#fattyacid

Mitochondrial morphology controls #fattyacid utilization by changing CPT1 sensitivity to #malonyl-#CoA

Orian Shirihai, Nika Danial and coworkers show that #mitochondrial fragmentation increases beta-oxidation and cellular #lipid #metabolism via de-repressing #CPT1
https://www.embopress.org/doi/10.15252/embj.2022111901

#Sirt6 control of #EndothelialCell #FattyAcid transport links #Diabetes microvascular dysfunction with #HeartFailurewithPreservedEjectionFraction #HFpEF

EC Sirt6->
H3K9ac PPARγ promoter
CD36,FABP4/5
Heart Lipid

Dr. Zheng Gen Jin lab Circ Res 2022
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318988

Full paper out now:

#FattyAcid profiles of more than 470 marine species from the Southern Hemisphere

http://doi.org/10.1002/ecy.3888