#Senolytic
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SenMayo
A 125-gene set (15 studies) for #Senescence/#SASP in Bone/Bone marrow/Adipose/Brain...
#Senolytic readout
vs GenAge & CellAge
MIF as a key SASP gene!
Dr. Dominik Saul, Joshua Farr & Sundeep Khosla labs Nature Comms 2022
https://www.nature.com/articles/s41467-022-32552-1
Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.058794
Elated to be selected as a recipient of @GileadSciences@twitter.com Liver Disease Scholar 2022
#LiverDisease #Senolytic
#Senescence #ImmuneSurveillance
Next-gen #Senolytic
#ImmuneCheckpointBlockade activates CD8+ T cytotoxicity against (inflammed
) PD-L1+ senescent cells->
adverse phenotypes in
#Aging+#NASH
Dr. Yoshikazu Johmura & Makoto Nakanishi labs Nature 2022
https://www.nature.com/articles/s41586-022-05388-4
