine development and therapeutics are also needed — perhaps to treat more severe illness. 'The Canadian case showed higher viral loads in the lower airway and very prolonged shedding, despite therapy, which highlights the potential need for longer therapy.'

"Researchers concluded their editorial with an acknowledgment that 'many questions remain.' For example, the severity of cases is likely to depend on host immunity, the route of exposure, or other changes in the virus.

"Currently, the CDC says that the risk to most Americans remains low.

"'We do have candidate vaccines and antivirals available to try to mitigate severe influenza in the case of wider spread,' the report stated. 'That said, a balance between enhanced vigilance and ‘business as usual’ is needed."

https://www.salon.com/2025/01/06/new-report-on-severe-case-of-canadian-teen-with-bird-flu/
#HPAI #BirdFluMutations #Flu

HELIOX: WHERE EVIDENCE MEETS EMPATHY • DEC 30, 2024

Novel Antiviral Targets
Viral Methyltransferases

A new class of antiviral drugs that target viral methyltransferases. Moving beyond familiar treatments like Paxlovid, they discuss how these novel antivirals could potentially combat a wide range of viruses, from COVID-19 to Ebola and dengue.

COVID-19 & Public Health Podcasts
https://www.buzzsprout.com/240578

#ViralMethyltransferases #AntiViral #HelioxPodcast

https://www.buzzsprout.com/2405788/episodes/16349568

Potential life-saving healthcare news:

Scientists have pioneered antivirals targeting Covid, Ebola… offering a new strategy for treating RNA & DNA viruses.

#Healthcare #Antiviral #Medicine #Covid https://scitechdaily.com/beyond-paxlovid-scientists-unveil-game-changing-antiviral-that-could-combat-covid-ebola-and-more/

#Cellular #RNA plays key role in #antiviral defense, study finds

https://ground.news/article/cellular-rna-plays-key-role-in-antiviral-defense-study-finds?utm_source=mobile-app&utm_medium=newsroom-share

#US #NIH #Study Finds #Tecovirimat Was Safe but Did Not Improve #Mpox Resolution or #Pain, https://www.nih.gov/news-events/news-releases/nih-study-finds-tecovirimat-was-safe-did-not-improve-mpox-resolution-or-pain

#Antiviral drug tecovirimat did not reduce time to lesion #resolution or have an effect on pain among adults with mild to moderate clade II mpox & a low risk of developing severe disease, according to an interim data analysis from international clinical trial called the Study of Tecovirimat for Mpox (STOMP). There were no safety concerns associated with tecovirimat.

Gingko
Kurkuma
Beifuss artemesia annua
Nigella sativa Schwarzer Kreuzkuemmel
Ingwer
Knoblauch Allium sativum
Ceylon-Zimt
Rosmarin
Loewenzahn
Oregano Origanum vulgare
Holunder Sambucus nigra
Johanniskraut
Echinacea

#antiviral #phytotherapie #heilpflanzen #covid #h5n #mpox #viren #grippe #pandemie

https://www.the-sentinel-intelligence.com/p/does-this-stuff-even-work-yeah-looks

“In preclinical studies, spray offered nearly 100% protection from respiratory infections by COVID-19, influenza, viruses, and pneumonia-causing bacteria.”

#Covid
#COVID19
#NasalSpray
#AntiViral

https://news.harvard.edu/gazette/story/2024/09/drug-free-nasal-spray-blocks-neutralizes-viruses-bacteria/

Bacteria are just unbelievable ...
https://www.science.org/content/article/bacteria-use-crazy-molecular-mechanism-fight-viruses

#science #virus #bacteria #antiviral

#US #CDC Study Shows Early #Flu #Antiviral #Treatment Decreases #Risk of #Death, https://www.cdc.gov/flu/spotlights/2023-2024/2023-2024-study-treatment-death.htm

A new study suggests that starting antiviral treatment early reduces risk of death in adults hospitalized with flu. Study, published in journal Clinical Infectious Diseases, looked at data for more than 26,000 patients collected over 7 flu seasons (2012-2019) by Influenza Hospitalization Surveillance Network (FluSurv-NET), a population-based surveillance network sponsored by CDC.

Mpox Disease: The Antiviral Tecovirimat (TPOXX) Found Ineffective in Clinical Trial
The monkeypox virus (MPXV), called so because of its first discovery in monkeys kept in research facility in Denmark, is closely related to variola...........
#antiviral #AntiviralDrug #DRCongo #monkeypox #monkeypoxvirus #Mpox #MPXV #Tecovirimat
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/mpox-disease-the-antiviral-tecovirimat-tpoxx-found-ineffective-trial-in-dr-congo/

An ex vivo #human precision-cut #lung slice #platform provides insight into #SARS-CoV-2 #pathogenesis and #antiviral drug #efficacy, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00794-24?af=R

We identified early induction of specific #cytokines, especially IP-10 and IL-8, as potential predictors for severe #COVID19, & uncovered a hitherto unrecognized phenomenon that while infectious virus disappears at late times of infection, viral #RNA persists and lung histopathology commences.

#Molecular #surveillance of #influenza A virus in #SaudiArabia: #WGS and metagenomic approaches https://pubmed.ncbi.nlm.nih.gov/38904365/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10ykRO9og5pGdo51l9DEPEpOJ3DVFIn__QK2QPM3dci1C1dEYq&fc=None&ff=20240621125233&v=2.18.0.post9+e462414

One sample containing the #antiviral #resistance-mediating #mutation #S247N toward #oseltamivir and #zanamivir was found.

Solid Wood Surfaces Have Natural Antiviral Properties, Study Shows
https://www.sci.news/medicine/antiviral-wood-13031.html #wood #surfaces #antiviral