#Vesicles
These are public posts tagged with #Vesicles. You can interact with them if you have an account anywhere in the fediverse.
Gas #vesicles are hollow structures made of #protein found in the cells of certain #microorganisms, and researchers at Rice University believe they can be programmed for use in #biomedical applications.
#Microbiology #Biotechnology #Bioengineering #sflorg
https://www.sflorg.com/2024/03/mcb03292401.html
Finding could enable new synthetic biology applications
www.sflorg.comA coordinated recruitment of actin and myosin at large vesicles allows for the "exocytosis by vesicle crumpling" in Drosophila larval salivary glands.
Inès Jmel Boyer covers a preprint from Kumari Kamalesh & team which describes a mechanism that requires precise spatiotemporal control of actomyosin contractility.
#preLight 
https://prelights.biologists.com/highlights/structured-rhogef-recruitment-drives-myosin-ii-organization-on-large-exocytotic-vesicles-v2/
#CellBiology #CellMembrane #biomechanics #exocytosis #vesicles #actin #myosin
The researchers discovered that liver #cells have a clever way of compensating for the missing #enzyme. By clustering together and exchanging tiny, protein-wrapped packages called #vesicles, #liver cells are able to communicate and share the #biochemical materials needed to multiply, allowing them to proliferate even without #Shp2.
#Biology #Medical #sflorg
https://www.sflorg.com/2023/10/bio10172301.html
When times are tough, liver cells come together and…
www.sflorg.comHow do #botulinum toxins get to nerve ends to mediate #neurointoxication?
F. Meunier Lab shows that BoNT/A uptake into #synaptic #vesicles is via hijacking of a tripartite membrane nanocluster of #polysialogangliosides, #synaptotagmin and glycoprotein SV2
https://www.embopress.org/doi/10.15252/embj.2022112095
@pwilmart This method for plasma fractionation is one of those that makes me say to myself ... why didn't I think of that!
Rather than remove all the stuff from the house to find the car keys, they spin down the house and look at the bottom of the tube for them, and there they are.
https://doi.org/10.1002/pmic.202200039
#plasma #proteomics #teammassspec #centrifugation #EV #vesicles #EVOSep #SPE
@neely also works on blood proteomics I think.
@dmacphee@mas.toCellular communication through extracellular vesicles and lipid droplets
#Vesicles #ExtracellularVesicles #lipids #CellBio #Science
Extracellular #vesicles from #Zika #virus-infected cells display viral E protein that binds #ZIKV-neutralizing #antibodies to prevent infection enhancement
https://www.embopress.org/doi/10.15252/embj.2022112096
Inspired by the bubbles #bacteria create inside their #cells; researchers developed a similar system by coating tiny gas #vesicles with #protein. The resulting bubbles are safe, highly stable, and function as contrast agent in medical applications.
#Medical #Physics #sflorg
https://www.sflorg.com/2023/01/med01202301.html
Bacteria produce gas vesicles
www.sflorg.comA Universal Strategy to Promote Secretion of G+/G– Bacterial Extracellular #Vesicles and Its Application in Host Innate #Immune Responses
#Osteoblasts are cells that are responsible for the formation of #bone. They do this by modulating the composition of the #BoneMatrix, which is the material that makes up the bone. Osteoblasts deposit minerals, such as #calcium phosphate hydroxyapatite, in the matrix. This process is thought to be mediated by the release of matrix #vesicles, which are small fragments of the cell membrane.
I came across this #microscopy paper. https://www.nature.com/articles/s41587-022-01519-4
"By blue-shifting the #STED beam and separating #fluorophores by on/off switching, individual fluorophores bound to a #DNA strand are localized with σ = 4.7 Å, corresponding to a fraction of the fluorophore size, with only 2,000 detected #photons ."
This image showing resolution below the size of the fluorophore leaves me speechless.
The paper features images of #DNAorigami, #NuclearPores, synaptic #Vesicles, #ECM (#laminin) and #vilmentin
