#PAXLOVID

Your govt at work:Paxlovid Medicare with Medigap Insurance: $226. With GoodRX: $1,500. Before the Covid crisis was declared over: Nil. Feels like they'd just assume we die.

Government efficiency, my ass.

#Covid #COVID19 #Paxlovid #Mask #Health #Medicare #Author #Writer #WritersOfMastodon #WritingCommunity

· People with recent COVID-19 at higher risk for other viral and bacterial infections
· A 15-day course of #Paxlovid did not “significantly improve health outcomes in participants with #LongCOVID
· 2. study showed that Paxlovid taken within 5 days of infection with COVID-19 did help with the acute phase of COVID-19 in children
· Rapamycin, a drug used for organ transplants, may help alleviate symptoms of myalgic encephalomyelitis #MECFS

https://thesicktimes.org/2025/04/08/research-updates-april-8/

#ResearchUpdates #COVID19

#vipintukur on X wrote:

Researchers have developed an oral antiviral drug candidate for #COVID19 that could overcome major limitations of #Paxlovid, currently the most prescribed oral treatment.

https://threadreaderapp.com/thread/1907829320304791834.html

"Covid Protocol" goes like this:

Sick person isolated in room, block door with towel, only come through rest of house with #N95 briefly. Tray table outside door for food drop off. Disinfect everything.

#paxlovid ASAP for sick, lower #covid damage.

Heater off, open windows, box fans in windows to make positive pressure in main house, negative pressure in sick room, dumping sick air out bedroom window.

Constant air flow.

Yes, we fucking freeze.

All-clear when RAT clear, and nobody sick.

"There are over 200 different symptoms that can appear in any different combination. And then the other piece about it is there are about six different mechanisms of what can be causing long COVID. So everyone has in common COVID as the thing that started their long COVID.

However, there are so many different physiological things going wrong in different people with long COVID, they might require different treatments."

"There are actually a lot of great trials going on [...] one looking at mitochondrial dysfunction is Rapamycin, which David Petrino’s group is running."

"There’s a few looking at immunomodulation with JAK inhibitors, both the Baricitinib trial by Wes Eli’s group and another JAK inhibitor trial that’s starting at Harvard. Another immunomodulation option is IVIG, which is being run by the NIH RECOVER consortium. This one’s tricky because it’s not super scalable. You have to get the antibodies from people and then infuse them into other people"

"And then the other mechanism that’s being looked at a lot now is viral persistence, both through a few different monoclonal antibodies trials– Michael Peluso’s, funded by the Patient Led Research Collaborative. Nancy Klimas is just starting one funded by the Schmidt Initiative for Long COVID and the state of California. And then there’s another one in Italy that’s funded by industry, all looking at monoclonal antibodies. And then the last viral persistence one is also being run by the Petrino group on Truvada, which is an HIV antiviral."

https://www.sciencefriday.com/segments/paxlovid-long-covid/

@patientled

#SARSCoV2 #LongCovid #paxlovid #LC #PwLC #PASC #COVID #COVID19

@MaksiSanctum thank you for this information, last year I asked my doctor if I should take this or #Paxlovid if I tested positive and he said paxlovid, but the box I have expired in the spring of 2023 I think, and now insurance doesn’t cover it so I’m not sure if I could get a fresh one. I’m going to drop this link in the portal for him.

After 5 years of fighting to not get #COVID, wearing masks, not eating indoors, etc. I finally tested positive after my dad’s funeral.

I’ve had every vaccine and booster and so far the symptoms are very mild. 72 hours after exposure:
- Chills; but no fever.
- Body aches
- Slight soar throat
- Little appetite

Not a candidate for #Paxlovid even with #UC since I’m not on an immunotherapy.

I’m hoping it passes quickly.

#WearAMask #GetBoosted #VaccinesWork #COVIDIsntOver #COVID19

Paxlovid hilft einigen Patienten mit LongCovid. Macht Sinn, denn wir wissen, dass das Virus bei viel mehr Menschen im Körper bleibt, als wir dachten.

Die Packung kostet in der Schweiz etwa 1000 Franken. Wird meist nicht durch die Versicherung übernommen. Die Ärzte verschreiben es aber auf Wunsch wenn man einen positiven Schnelltest und LongCovid als Vorerkrankung angibt. (Nen bissle telefonieren, vielleicht verschreibt es erst der Dritte)

https://www.nature.com/articles/s43856-024-00668-8

#paxlovid #longcovid #corona

Omg.

An elderly family member is in the ER for a fall. This person is 83, has Parkinson's Disease, and is a lifelong smoker. While in the ER, they tested positive for covid.

Their caregiver requested #Paxlovid and reports, "The doctor that was here was like we don't prescribe that and it doesn't work. That is exactly what she said."

?!?!

1/2

#CovidIsNotOver

@Leefromphilly I am glad that you are recovering!

You said, "[COVID] never went into my lungs; if it had, I definitely would have gone the #paxlovid route."

Unfortunately, Paxlovid doesn't work like that. It's a *preventative* against severe disease: you have to take it as soon as you know you have COVID, before you know how bad the illness is going to get. :-(

Extended course of Paxlovid in patients with long COVID had mixed results in very small study. Paper discusses each of 13 cases at length. Some of these patients were taking a large number of other meds and supplements. #LongCOVID #Paxlovid https://www.nature.com/articles/s43856-024-00668-8

Final (hopefully!) #covid update.

I have a lingering cough and stuffy nose to remind me of my recent – and only 2nd – bout of Covid. My first 2 1/2 days of fever were pretty bad. I didn’t get Paxlovid because of knowing of several people who took it and then relapsed. Just my own personal decision and experience. Fortunately, it never went into my lungs; if it had, I definitely would have gone the #paxlovid route.

I’m so glad I got my booster shot in November! Could’ve been much worse…

#mask

Extended Paxlovid May Relieve Long Covid Symptoms
https://neurosciencenews.com/paxlovid-long-covid-28314/

#COVID #LONGCOVID #PAXLOVID #KEWLNEWS #PRESS

Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with hospitalizations, deaths, & CV events.
@DavidJoffe64 at X

https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346

Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with hospitalizations, deaths, & CV events.
@DavidJoffe64 at X

https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346

Meine Partnerin ist wieder #Corona positiv. Nach 12 Tage und insgesamt 10 Tagen Behandlung mit #Paxlovid

Sie bleibt also in der Gästewohnung. So ein misst.

Seid also vorsichtig, wenn ihr euch auch isoliert. Das Virus bleibt lange im Körper.

@maggiejk

Yeah they say it works, but it works as people who take it are special. But they don’t give a reason what’s so special about them?

It’s mainly politicians and educated people with enough money who had and have access to #paxlovid.
I guess that’s what they meant?

Negativ, im Rachen und in der Nase. Keine Symptome. Bin #Corona wohl noch mal entkommen. Danke Impfung & Betadine

Meine Partnerin war dank #Paxlovid nach 3 Tagen schon negativ. Bleibt aber in Quarantäne und nimmt das Medikament für 10 Tage. Sie hatte letzten Freitag erste Symptome war also seit Donnerstag ansteckend.

“The incubation periods of COVID-19 caused by the Alpha, Beta, Delta, and Omicron variants were 5.00, 4.50, 4.41, and 3.42 days, respectively.”
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2795489

#Paxlovid ist super. Meine Partnerin hat immer noch kein Fieber. Sie hat etwas Kopfweh und ihre Nase läuft. Der letzte Booster war im Juli.

Ich bin weiterhin negativ, hab Spass mit Betadine und grad froh das es Newgene Tests noch im fünfer Pack für unter 10 CHF gibt.

Ich fand es süss, als Sie dachte: Ein teures Medikament kostet 100 Franken. Paxlovid ist 1000 bis 1500 CHF wenn die Kasse es nicht trägt. In der CH gilt, Gesundheit kostet.

#Corona

Just checked, and in 2025 no #Medicare #PartD provider will cover #Paxlovid for #COVID19. Nor will the government subsidize it as it did before. We'll now see the virus burn through the vulnerable elderly population as never before. Humanity's handling of #SARSCoV2 has been so incompetent that #H5N1 stands to be truly devastating.