#synapses
These are public posts tagged with #synapses. You can interact with them if you have an account anywhere in the fediverse.
https://www.europesays.com/uk/33029/ Synapses Use Multiple Learning Rules to Encode New Information #BrainPlasticity #BrainResearch #learning #neurobiology #neuroplasticity #Neuroscience #Science #synapses #SynapticPlasticity #UCSD #UK #UnitedKingdom
How do diverse synapses in the brain organize their nanoarchitecture? This study uses #nanobodies & STED imaging to study the nanoarchitecture of thalamocortical & corticocortical #synapses, revealing distinct principles of synaptic nano-organization in the brain @PLOSBiology https://plos.io/3FY4vcd
WRITER FUEL: Human brains take in sensory data at more than 1 billion bits per second, but only process that information at a measly 10 bits per second, new research has found.
#LimFic #LiminalFiction #WriterFuel #Writers #Authors #WritersofMastodon #StoryIdeas #HumanBrain #Synapses #Processing
Role of axo-axonic synapses among olfactory receptor neurons (ORNs) in odor decorrelation, mediated by metabotropic acetylcholine receptors:
"Nonlinear high-activity neuronal excitation enhances odor discrimination", Julia E. Manoim-Wolkovitz et al. 2025
https://www.cell.com/current-biology/fulltext/S0960-9822(25)00198-8
#neuroscience #Drosophila #AxoAxonicSynapses #synapses #olfaction
#Cellular structure without a #membrane: Researcher discusses how #synapses use #liquids to create functional separations.
#LLPS #membrane-less_organelles #neurotransmission
https://phys.org/news/2025-03-cellular-membrane-discusses-synapses-liquids.html
The laboratory of Ege Kavalali, professor and chair…
Phys.org"The first synapse was visualized using electron microscopy in the mid–1950s, although parallel work and delicate egos make it difficult to determine with certainty the first researcher to actually see one." – Alexandra Balwit https://www.asimov.press/p/barcoding-brains
Neuroscientists are human after all.
Synapses in the fly brain learning and memory centre, the mushroom body:
"Quantitative characterization of the pattern of Brp clusters across multiple individuals revealed cell-type-dependent synapse heterogeneity and stereotypy. Furthermore, we discovered previously unidentified sub-compartmental synapse configuration and its regulation by cAMP signaling."
From:
"High-throughput synapse profiling reveals cell-type-specific spatial configurations in the fly brain", by Wu et al. (Tanimoto lab) 2025
https://www.biorxiv.org/content/10.1101/2024.12.02.626511v4
Characterization of intracellular synapse heterogeneity…
bioRxivDigital painting: Ambiguous impulses for your mental cinema!
#contemporaryArt #mentalCinema #digitalPainting #climateActionNow #systemChange #endFossilFuels #makeArtNotWar #noAFD #NoRacism #NoFascism #humanrights #humanDignity #Нетвойны #appliedSciences #biology #anatomy #architecture #brain #neocortex #neurosciences #neurobiology #cognition #perception #emotion #innerOrgans #crossSection #synapses #connections #bridge #astronautics #astronauts #spaceSuit #spaceTravel #drawing #oldHand
Why do we learn in our #sleep?
A team from #CharitéBerlin finally has a possible explanation: The slow brain waves typical of deep sleep strengthen the connections between human nerve cells, making the #brain especially receptive to information. The details:
https://www.charite.de/en/service/press_reports/artikel/detail/why_deep_sleep_is_helpful_for_memory/
#medicine #research #science #ScienceMastodon #MedMastodon #CharitéNeuro #CharitéPaper #neuroscience #synapses #SlowWaves
Does neuronal information storage involve nanoscopic structural changes at #synapses? @olenas_kim &co use nanophysiology & functional EM to reveal structural changes of #hippocampal #ActiveZones during chemical potentiation @ISTAustria #PLOSBiology https://plos.io/3V22v7h
Protein translocation at active #synapses. @jaimedejuan & @carlitosroca7 present a method for quantifying translocation of endogenous neuronal proteins to the synaptic surface, visualizing translocation of proteins when #neurons are firing #PLOSBiology https://plos.io/3UsNtqK
Pictures of AMPA receptors at synapses from Axel Brunger's lab. By averaging a lot of tomogram images, they could discern scaffolding molecules bound to the complexes.
These in situ images are lower resolution than purified protein, but retain the native organization and place the receptors somewhat at the side of vesicular docking sites.
https://www.biorxiv.org/content/10.1101/2024.10.19.619226v2
#synapses #neuroscience #CellularStructuralBiology #Receptors
@jimdonegan@mastodon.scot#JosephLeDoux - What is the Nature of the #Self?
https://www.youtube.com/watch?v=NQ0DB0Qn7WQ
#Philosophy #PhilosophyOfMind #Mind #PhilosophyOfConsciousness #Consciousness #Neuron #Neurons #Synapse #Synapses #Psychology #Freud #Person #Personality #Personhood #Identity #PersonalIdentity #CloserToTruth #RobertKuhn
Enjoy the videos and music you love, upload original…
www.youtube.comTurns out the postsynaptic densities (PSD) that we use in electron microscopy to identify synapses aren’t made of large protein aggregates but rather of specialised cellular organelles:
“we combined mouse genetics and cryo-electron tomography to determine the 3D molecular architecture of fresh isolated and anatomically intact synapses in the adult forebrain. The native glutamatergic synapse did not consistently show a high density of proteins at the postsynaptic membrane thought to be characteristic of the PSD. Instead, a ‘synaptoplasm’ consisting of cytoskeletal elements, macromolecular complexes and membrane-bound organelles extended throughout the pre- and post-synaptic compartments.”
Excellent work by Julia Peukes et al. 2024 https://elifesciences.org/reviewed-preprints/100335
"Homeostatic synaptic normalization optimizes learning in network models of neural population codes", Mayzel and Schneidman, 2024.
https://elifesciences.org/reviewed-preprints/96566
From the assessment:
"... an important contribution to the development of a biologically plausible theory of statistical modeling of spiking activity. The authors convincingly implemented the statistical inference of input likelihood in a simple neural circuit, demonstrating the relationship between synaptic homeostasis, neural representations, and computational accuracy."
@jimdonegan@mastodon.scot#PeterTse - How #FreeWill Probes #Mind and #Consciousness
https://www.youtube.com/watch?v=rj5Z-vJP5fc
#Philosophy #PhilosophyOfFreeWill #PhilosophyOfConsciousness #PhilosophyOfMind #PhilosophyOfScience #Science #Information #Neuroscience #Neuron #Neurons #Synapse #Synapses #NeuralCode #Determinism #Physics #Biology #CloserToTruth #RobertKuhn
"Long-term microglia depletion using colony-stimulating-factor-1 receptor (CSF1-R) inhibitor PLX5622 resulted in increased overall spine density, especially of mushroom spines, and increased excitatory postsynaptic current amplitudes."
Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain
Wickel et al., Glia 2024
https://doi.org/10.1002/glia.24541
"The central-pattern-generating network consists of motoneurons interconnected by electrical synapses that, in contrast to doctrine, produce network activity splayed out in time instead of synchronized across neurons. Experimental and mathematical evidence support a generic mechanism for #network desynchronization that relies on weak electrical #synapses and specific excitability #dynamics of the coupled #neurons."