These are public posts tagged with #cytoskeletal. You can interact with them if you have an account anywhere in the fediverse.
"Mechanics of Single Cytoskeletal Filaments"
https://doi.org/doi:10.1146/annurev-biophys-030722-120914
https://pubmed.ncbi.nlm.nih.gov/39929532/
#Cytoskeletal #Cytoskeleton #Mechanical #Mechanics
"Density-dependent flow generation in active cytoskeletal fluids"
https://doi.org/doi:10.1038/s41598-024-82864-z
https://pubmed.ncbi.nlm.nih.gov/39732914/
#Cytoskeletal #Actomyosin #Dynamics
"Localized spatiotemporal dynamics in active fluids"
https://doi.org/doi:10.1103/PhysRevE.110.054409
https://pubmed.ncbi.nlm.nih.gov/39690636/
#Cytoskeletal #Mechanics #Dynamics
"We show that migrating #neurons in mice possess a growth cone at the tip of their leading process, similar to that of #axons, in terms of the #cytoskeletal dynamics and functional responsivity through protein tyrosine #phosphatase receptor type sigma (PTPσ). Migrating-neuron growth cones respond to chondroitin sulfate (CS) through PTPσ and collapse, which leads to inhibition of #neuronal migration."
#SoftMatter have just published the [results](https://doi.org/10.1039/D2SM01188C) of a project that Renato Assante, Davide Marenduzzo, Alexander Morozov, and I recently worked on together! What did we do and what's new? Briefly...
The #hydrodynamic behaviour of inhomogeneous #activeNematic gels (such as extensile bundles of #cytoskeletal filaments or suspensions of low #ReynoldsNumber swimmers) can be described by the time evolution of three coupled #PDEs.
Standard #ActiveGel #theory concludes, from a #LinearStabilityAnalysis of these equations, that fluctuations in concentration don't significantly affect emergent #phaseBehaviour. However, this leaves #experimental #observations of visible inhomogeneities in #microtubule–#kinesin mixtures unexplained. As we move away from the passive (quiescent) regime, past the onset of #SpontaneousFlow, and deeper into the active phase, #nonlinearities become more important. What role do concentration inhomogeneities play here?
Alongside #analytic techniques, we used an in-house #MPI-parallel code developed within the #Dedalus #spectral framework to investigate. We predict a #novel regime of #spontaneous #microphaseSeparation into active (nematically ordered) and passive domains. In this regime, active flow arrests macrophase separation, which is itself driven by the thermodynamic coupling between active matter concentration and #nematic order. As a result, domains do not #coarsen past a typical size, which decreases with increasing activity. This regime is one part of the #PhaseDiagram we mapped out.
Along with our other findings, you can read all about it [here](https://doi.org/10.1039/D2SM01188C)!
#CahnHilliard #ActiveMatter #NavierStokes #BerisEdwards #CondensedMatter #PhaseTransitions #TheoreticalPhysics #BioPhysics #StatisticalPhysics #FluidDynamics #ComputationalPhysics #Simulation #FieldTheory #paperthread #NewPaper #science #research
"Multiple conserved states characterize the twist landscape of the bacterial actin homolog MreB"
by Benjamin D Knapp, Michael D Ward, Gregory R Bowman, Handuo Shi, Kerwyn Casey Huang
https://pubmed.ncbi.nlm.nih.gov/36382191/ #Cytoskeletal #Mechanics #Actin
Filament formation by cytoskeletal proteins is critical…
pubmed.ncbi.nlm.nih.gov "Crystal Structure of Schizosaccharomyces pombe Rho1 Reveals Its Evolutionary Relationship with Other Rho GTPases"
by Qingqing Huang, Jiarong Xie, Jayaraman Seetharaman
https://pubmed.ncbi.nlm.nih.gov/36358328/ #Morphogenesis #Cytoskeletal
The Rho protein, a homolog of Ras, is a member of the…
pubmed.ncbi.nlm.nih.gov