Geekmaster 👽:system76:

Had this article shared with me today: fortune.com/2025/02/11/ai-impa

I went through an array of #emotions. At first, I found it #awkward and #discomforting. I made jokes:

Wait, you mean people aren't thinking #critically and growing #cognitively because the #digitalization of the world is doing it for them....and it's making them (gasps) #dumber!!?? #AI is making it worse?? Is this #Idiocracy? 👀 😞 Am I being #punked right now!? Where's Ashton and the cameras! 📹

Then, I had a deep #selfrealization:

Jokes aside - This is a #sensitive topic for me. I talk about it in my closest circle too often. Unfortunately, I have a front seat to the steep cognitive #decline of some close #friends and #family members for years now, and it makes me sad - not because of disease or "old age", simply because of too much screen time and no new cognitive #stimulation. I see too many people purposefully avoiding nearly anything #cerebral, if they even approach them at all. I have many days where I wish the #Internet didn't exist - for a multitude of reasons, but this is a big one. I'm not trying to be "old fashioned" or #sarcastic, I'm just #disappointed in how we #humanz have grown to depend on #technology as a #crutch, rather than using it as the #tool it was invented to be. As the article eludes to, these technologies are supposed to #complement human #evolution, not #supplement it.

(part 1)

Feb 14, 2025, 18:07 · · · 1 · 0
Graham Perrin

I'm a shocking liar.

"In no particular order" was a blatant lie.

Eric came first because I have, more than once, used a GhostBSD-provided repository to complement my use of FreeBSD.

#LDWG #GhostBSD #FreeBSD #collaboration #crossover #complement #compliment #repo #repos #repositories #pkg #poudriere #packages

dada

Pack Tendinites - nutripure.fr/fr/complement-ali

Dites les sportifs, ça vous paraît bête comme achat ? Mon corps grince et si ça peut m'aider, ça peut être super.

#sport #complément #santé

Rhyothemis

@erictopol

Great post!

"Furthermore, there are complement inhibitor drugs (such as pegcetacoplan, iptacopan, and vemircopan) used for rare immune diseases that might be worth consideration for testing in Long Covid."

#LongCovid #complement

Paul Maidowski

Check out the fantastic upgrade our 'Living with #Covid' friends can now install, #SADS-CoV on top of #SARS-CoV-2. Sweet Lord do we need to add #'s to make any of this searchable? That's instagram-level of dysfunction ;)

Interesting discussion of the role of #complement in pathogenesis, incl. prominent role for #placenta-associated 8 protein (PLAC8) as an essential host factor #SARSCoV2 #SADSCoV pnas.org/doi/full/10.1073/pnas twitter.com/_ppmv/status/16777 @noyes

Rémi Eismann

One day, one decomposition
A030124: Complement (and also first differences) of Hofstadter's sequence A005228

3D graph, threejs - webGL ➡️ decompwlj.com/3Dgraph/A030124.
2D graph, first 500 terms ➡️ decompwlj.com/2Dgraph500terms/

#decompwlj #maths #mathematics #sequence #OEIS #javascript #php #3D #numbers #complement #FirstDifferences #graph #threejs #webGL

Hao Yin

Chromatin landscape dynamics of #SmoothMuscleCell in #Atherosclerosis🐭

Integrated scATACseq+scRNAseq+lineage tracing analysis reveals a protective role of ATF3 in atherogenic #Complement 3+ SMC

Dr. Ying Wang & Nicholas Leeper lab #CardiovascRes 2022
academic.oup.com/cardiovascres

J.H.Noyes

@jonaskunst

Re: #Temelimab (Anti HERV-env)

#PathogenicCoronaviruses are known for the severe amount of #Complement component activation provoked. In keeping with that, surface Complement Regulatory Protein #CD46 inducts HERV-Env via C3b attached to SCRs 2-4. Interestingly enough, the Split Complement products produced via CD46 mediated inactivation of #C3b and #C4b are #NRP1 ligands.

CD46 & HERV-Env: ncbi.nlm.nih.gov/pmc/articles/

NRP1: pubmed.ncbi.nlm.nih.gov/315724

Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement

The aberrant expression of human endogenous retrovirus…

www.ncbi.nlm.nih.gov
Katharina Schmack

No evidence for link between #complement C4 and #schizophrenia!

An impressive #medRXiv study in ~70k blood samples fails to detect association between #C4 genes and protein at birth and schziophrenia later in life. This is interesting because the strongest genome-wide association for #schizophrenia, found in the #MHC region, has so far been attributed to C4. May the search for other loci continue, I cannot wait to see the #GWAS mystery of schizophrenia unfold!

medrxiv.org/content/10.1101/20

The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

The complement system, including complement components…

www.medrxiv.org
WordofTheHour

#complement : the quantity or number required to fill a thing or make it complete

- French: complète

- German: die Ergänzung

- Italian: complemento

- Portuguese: complemento

- Spanish: complementa

------------

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WordofTheHour

#complement : the quantity or number required to fill a thing or make it complete

- French: complète

- German: die Ergänzung

- Italian: complemento

- Portuguese: complemento

- Spanish: complementa

------------

Report an incorrect translation @ wordofthehour.org/r/translatio

We need your help!! Help us improve our translations. :)

We rely on community members to help us improve our…

wordofthehour.org
WordofTheHour

#complement : the quantity or number required to fill a thing or make it complete

- French: complète

- German: die Ergänzung

- Italian: complemento

- Portuguese: complemento

- Spanish: complementa

------------

Report an incorrect translation @ wordofthehour.org/r/translatio

We need your help!! Help us improve our translations. :)

We rely on community members to help us improve our…

wordofthehour.org
WordofTheHour

#complement : the quantity or number required to fill a thing or make it complete

- French: complète

- German: die Ergänzung

- Italian: complemento

- Portuguese: complemento

- Spanish: complementa

------------

Report an incorrect translation @ wordofthehour.org/r/translatio

We need your help!! Help us improve our translations. :)

We rely on community members to help us improve our…

wordofthehour.org
WordofTheHour

#complement : the quantity or number required to fill a thing or make it complete

- French: complète

- German: die Ergänzung

- Italian: complemento

- Portuguese: complemento

- Spanish: complementa

------------

Report an incorrect translation @ wordofthehour.org/r/translatio

We need your help!! Help us improve our translations. :)

We rely on community members to help us improve our…

wordofthehour.org