#tcells
These are public posts tagged with #tcells. You can interact with them if you have an account anywhere in the fediverse.
Dietmar Zehn, Professor of Animal Physiology and #Immunology, and his team showed that the body prepares itself for a severe course of illness even in the case of uncomplicated #infections by producing special #Tcells: http://go.tum.de/664167
A.Eckert
Even in the case of uncomplicated infections, the body…
www.tum.dehttps://www.europesays.com/uk/2551/ Female Hormones Trigger Pain Relief via Immune Cells #BrainResearch #estrogen #Health #ImmuneCells #neurobiology #Neurology #Neuroscience #pain #PainRelief #TCells #UCSF #UK #UnitedKingdom
Understanding Long COVID
Through CD8+ T Cell Responses
SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over two years
https://www.pnas.org/doi/10.1073/pnas.2411428121
See Also: Mast Cell Activation Episode
https://www.buzzsprout.com/2405788/episodes/15875307
#CD8 #TCells #LongCovid #Vaccines #Study #TwoYears #Immunity ##Durability
today I watched:
How Alzheimer's mutates the immune system | nature video
https://youtu.be/o_dbdhwNbig?si=P53kD4ckA45YXKRL
5 min. interview with David Gate on CXCR3 expressing peripheral T cells and Alzheimer disease.
~
I wonder if thiamine deficiency increases CXCR3 expression?
#2dayIwatched #Alzheimers
#NeurdegenerativeDiseases
#Tcells #BrainHealth
Surprise Discovery: Scientists Discover New Anti-Cancer Potential of Salt
https://scitechdaily.com/surprise-discovery-scientists-discover-new-anti-cancer-potential-of-salt/ #salt #cancer #Tcells #Immunology
Christina Zielinski and her team have discovered that…
SciTechDailyKnow your neighbours…
Spatial positioning determines tissue-resident memory T cell fate in the gut.
Marina Schernthanner covers work from Miguel Reina-Campos & colleagues. #preprint
#biology #immunology #intestine #TCells #bioinformatics #transcriptomics
Know your neighbors – spatial positioning determines…
preLights"Viral persistence and sustained immune activation are linked to Long Covid."
https://www.science.org/doi/10.1126/scitranslmed.adk3295
#LongCOVID #NotInYourHead #SARSCov2 #Virology #ChronicDisease #ViralInfection #ViralRNA #ImmuneCells #TCells #ViralPersistence
“This study represents a significant scientific breakthrough, as it shifts the paradigm in the understanding of MHC Class II peptides and their recognition by CD4+ T cells.”
One of the #SIBRemarkableOutputs 2023 
More: https://abcnews.go.com/GMA/GMA3/video/unusual-cancers-emerged-after-pandemic-covid-blame-110932851
SO CLOSE!!!
They’re so close to getting it
It’s inflammation
It’s only the vulnerable
There’s no excuse for this level of stupidity. NONE.
Saw a Tern post about 
accidents, & having been in one pretty crazy Vin Diesel one myself tipped off by a fender bender I didn’t fix months earlier… that metaphor analogy is something people will have to learn the hard way apparently
You can’t un-ring bells
#turbocancer #tcells #ImmuneDysregulation
#CovidIsNotOver #wearARespirator
A new article found that aggressive, late-stage cancers…
abcnews.go.com" The insights derived from this analysis do not only support a CD19 CAR T cell-mediated reset of the memory B cell compartment, but also the parallel inhibition of the interferon signature
in #monocytes and #Tcells of #SLE patients"
https://insight.jci.org/articles/view/179433
Striking that this apparently works better in getting rid of certain memory #Bcells than anti-CD20 antibodies.
Impressive new work by Moravec et al. in Nature Biotechnology, sadly not open source. "... a #HighThroughput personalized #TCR discovery pipeline ..." with which they "...identified dozens of CD4+ and CD8+ T-cell-derived TCRs with potent tumor reactivity, including TCRs that recognized patient-specific #neoantigens."
Researchers discovered that #tumors use a messenger substance to influence #immunecells in an early phase of the immune response. This could significantly improve #cancer immunotherapies: http://go.tum.de/368607
A.Eckert
Tumors actively prevent the formation of immune cells…
go.tum.deNew approach detects T cells in "cold" tumors, paves way for broader immunotherapy
https://www.news-medical.net/news/20240229/New-approach-detects-T-cells-in-cold-tumors-paves-way-for-broader-immunotherapy.aspx
#TCells
#Cancer
#ColdTumors
#Tumors
#Immunotherapy
#LaJollaInstituteForImmunology
#Neoantigens
Most cancers are thought to evade the immune system.…
www.news-medical.net
Researchers discovered that #Bcells play an active role in teaching #Tcells not to attack the body itself. If the "training" fails, #autoimmunediseases such as #neuromyelitis can develop: http://go.tum.de/562972
J. Böttcher, T. Korn
Russia loses tenth plane in 10 daysby newsweek
EUROPE SAYS
@nemo@mas.toBystander activated #CD8 #Tcells mediate #neuropathology during #viral infection via antigen-independent #cytotoxicity
>90% of #TCR sequence diversity is generated by TdT-mediated nucleotide addition, but what is the benefit of TdT-altered TCRs? @MandlLab show that low-affinity #Tcells generated by TdT are important for curtailing chronic pathogen replication #PLOSBiology https://plos.io/3HJKOCl
@trendless@zeroes.caThe after-effects associated with long COVID could result from the death of T4 lymphocytes during the acute phase
> study of 29 people treated for COVID-19 at the University Hospital of Nîmes, France. In the months following hospitalization, nineteen patients suffered from long COVID, while the other ten had no after-effects.
> the percentage of T4 lymphocytes engaged in a form of programmed cell death (apoptosis) was 37% in the long COVID group and 24% in the other group. By way of comparison, in healthy subjects, the percentage of T4 lymphocytes undergoing apoptosis is approximately 20%; this percentage is comparable to that of patients who have recovered well from their infection, but it is almost half that of patients who have had after-effects.
@persagen@mastodon.socialFountain of youth is a T cell?
https://www.sciencedaily.com/releases/2024/01/240124132847.htm
*reprogramming T cells to fight aging
* eliminate senescent cells in mice: healthier lives; didn't develop aging-associated conditions like obesity and diabetes
* one dose provided young mice with lifelong benefits & rejuvenated older mice
Prophylactic & long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Nature Aging, 2024. http://dx.doi.org/10.1038/s43587-023-00560-5
Scientists have found a way to reprogram T cells to…
www.sciencedaily.comHis second #ERCPoC grant, his third @ERC_Research grant in total: Congrats to our #cancer researcher
Gaetano Gargiulo!
His lab is developing a screening tool to evaluate and enhance lab-produced CAR #Tcells against cancer.
More details: https://www.mdc-berlin.de/news/press/third-erc-grant-gaetano-gargiulo
