#SarsCoV2

¿Recuerdan el brote de hepatitis en niños que apareció en Europa, Estados Unidos y partes de Asia en la primavera de 2022? Muchos no creyeron a los que afirmaron que era causado por #COVID19.

Pues parece que sí fue el #SARSCoV2.

¡Qué sigan los estudios!

https://www.zmescience.com/medicine/that-2022-hepatitis-outbreak-in-kids-it-was-apparently-covid/

¿Recuerdan el brote de hepatitis en niños que apareció en Europa, Estados Unidos y partes de Asia en la primavera de 2022? Muchos no creyeron a los que afirmaron que era causado por #COVID19.

Pues parece que sí fue el #SARSCoV2.

¡Qué sigan los estudios!

https://www.zmescience.com/medicine/that-2022-hepatitis-outbreak-in-kids-it-was-apparently-covid/

Impact of #SARSCoV2 on the male reproductive tract: insights from semen analysis and cryopreservation | Journal of Assisted Reproduction and Genetics | #COVID19

https://link.springer.com/article/10.1007/s10815-024-03321-4

New US research:

Identifying commonalities & differences between EHR representations of #PASC & ME/CFS in the RECOVER EHR cohort

https://www.nature.com/articles/s43856-025-00827-5

"These findings suggest symptom management approaches to these illnesses could overlap"

@mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @longcovid
#LongCovid #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

Und das in den verschiedensten Bereichen. Die bekanntesten sind wohl #Klimawandel und #Corona #SARSCoV2, also Gesundheit.

Das tragischste an der bitteren Wahrheit ist, dass ein Nicht-Anerkennen oder gar Leugnung immer ein Resultat hat: Leid.

#LongCovid, #mecfs, #Hitzetot, etc

Ich bin #mütend

Reiterating: negative pressure zones completely contained aerosolized virus. They could not detect ANY virus in the air of areas that were upstream of negative-pressure COVID-19 care!

So yes, home isolation protocols that include negative pressure zones absolutely are well founded!

Folks who have worked in or around remediation that uses the same principle might not be surprised.

https://www.sciencedirect.com/science/article/pii/S0021850225000643

#SARSCoV2 #COVID #COVID19 #pandemic

This preprint seems so good! [edit: pre-proof not pre-print, it has been peer reviewed and the data passed muster, but might have formatting, grammar, and spelling tweaks]

goals were: a) to detect viral load in indoor air in different areas and floors of a separate COVID building in a hospital [...], b) to evaluate the effect of an air-cleaner in the reduction of viral load in the presence of patients, and c) to examine the correlation between viral presence in the air and particle matter burden.

their methodology is making me happy!

Their system separated aerosols into > 2.5 μm, 1.0 to 2.5 μm, 0.5 to 1.0 μm, 0.25 to 0.50 μm, and < 0.25 μm, and found

SARS-CoV-2 was detected in all different fractions and the highest viral loads were detected at stages A (> 2.5 μm) and B (1 - 2.5 μm).

however this was in open-window conditions, ie. low CO2 and higher airflow; sampling with the same equipment in households, they found

the highest amount was detected in Stage 4 (0.25 - 0.5 μm)

The data is mostly PCR but they did do some sequencing, and positively confirmed the dominant variants were stable through the study, and not confounding.

Note the air cleaner was a "Airocide (APS GCS-25 model) air purifier" which uses "photocatalytic oxidation technology" as well as 254nm UV, with no HEPA or other mechanical filter.

Also, this is vindicating for those of us pleading with folks to not immediately de-mask in the hallway:

the highest concentration was detected in COVID clinic rooms displaying a high peak of 1123 copies/m3, whereas at the corridor area showed 481 copies/m3

Also highly of note, they could not detect any virus in the areas that were upstream of negative-pressure COVID-19 care. So yes, home isolation protocols that emphasize negative pressure zones absolutely are well founded!

https://www.sciencedirect.com/science/article/pii/S0021850225000643 via https://aus.social/@Sidherian

#SARSCoV2 #COVID #COVID19 #COVIDIsNotOver #CovidIsAirborne #AirborneAware #CovidCompetent #PublicHealth #CleanAir

These findings support the “Broken Bridge Syndrome” hypothesis, positing that structural disconnections between the brainstem and cerebellum contribute to PCS [Long COVID] symptomatology. Furthermore, we propose that chronic activation of the Extended Autonomic System (EAS), encompassing the hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system, may perpetuate these symptoms

In this high quality brain volume data,

Significant volume loss was observed in the superior cerebellar peduncle (SCP) in LC patients compared to healthy controls (LC: 219.74 mm³ vs. controls: 347.03 mm³, p < .001, Hedges’ g = 3.31). Furthermore, reduced volumes were evident in the dorsal raphe (DR) and midbrain reticular formation (mRt) (p < .001)

It was not metabolism-marker scanning, but volumentric, so they were able to capture:

Three-dimensional reconstructions revealed deformities in the 4th ventricle and cerebellar peduncles, suggesting impaired cerebrospinal fluid dynamics [...] Importantly, these volume reductions and FA changes correlated with motor deficits,
proprioceptive dysfunction, and autonomic dysregulation

TLDR?

Our findings reveal significant structural and functional alterations in the brainstem and cerebellar peduncles of LC patients

https://www.medrxiv.org/content/10.1101/2025.04.08.25325108v1

via https://zeroes.ca/explore/links

#SARSCoV2 #COVID #COVID19 #COVIDIsNotOver #AirborneAware #CovidCompetent

Is widespread reluctance to fully acknowledge airborne transmission of #SARSCoV2 because of the implications for governments, businesses, education facilities, and healthcare?
This virus is 'so' still moving in the air!
Important to act where possible with a vaccine booster, improved ventilation, and wearing a mask, wherever appropriate.

Is the reluctance [by WHO?] to fully acknowledge airborne transmission of #SARSCoV2 because of the implications for governments, businesses, and healthcare services?
The virus is still moving in the air so important to take actions such as enhancing ventilation or wearing masks wherever appropriate.

From Australia:

"WEHI researchers have developed a drug compound that can protect mice from contracting long COVID symptoms.

The world-first study also found the compound can treat acute #COVID with better efficacy than Paxlovid"

https://www.eurekalert.org/news-releases/1079816

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
@auscovid19 #auscovid19

From Russia:

B Cell Dynamics and Transitional B Cells in Long COVID

Image is from latest Science for ME weekly update

https://www.mdpi.com/1467-3045/47/4/245

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

From France:

Reorganization of brain connectivity in post-COVID condition: a 18F-FDG PET study

Image is from latest Science for ME weekly update

https://ejnmmires.springeropen.com/articles/10.1186/s13550-025-01217-7

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19 #auscovid19

"Only 25% patients referred to the Pan-London #PostCOVID service were attending school at least half of the week, emphasising the functional impact of #PCC "

Image is from latest Science for ME weekly update

https://www.jahonline.org/article/S1054-139X%2825%2900066-7/abstract

#LongCovidKids #LCKids @longcovid
#LongCovid #PASC #PwLC #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19

From the US:

Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of #SARSCoV2 Infection: A RECOVER-EHR Cohort Study

Image is from latest Science for ME weekly update

https://www.medrxiv.org/content/10.1101/2025.03.28.25324858v1

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19 #auscovid19

UPDATED: #Ontario #SARSCoV2 variants.

Only 38 samples for 3/23 - 3/29

Of those,
XEC.*: 29% ( 36.4%; 28.3%)
LP.8.1.*: 50% † ( 32.6%; 22.9%)
MC.10.1.*: 5.3% ( 8.5%; 10.8%)

https://ratnegative.tumblr.com/ONVariants #COVID19

----------

Of the samples collected in Ontario on these weeks, the prevalence of each of these significant variants/lineages are as follows:

- 3/23 - 3/29 - (38 samples; 4% threshold)
• XEC.* (incl. XEC.2, ".4): 29%
• LP.8.1.* (only LP.8.1.1, NY.6 ctd.) †: 50%
• MC.10.1.* (incl. MC.10.1.6): 5.3%

† 1 LP.8.1 sample counted as KP.1.1.*

- 3/16 - 3/22 -
• XEC.* (incl. XEC.2.*, ".4, ".5, ".8, ".9, ".11.*, ".12, ".14, ".18): 28.9%
• LP.8.1.* (incl. LP.8.1.1, ".8.1.3, NY.3): 32.6%
• MC.10.1.* (incl. MC.10.1.5, ".10.1.6): 8.5%

X.X.* in text = X.X & descendants.

X.X.* in graph = all descendants of X.X, except for ones with own segment of week’s bar.

@Ashedryden sure:

be well rested and less stressed. Really! Immune systems perform better when the organism is well-rested, and worse when under stress conditions. Literally calm your system beforehand with meditation if you can?
have your vitamins. Results for vitamins D and C vary from "no effect" to "protective" (https://pmc.ncbi.nlm.nih.gov/articles/PMC9864223/ for example), with clear evidence that low vitamin D can down-modulate immunity. Especially important for PoC in northern climes, folks who don't work outdoors, and similar. Maybe start supplementing vitamin D (through sun exposure or pills) a week+ ahead?
nasal sprays and mouthwashes. There is evidence for both xylitol and iota-carrageenan giving protection against SARS-CoV-2. A nice review with links to actual research from this past summer: https://integrativewomenshealthinstitute.com/how-to-prevent-long-covid-summer-2024-update/
UV light disinfection, aka Germicidal Ultraviolet. This is harder to access as most installations are for industry, but if you have time and energy perhaps you can DIY it or find a supplier.
explicitly say "And if you want to come but are feeling sick, let us know, and we'll drop off a get-better goodie basket and a little gift!" or similar, so folks who are ill have motivation to not come.

You've already said you will ventilate and filter. Add more filters? HEPA is great but Corsi-Rosenthal boxes with MERV-13 filters are also highly effective, relatively inexpensive, and if made with computer fans, very very quiet. They can be totally DIY - there's even a song about it https://www.youtube.com/watch?v=5XS-7vgThfQ !!! - , and various sellers have them available as kits or prefabbed, too.

Less likely to be useful:

vaccinate 2-3 weeks prior to be at peak vax-induced immunity before waning
PlusLife or RAT testing at the door
free mask basket at the door. You sound perhaps willing to use an N95 but you indicated your guests wouldn't.

I hope some of those help! None of them will guarantee no infection, but when one must face such situations, the odds can be improved.

#SwissCheeseModel #AirborneAware #CovidCompetent #CovidConscious #COVIDcautious #SwissCheeseDefence #SwissCheeseDefense #DefenseInDepth #DefenceInDepth #COVIDIsNotOver #SARSCoV2 #COVID #COVID19 #CovidIsAirborne

AMA Update from Dr. Akiko Iwasaki, Sterling Professor of Immunobiology, Yale

ad-free or original

Common manifestations of Long COVID [which] are not very well discussed, and many physicians may not be aware of:

Internal tremor ... Over one third of Long COVID patients report experiencing internal vibration or tremor sensations that are without visible external signs

Postural orthostatic tachycardia syndrome (POTS)

Post-Exertional Malaise (PEM)

Hormonal dysregulations

Sleep disturbance

If you're a physician are these surprising to you? Are the four identified endotypes surprising?

via https://zeroes.ca/@trendless/114304265960580458

Calculate your personal #longCOVID risk

https://www.uq.edu.au/news/article/2024/07/calculate-your-personal-long-covid-risk

The calculator:

https://corical.immunisationcoalition.org.au/longcovid

#sars2 #sarscov2 #covid19

3/
Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with #longCOVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial

Image is from latest Science for ME weekly update

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2825%2900073-8/abstract

@longcovid
#PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19