#lithium
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Reporterre
La course au lithium assoiffe les paysans boliviens
https://mcinformactions.net/la-course-au-lithium-assoiffe-les-paysans-boliviens
#Bolivie #lithium #eau
Le miniventilateur portable, une maxi-aberration écologique
> Dans les transports en commun et aux terrasses des restaurants, ils sont partout cet été. Mais les miniventilateurs en plastique sont une catastrophe écologique, avec leur acheminement depuis l’Asie et leur durée de vie limitée.
https://reporterre.net/Le-miniventilateur-portable-une-maxi-aberration-ecologique
#Pollution #Plastique #Lithium #Cobalt #Aberration_écologique #FdC #RevueDePresse
@docjosiahboone
Das Schlußwort im Artikel fasst es gut zusammen: "..dass ein Zuviel die Funktion von Schilddrüse und Nieren stört, bis eben zur chronischen Vergiftung. Sollte dieses Thema weiter erforscht werden? Natürlich. Kann man das Verbot von Lithium als Nahrungsergänzungsmittel für den Niedergang der Demokratie verantwortlich machen? Sicher nicht. Statt Menschen einzureden, sie bräuchten Lithium, sollte man besser dafür eintreten, dass die psychiatrische und psychotherapeutische Versorgung der Bevölkerung gesichert ist. Das wurde auf dem FPÖ-Symposium nicht besprochen."
https://archive.is/vYYpV
Derzeit läuft in Sachsen ein Forschungsprojekt zum Zusammenhang zu Suizidraten und #Lithium im Grundwasser.
https://www.uniklinikum-dresden.de/de/das-klinikum/kliniken-polikliniken-institute/psy/forschung-und-lehre/forschungsbereiche-1/suizidforschung/aktuelle-forschungsprojekte/zusammenhang-zwischen-lithiumgehalt-im-trinkwasser-und-suizidraten-in-sachsen
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Fragment EenVandaag, NPO Radio 1:
'Onderzoek met lithium tegen Alzheimer brengt nieuwe inzichten'
"Lithium en de ziekte van Alzheimer worden al tientallen jaren met elkaar in verband gebracht. Nieuw onderzoek van de Harvard University laat zien dat een tekort aan lithium Alzheimer kan veroorzaken en het heeft daarnaast aangetoond dat een speciale soort lithium beschadigingen in de hersenen bij muizen kon herstellen. Maar wat zegt dit?"
#gezondheid #Alzheimer #lithium #LithiumOroraat #LithiumTekort
Lithium en de ziekte van Alzheimer worden al tientallen…
NPO Radio 1'Oud middel biedt nieuwe hoop in strijd tegen Alzheimer: wetenschappers ontdekken beschermende werking van lithium'
"Wanneer muizen een lithiumarm dieet kregen, ontwikkelden hun hersenen ontstekingen en andere tekenen van versnelde veroudering. Bij muizen die genetisch gevoelig zijn voor Alzheimer, zorgde een tekort aan lithium bovendien voor een snellere opstapeling van amyloïde plaques, typisch voor Alzheimer, en sneller geheugenverlies."
"Omgekeerd bleek dat muizen beschermd werden tegen Alzheimer-gerelateerde hersenveranderingen als hun lithiumniveau op peil bleef. De onderzoekers brachten ook in kaart hoe lithium in het brein werkt: schadelijke eiwitophopingen lijken lithium te “vangen”, waardoor opruimcellen (microglia) minder goed hun werk kunnen doen. Een bepaald type lithium, lithium orotaat, blijft wel beschikbaar in het brein en draaide zelfs enkele alzheimerachtige hersenschade om bij muizen."
"Het onderzoek bouwt voort op eerdere studies. Zo bleek uit een Deense studie dat mensen in regio’s met meer lithium in het drinkwater minder vaak dementie ontwikkelen, en Britse data wijzen uit dat patiënten die lithium kregen, een lager risico op Alzheimer hadden."
"Toch waarschuwen experts dat deze resultaten niet betekenen dat we nu massaal aan de lithiumsupplementen moeten: de gebruikte doseringen bij muizen lagen ongeveer duizend keer lager dan de therapeutische doseringen voor stemmingsstoornissen, en het effect bij mensen is nog niet bewezen. De belangrijkste bronnen van lithium in de voeding zijn groene bladgroenten, noten, peulvruchten en bepaalde specerijen, een dieet dat al bekendstaat als gunstig voor de hersenen."
Lithium biedt mogelijk bescherming aan het verouderende…
hln.be'Breakthrough study finds deficiency of this common nutrient could contribute to Alzheimer’s'
"Scientists from Harvard Medical School found that lithium loss in the human brain is one of the earliest changes leading to Alzheimer’s, while in mice, a similar lithium depletion accelerated memory decline."
"Researchers also showed that a new type of lithium compound – lithium orotate – can avoid capture by amyloid plaques and restore memory in mice."
"The latest findings with lithium orotate, however, needs to be confirmed in humans via clinical trials."
#health #Alzheimers #AlzheimersDisease #lithium #LithiumDeficiency #LithiumOrorate
Scientists find new compound that could reverse memory…
The Independent'Scientists link brain lithium loss to early Alzheimer’s changes'
"low-dose lithium orotate in mice can protect against memory loss and brain damage"
"They found that reduced endogenous lithium contributes to early pathological changes in the progression of the disease, while restoring lithium levels with lithium orotate prevents brain damage and memory loss in mouse models, suggesting a potential preventive and therapeutic strategy for Alzheimer’s."
"lithium supplementation, especially with lithium orotate, restored brain lithium levels and prevented many Alzheimer’s disease-related changes, including plaque buildup and inflammation. Lithium orotate was more effective than lithium carbonate at elevating lithium in the non-plaque brain tissue and did not show evidence of toxicity at the low doses used. By contrast, lithium carbonate showed greater sequestration in amyloid plaques and did not significantly improve pathology at the same low dose."
"In laboratory tests, lithium orotate also showed weaker binding to amyloid-β proteins, which may allow it to better evade sequestration by plaques and improve its brain distribution. Overall, the results suggest that reduced lithium levels in the brain may contribute to the development of Alzheimer’s disease, and restoring physiological lithium levels, especially with lithium orotate, could help protect against cognitive decline and Alzheimer’s pathology."
"Notably, lithium levels were consistently lower in the brains of humans with Alzheimer’s disease, aligning with mouse model findings"
#health #Alzheimers #AlzheimersDisease #AD #lithium #LithiumOrorate
"Importantly, the study demonstrated that a low-dose lithium orotate treatment, keeping lithium in the physiological range, was effective in reversing the pathology of the disease in mice without detectable toxicity, addressing a major concern of standard lithium therapies."
Researchers have discovered that naturally occurring…
News-Medical'Lithium deficiency and the onset of Alzheimer’s disease'
"The earliest molecular changes in Alzheimer’s disease (AD) are poorly understood. Here we show that endogenous lithium (Li) is dynamically regulated in the brain and contributes to cognitive preservation during ageing."
"Replacement therapy with lithium orotate, which is a Li salt with reduced amyloid binding, prevents pathological changes and memory loss in AD mouse models and ageing wild-type mice."
"In humans, Li is used in psychiatry for the treatment of bipolar disorder at a dose range that raises levels in serum to approximately 1,000 times the endogenous level. We found that in normal ageing mice, low micromolar levels of endogenous Li preserve cognitive function, reduce inflammation and suppress Aβ generation. In AD mouse models, endogenous Li protects against amyloid deposition, tau hyperphosphorylation, neuroinflammation and loss of synapses, axons and myelin."
"This observation is consistent with a population study in Denmark that found a significant inverse correlation between Li levels in local drinking water and the incidence of dementia"
"In two initial trials, Li treatment did not improve cognitive function, but in three subsequent trials, Li at lower concentrations (0.25–0.5 mEq l−1 in serum) reduced cognitive decline. A limitation of these clinical trials might have been the use of Li salts with high levels of amyloid binding. We have characterized a Li salt, lithium orotate, with reduced binding that can bypass amyloid sequestration in AD mouse models"
"It is encouraging that toxicity could not be detected following long-term treatment of ageing mice with a low dose of LiO."
https://www.nature.com/articles/s41586-025-09335-x
#health #Alzheimers #AlzheimersDisease #AD #lithium #LithiumDeficiency #LithiumOrorate
Lithium has an essential role in the brain and is deficient…
Naturehttps://www.europesays.com/fr/306250/ La promesse inattendue du lithium caché dans le cerveau pour guérir de la maladie d’Alzheimer #alzheimer #cerveau #CorpsHumain #étude #FR #France #Health #Lithium #maladie #neuro #Santé
@muninn@social.coopInteresting study in Nature for people with a family history of #dementia & #Alzheimers, #ApoE4 carriers, etc.
This doesn't come out of nowhere, researchers have previously noted somewhat lower dementia rates in areas with a lot of lithium in the water.
Lithium deficiency and the onset of Alzheimer’s disease
https://www.nature.com/articles/s41586-025-09335-x
10.1038/s41586-025-09335-x
Lithium has an essential role in the brain and is deficient…
NatureThe common household items sparking explosive lithium fires
By Mya Kordic
The number of fires caused by exploding lithium-ion batteries so far this year is almost double the number of fires for the entire 2020.
https://www.abc.net.au/news/2025-08-08/lithium-batteries-sparking-house-fires-wa/105629032
The number of fires caused by exploding lithium-ion…
ABC Newshttps://www.nature.com/articles/d41586-025-02471-4 New hope for #Alzheimer’s: #lithium supplement reverses memory loss in mice
Studies in rodents and humans suggest that low levels…
www.nature.comCalifornia Start-Up Will Buy Assets of Bankrupt Swedish Battery Maker - Lyten will acquire German and Swedish factories built by Northvolt, which declared bankru... - https://www.nytimes.com/2025/08/07/business/lyten-northvolt-ev-batteries.html #factoriesandmanufacturing #electricandhybridvehicles #sulfurandsulfurcompounds #lithium(metal) #sanjose(calif) #bankruptcies #automobiles #northvoltab #start-ups #batteries #germany #poland #sweden #lyten
Lyten will acquire German and Swedish factories built…
The New York Times
@Nonya_Bidniss@infosec.exchangeNeuroscientists analyzed the brain tissue of people with Alzheimer’s disease and found that the sticky plaques of amyloid protein that are a hallmark of the disease had high concentrations of lithium, while it was depleted in the rest of the brain. The researchers hypothesized that lithium naturally exists in our bodies as part of a carefully calibrated ecosystem of metal ions. In Alzheimer’s disease, amyloid plaques sequester this freely available lithium, preventing it from being used in various neural processes. This process could lead to downstream symptoms of Alzheimer’s, like memory loss and cognitive decline.
Researchers then identified a compound called lithium orotate that can bolster natural levels of lithium without getting trapped by amyloid plaques. In studies of adult mice engineered to have Alzheimer’s-like symptoms, adding a low dose of lithium orotate to their drinking water prevented the development of plaques and completely reversed memory loss in mice. “It seems to somehow turn back the clock,” the paper’s senior author, Bruce Yankner, told The Boston Globe.
Scientists hope that this paper will breathe new life into the search for a cure for Alzheimer’s disease and open up new questions about the role of lithium in the brain. “[Lithium] powers our phones, laptops, and electric vehicles,” Yankner tells Science. “My guess is the brain might have utilized this unique electrochemistry before we did.” #alzheimers #lithium #neuroscience #medicine
Paywall https://www.science.org/content/article/could-lithium-stave-alzheimer-s-disease
Paywall https://www.bostonglobe.com/2025/08/06/metro/alzheimers-treatment-harvard-lithium-deficiency-plaques/
Paywall https://www.nature.com/articles/d41586-025-02471-4
No paywall https://archive.is/LB5Ps
Ein Lithiummangel im Gehirn könnte der „Zündfunke“ sein, der Alzheimer auslöst und vorantreibt. Es gibt jedoch ein Lithium-Präparat, das dies verhindert und sogar rückgängig macht – zumindest bei Mäusen. #Alzheimer #Lithium #Demenz #Gehirn
https://www.scinexx.de/news/medizin/ist-lithiummangel-der-zuendfunke-fuer-alzheimer/
Schlüsselfunktion: Ein Lithiummangel im Gehirn könnte…
scinexx | Das WissensmagazinResearchers led by Bruce A. Yankner, prof of genetics, neurology at Harvard Medical School reported that they were able to reverse #Alzheimer’s in mice, restore #brain function w small amounts of compound #lithium enough to mimic metal’s natural level in the brain. “The obvious impact is that because lithium orotate is dirt cheap, hopefully we will get rigorous, randomized trials testing this very, very quickly”...https://www.msn.com/en-us/science/biochemistry/research-on-reversing-alzheimer-s-reveals-lithium-as-potential-key/ar-AA1K1DXW #healthcare #medicine #research
Notable observation: A new Nature study links #lithium deficiency to Alzheimer’s.
Lithium has an essential role in the brain and is deficient…
Nature
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