#CellPolarity
These are public posts tagged with #CellPolarity. You can interact with them if you have an account anywhere in the fediverse.
My Dresden colleagues have recently published a paper.
Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity
https://doi.org/10.15252/embr.202357181
https://twitter.com/ZerialLab/status/1686028788658847744?s=20
New paper from the Zerial Lab!
My colleagues and I have shown that apical projections across the bile canaliculi are load-bearing structures. These structures contribute to sustaining the anisotropic #growth of the nascent tube under increased intraluminal #pressure during #liver #development. These structures are supported by adherens #junctions and sealed by tight junctions.
I believe only @nunopmartins is here but if I am mistaken please tag any other author.
#CellPolarity #CellBiology #actomyosin #tubulogenesis
Bebelman and Bovyn et al. demonstrate that apical bulkheads,…
rupress.orgNot too bad #Galactica.
I tried with hepatocyte polarity
https://galactica.org/?prompt=wiki+article+on+hepatocyte+polarity
The AI nailed the principle of cell polarity and the description is pretty good.
I'm impressed that it got the "hepatic cord".
However, it completely missed the specifics of hepatocyte polarity: Hepatocytes have multiple basal and apical surfaces. Also, the fact that the apical surfaces are facing the gastrointestinal tract is not completely incorrect but a bit misleading.
#CellPolarity #AI #CellBiology