From micro to macro: a trip from the assembly of #collagen to the formation of bone tissue. This image represents the work of Giulia Giubertoni and colleagues at the University of Amsterdam, revealing the crucial role of water in determining the mechanical properties of collagen. Exciting findings which can significantly improve our understanding of the molecular roots of tissue dysfunction diseases, such as #OsteogenesisImperfecta.
For a deeper look check out:
➡ Paper: https://www.pnas.org/doi/10.1073/pnas.2313162121
➡ Press release: https://hims.uva.nl/content/news/2024/03/how-water-guides-the-assembly-of-collagen-the-building-block-of-all-humans.html?origin=QHAZwjzdTzivRzgW9Q2Rng