PLOS Biology

#Cilia are essential for early embryonic L-R patterning, but what about later? Tissue/time-specific cilia inhibition in mouse embryos reveals a cell-autonomous role for cilia in #NeuralCrest-mediated #craniofacial & body wall closure defects #PLOSBiology plos.io/3NqvcHn

Hao Yin

#Cohesinopathy

BRD4 (acetyl lysine reader)-NIPBL (cohesin loading ) complex is critical to #NeuralCrest differentiation into #SmoothMuscleCell

BRD4 depletion->⏬#GenomeFolding+loop extrusion

BRD4 in #AorticAneurysm?

Dr. Rajan Jain lab Nature Genet 2021
nature.com/articles/s41588-021

Mike Piacentino

Check it out (and please boost this)!

We are recruiting two full time researchers to study #lipids in #neuralcrest #devbiol! Interested in joining us as we build an engaging, welcoming, and inclusive group at
Johns Hopkins? Apply now!

Research Technologist (jobs.jhu.edu/job/Baltimore-Res)
Research Specialist (jobs.jhu.edu/job/Baltimore-Res)

Research Technologist

Research Technologist

jobs.jhu.edu
AIneurolab

Alas, a very windy and wet day in Halifax, Nova Scotia today. Perfect for doing whole mount embryo immunostaining experiments, organoid differentiation assays, and correcting term papers. Also reviewing, meeting guest lecturers, meetings…all the things we do at the university! #neurobiology #developmentalbiology #DevBio #cytoskeleton #neuralcrest

Anestis Tsakiridis

Latest work from our lab examining the interface between tumour initiation and embryonic cell fate decisions: a great collaboration with Florian Halbritter, spearheaded by Ingrid Saldana-Guerrero and Luis Montano-Gutierrez (all Mastodon-less, I think) #devbiol #Devbiol #stemcell #cancer #neuroblastoma #neuralcrest
biorxiv.org/content/10.1101/20

Neuroblastoma-associated chromosomal aberrations drive cell identity loss in human neural crest via disruption of developmental regulators

Early childhood tumours are thought to arise from transformed…

www.biorxiv.org