#toxicology

What’s Happening in France in Diet Drug Mediator Scandal? https://www.diningandcooking.com/1992421/whats-happening-in-france-in-diet-drug-mediator-scandal/ #CardiometabolicRisk #crime #criminal #DiabetesMellitusType2 #DiabetesMellitusTypeIi #diet #ethics #francais #france #fraud #fraudulent #French #FrenchDiet #Grant #hands #heart #HeartFailure #Hospitals #hypertension #injury #Insurance(malpractice) #LipidManagement #lipids #malpractice #MalpracticeInsurance #PulmonaryHypertension #scandal #scandalous #toxicology #Type2Diabetes #ValvularHeartDisease #WoundManagement

found two @magnusmanske's Mix'n'Match catalogs important to #VHP4Safety

- CoSing ingredients: https://mix-n-match.toolforge.org/#/catalog/707
- ECHA InfoCard: https://mix-n-match.toolforge.org/#/catalog/1521

#openscience #chemistry #toxicology

Pet Flea Treatments Are Poisoning Wild Birds: Study out of University of Sussex, published by Science of the Total Environment

by @grrlscientist

#ornithology #birds #Pets #FleaTreatments #Ecology #toxicology #pesticides #SciComm https://www.forbes.com/sites/grrlscientist/2025/03/10/pet-flea-treatments-are-poisoning-wild-birds-study/

Pet Flea Treatments Are Poisoning Wild Birds: Study out of University of Sussex, published by Science of the Total Environment

by @grrlscientist

#ornithology #birds #Pets #FleaTreatments #Ecology #toxicology #pesticides #SciComm https://www.forbes.com/sites/grrlscientist/2025/03/10/pet-flea-treatments-are-poisoning-wild-birds-study/

Pet Flea Treatments Are Poisoning Wild Birds: Study out of University of Sussex, published by Science of the Total Environment

by @GrrlScientist

#ornithology #birds #Pets #FleaTreatments #Ecology #toxicology #pesticides #SciComm https://www.forbes.com/sites/grrlscientist/2025/03/10/pet-flea-treatments-are-poisoning-wild-birds-study/

If you do evidence synthesis in #toxicology or #EnvironmentalHealth, time to start paying attention to the #NoIRISAct, which would prevent EPA from using the chemical assessments in IRIS in regulatory actions.

Read this: https://www.propublica.org/article/legislation-targets-epa-science-toxic-chemicals

@Umweltbundesamt

PFAS are one of the most important pollution issues of our times.

Thank you for giving attention to the topic!

#PFAS #Ecotoxicology #Toxicology #Pollution

Targeting the root of NLRP3 inflammation

This #preprint from Rebecca Coll & team “highlights the complexity of immune signaling and the importance of considering many variables (...) when developing (…) therapeutic compounds”

Excellent #preLight prepared by Roberto Amadio

https://prelights.biologists.com/highlights/discovery-of-a-potent-and-selective-inhibitor-of-human-nlrp3-with-a-novel-binding-modality-and-mechanism-of-action/

#biology #biochemistry #immunology #pharmacology #toxicology #therapeutics

Human brain may contain up to seven grams of #microplastics and #nanoplastics

https://www.smithsonianmag.com/smart-news/the-human-brain-may-contain-as-much-as-a-spoons-worth-of-microplastics-new-research-suggests-180985995/

#neuroscience #toxicology #ClimateCrisis

@corporateeurope

Industrial pollutants like PFAS are an example of the impressive dysfunctionality of the chemical industry and "our" administrations' unwillingness to restrict this sector with a horrible impact on environmental and human health but comparatively low added benefits for society as a whole.

#PFAS #Toxicology #CorporateEurope #Pollution

The smoking gun: Plastic is harmful for your neurons

Manuel Lessi highlights a #preprint describing molecular mechanisms altered by polystyrene nanoplastics in neuronal cells.

#preLight includes a thoughtful discussion with first author Winanto

https://prelights.biologists.com/highlights/polystyrene-nanoplastics-promote-neurodegeneration-by-catalyzing-tdp43-hyperphosphorylation/

#biology #neuroscience #pharmacology #toxicology #iPSCs #nanoplastic #neurodegeneration

/1
* 75+ trade groups against EPA findings
* Trump2 EPA appointee David Dunlap: https://en.wikipedia.org/wiki/David_Dunlap_(lobbyist)
* dir. environmental regulatory affairs, Koch Industries
* tried to persuade EPA formaldehyde doesn’t cause leukemia
* Koch subsidiary Georgia-Pacific made formaldehyde, products that emit it (since sold chem biz to Bakelite Synthetics)
* at EPA Dunlap had authority over division working on toxicity report

#toxicology #formaldehyde #OHS #EnvironmentalHealth #pollutants #cancer #KochIndustries

Formaldehyde Causes More Cancer Than Any Other Air Pollutant. Little Done to Curb the Risk
https://www.propublica.org/article/formaldehyde-epa-trump-public-health-danger

* WHO: formaldehyde = carcinogen
* EPA: 320M Americans live in areas where lifetime cancer risk from outdoor exposure to formaldehyde 10x higher EPA limit
* Trump vowed to roll back regs he views as anti-business
* typical home has formaldehyde level >3x higher than EPA limit
...

#toxicology #formaldehyde #OHS #EnvironmentalHealth #pollutants #cancer #CharlesKoch #KochIndustries

One of the sad consequences of the state of US affairs under #45 is that you can't trust reports on scientific issues any longer. Because information that doesn't suit the billionaire oligarchy, will be erased.

#toxicology #epa #chemicals #safety

https://www.propublica.org/article/epa-scientists-faced-retaliation-after-finding-harm-from-chemicals?utm_source=mastodon&utm_medium=social&utm_campaign=mastodon-post

@ClimateNewsNow

Become a toxicologist, you will never run out of work...

Especially in a capitalist world where new chemicals are developed by the week and released into the environment, creating degradation products and complex mixtures...

We need definitely more large-scale/long-term toxicology studies to understand the effects of these cocktails.

#Toxicology #PublicHealth

there are some places left for the second @elixir_europe Toxicology Community INTOXICOM workshop in #Basel in ~two weeks, with the preparatory webinar tomorrow.

Topics: #toxicology, #chemistry, #FAIR, FAIR Cookbook, training material (TeSS), DS-Wizard templates, and exchanging metadata with/from ELIXIR and toxicology projects.

https://www.aanmelder.nl/intoxicom-ws-2/wiki/1141161/wp-2-features-ws-2

#OnThisDay Gottfried Leibniz demonstrated integral #Calculus for the first time (1675).

Birth Anniversary of Swiss physician Paracelsus (1493) - pioneer in several aspects of the "medical revolution" of the Renaissance. He is credited as the "father of #Toxicology".

Happy Birthday #Actor Leonardo DiCaprio (1974).

https://knowledgezone.co.in/news

new report/preprint from the @elixir_europe Toxicology Community: "INTOXICOM Workshop Report: FAIRification of Toxicological Research Output: Leveraging ELIXIR Resources" https://doi.org/10.37044/osf.io/un2rw

#toxicology

the @elixir_europe Toxicology Community organizes its second INTOXICOM workshop next month: https://www.aanmelder.nl/intoxicom-ws-2/wiki/1141161/wp-2-features-ws-2

The overall topic will be research output management, and we focus on more than FAIR data, but also on training material, FAIR Cookbook recipes, wizards, and actual reuse of metadata to support toxicological research

#fair #toxicology #safety

Fwd: "Advancing AI in #toxicology Insights from the Third #VHP4Safety Hackathon" https://www.sciencrew.com/c/9347/a/335221636?title=Advancing_AI_in_Toxicology_Insights_from_the_Third_VHP4Safety_H