Since I've taken up this platform I've only put out one post "of my own" and that was really just a test to see if anyone would engage on this strange, new place I was checking out. I prefer to respond to other people and discuss what's on their minds rather than to put my own topics out there. But this has really been bugging me lately, so I'm going to throw it out there and if no one cares then nothing changes and I'll keep kicking it around in my own mind.

If you don't want to hear or think about COVID feel free to tune out now and not follow along with the rest of my thoughts.

I am really interested in what people have to say here, and I welcome any real life thoughts on the subject whether you are having the same experiences or not. What I'm really not interested in is any "COVID isn't real" or "plandemic" nonsense and I'll block accordingly.

I'm a scientist. I think accordingly I like numbers and stats. Those stats are often hard to come by during things like a pandemic, because science is often slow.

So, while I read a lot of studies and journals about what's going on in the world, one of the first things I did as I realized what *could* be happening was to start reading personal accounts wherever I could. One of the places that I keep in my mind daily is the long haulers sub on reddit. Every day I remind myself about the human toll by reading their, often jarringly, personal takes.

In that vain, I've been thinking a lot lately about the people I know and care for. My wife and I have never kept a very large social circle. It's just not the type of people we are. But, we have some family nearby and a handful of friends and coworkers with whom we keep in touch.

I'd like to share some generic info about the people we are closest to and what I'm really curious about is:

Is our experience unusual? Are you seeing something similar?

All anecdotal, of course. I'm not looking for a scientific, case study on the people around you. Just, generally, is this the way the world is now?

First up, my father. He's in his 70's, so some decline isn't unexpected. However, he's always been a very active person with a sharp mind. In his own words, since his 2nd COVID infection recently, he's "not up to much of anything" physically, and has absolutely crushing brain fog. I don't know if I've ever known someone who's read as many books as he has, but, he just can't at this point.

Continuing with family, my wife's parents. My mother in-law was never the healthiest person. It's hard to tease out her longterm issues from her more recent, but, cognitively she never had issues until recently. Now she's basically exactly what you see in the movies when they're trying to show you that someone's begging the decent into dementia. My father in-law had zero health issues until this year and now has cancer. COVID related from T-cell issues or not at all related there's no way to tell.

My wife's best friend since they were kids is clearly the lucky one here. She locked herself down for two years, never went anywhere without a mask and then at the beginning of this year just decided to be done with all of that. She's travelled around the country to weddings and restaurants and swears she's as healthy as ever and never even got sick this year. I take her at her word.

My best friend, on the other hand, also was extremely cautious for a couple of years and then decided he was over it early this year. He's a veteran and hasn't missed his morning run, rain, sleet or snow, for decades....until he got COVID. Afterward he physically couldn't any longer. All of his joints hurt. He was diagnosed with autoimmune, or rheumatoid, arthritis. Now, if you ask him COVID has absolutely nothing to do with it. It was just a coincidence, and, again, I'm not here to argue that. I'm talking strictly anecdotal experiences here.

Another friend of mine is a really smart scientific mind. He's a science teacher and decided early on that he was going to go through whatever happened while in the classroom. I don't know exactly how many COVID infections he's had, let's just call it multiple. Neither him, his wife, nor their two kids can get healthy at this point. He's missed over 50% of his work days this semester, his kids are never able to go to daycare or school, and it's just one infection after another. The flu, croup, RSV, colds, COVID, etc. In his own words he just "can't get healthy. It's like my immune system doesn't work anymore" but he, also, believes it has nothing to do with COVID. Not that he has an explanation, but, clearly not COVID in his mind.

My wife's friend, also a teacher, has had an almost identical experience. Without belaboring the point, she is sick all of the time. Sadly, her little kid, now 2, has spent half of her life constantly sick. Just last week she was telling my wife that all she wanted was for them to be healthy for 2 weeks. Just 2 weeks and maybe they could have a good Christmas. They haven't managed 2 weeks once this semester. So what happened? This morning she was practically sobbing to my wife that they're sick, again, and she's far too sick to make it in to teach today.

One more case in my little anecdotal study here, for now. My wife's boss. She, thankfully, seems to see the problems. Recently she allowed my wife to skip a "mandatory" in person meeting(we both work from home, and I have worked from home since ~2015 when I stepped out of the lab) when my wife said she was still being COVID cautious. Her response was that she wished she had been because she was recovering from her 5th infection and after her 4th she developed "a mysterious autoimmune disorder" that her doctor was having a hard time figuring out. She realizes that it was likely COVID, but, still takes very few precautions.

I'll leave it at that for now. I just needed to put this down somewhere, probably to help me wrap my own head around it. I'm surrounded by what I think that I clearly see as cognitive dissonance. In the midst of a global pandemic how can you be constantly sick, but think the two are unrelated? How can you think that they might be related, but still do nothing about it?

And, again, I really wonder....is it just me? Do I know a lot of people who seem adversely affected, and have gone from extremely healthy to very unhealthy over the last year or two while other people don't? Or is this what everyone is seeing, but, somehow not reacting to?

Lately I kick all of this around in my head wondering what the end game is, but, perhaps I'm asking the wrong questions because I read a lot of scientific studies and apply what I'm reading to the world around me, and in the end my experiences aren't what everyone else is seeing?

@BE My spouse and I have been very cautious. We don't have kids, we don't have people over, we don't seek out social gatherings. At work, in stores, at medical offices, we at least wear surgical masks. He's had to travel some recently and wore a KN95 the whole time. Neither of us have ever tested positive.

Our parents are all in their 70s and 80s. His parents (older) are basically hermits and haven't had it. My parents are low-to-medium social and have each had it once, incredibly mild (like 6 hrs of symptoms and then done). They wear cloth masks indoors in public, made according to the best materials and construction I could come up with based on the literature at the time. They visit their out-of-state grandkids around once a month except during the winter. So far, they don't seem any the worse for wear. No new conditions, no cognitive impairments that I can discern.

My sib and sib-in-law are both university professors and have one kid in primary school and another one in pre-K. The little one tested positive once, but nobody else in the house did. This was another case of a day or less of symptoms followed by a quick return to evident health. Since 2019ish, the kids have each had one pretty severe bout of influenza, and they both had RSV earlier this season. They try to keep everybody in masks when they're in a crowded public place, but that's hard with the littles and so few other people reinforcing the behavior. They are also not ragingly social, but they have the added risk of swim lessons and dance lessons and track meets and such.

Spouse's sib & family are extremely isolated - they live in a rural area, the kids (tweens) are homeschooled, sib doesn't work (but has an MD), and the spouse is WFH about 50% of the time. They recently had covid go through the house and are still recovering.

All of the adults in this cohort are chemists, engineers of varying stripes, or medical doctors. We all take this very seriously, and nobody is under the illusion that the pandemic is "over." Some people's precautions have loosened a little (see also: children), but nobody has gone completely pre-pandemic.

I feel like we've been exceedingly lucky. We're all *aware* that we've been exceedingly lucky, and we're not inclined to tempt fate. Most of the people I know who had it once have re-upped their mask game and avoided repeat infection. I think we're all grateful to mostly be raging introverts who don't go out very much.

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These are the kinds of personal stories that are hard to come by out there. I really appreciate you taking the time to respond and I hope you all continue to stay healthy!

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