PastelBio

RT @: Looking for an interesting read on a lazy Sunday? Check out our #preprint on a new #proteomics workflow for analysis of Tyr #sulfation. Novel sTyr proteins include both glycan and protein sulfotransferases. @Pseudoenzyme @andy___jones @c4pr_liv

Rhyothemis

Carbon disulfide & aging

Last year the Longevity Prize offered a $20k Hypothesis Prize. I submitted something since I figured its probably better odds than the lottery. The submission was due at end of last year, but so far no updates to the page & no announcement of a winner. Whatever.🤷

I was left completely drained by the effort - but I learned a lot of fascinating things.

Here's my submission:
docs.google.com/document/d/155

#Aging #health #neuroscience #GutMicrobiome #CS2 #sulfation

Rhyothemis

sulfation & longevity (worms)

“These sulfated steroid hormones, probably altering neurotransmission, produce an increase in longevity, through common factors to germline-less animals. The fact that the enzymes involved in the sulfate modification of steroid hormones ... are expressed in sensory neurons suggests that alteration the sulfated state of hormones may acts in the integration of environmental cues ...with the reproductive status..." doi.org/10.1038/s41467-020-202

#aging #longevity #sulfation

Dave Fernig

A short account of a recent paper led by Steve Butler on the development of a europium (III) radiometric sensor for PAP/PAPS. Of interest to #GlycoTime #Sulfation #Sulfotransferase #HighThroughput ferniglab.wordpress.com/2022/1

Real-time sulfotransferase assay

Ferniglab Blog