Auscandoc

“a #nanoparticle #vaccine that includes a fragment of a #SARSCoV2 protein, and delivered it as an aerosol into the #lungs of mice, hamsters and monkeys. This triggered a strong #mucosal immune response — and stymied the spread of SARS-CoV-2 in vaccinated hamsters housed in cages next to one another” toot.yosh.is/@yosh/11160920937

yosh is holiday posting (@yosh@toot.yosh.is)

Holyyyyyyy, it seems sterilizing vaccines might actually…

toot.yosh.is
Keith Dawson

A preclinical trial in mice demonstrated that an adjuvant in an intranasal vaccine improved mucosal antibody and T cell responses against SARS-CoV-2. The adjuvant both boosted the mucosal immune response and disabled the virus directly. Early days. Remember: mice lie, monkeys exaggerate, and ferrets are not people.

U of M summary / interview
michiganmedicine.org/health-la

Paper
pubmed.ncbi.nlm.nih.gov/373860

#Covid #vaccine #nasal #mucosal

Is there promise of a nasal COVID vaccine for the future?

The vaccine could stop the spread of SARS-CoV-2 at…

www.michiganmedicine.org
daniel

Promises and challenges of #mucosal #COVID19 vaccines

"Several mucosal vaccines are currently being developed with the aim of inducing long-lasting protective immune responses at the mucosal sites where #SARSCoV2 infection begins"

sciencedirect.com/science/arti

Lorraine

Supposing I were a #sociopath #psychopath #Pfizer #CEO
In order to max profits I’d want every woman, man & child #addicted to my #products

It probably wouldn’t be in my best interest to develop an ACTUAL #vaccine that created #mucosal immunity b/c that would mean I’d sell less #diabetes #hbp #antiDepressants #pills ☹️
no, no, no;we can’t have that!

Cosmetics is INCREDIBLY jaw-droppingly #lucrative b/c of something called #replenishment
Imagine 300 million people addicted to constant #Rx🤑

🖕🏼that

Lorraine

@Covidcanada @kudra
🙏🏼🙏🏼🙏🏼🙏🏼🙏🏼
I’m the worst explainer; literally the worst even in regards to my own industry. Your explanation💯

Tend to believe or know things based on personal experience, which is quite unhelpful tbh

Had to “illegally” get #IWantMyNovavax & even convinced my💯ALWAYS-by-the-book-rule&law-abiding SO post my 2 shots,to get #Novavax too

If studies came out proving some
#mucosal protection, I’d believe it as something happens to my nose every time I’m exposed
Annual💉YES!

MBarral

Very nice Clinical Pipeline by @cyrilpedia#IntranasalVaccines COVID-19 #vaccine fails to induce #mucosal-immunity” at #Nature-Med doi: doi.org/10.1038/d41591-022-001

Jen Gommerman

#introduction I am an #immunologist at the #universityoftoronto. I study how our #mucosal immune system can influence our health, especially brain health. I love constructive discussions about science and how to make #academia a better place for everyone. I love #cooking, #gardening, #singing, #canoeing and learning from my 2 sons. Oh and my 3 @Cats too.