Since I've taken up this platform I've only put out one post "of my own" and that was really just a test to see if anyone would engage on this strange, new place I was checking out. I prefer to respond to other people and discuss what's on their minds rather than to put my own topics out there. But this has really been bugging me lately, so I'm going to throw it out there and if no one cares then nothing changes and I'll keep kicking it around in my own mind.

If you don't want to hear or think about COVID feel free to tune out now and not follow along with the rest of my thoughts.

I am really interested in what people have to say here, and I welcome any real life thoughts on the subject whether you are having the same experiences or not. What I'm really not interested in is any "COVID isn't real" or "plandemic" nonsense and I'll block accordingly.

I'm a scientist. I think accordingly I like numbers and stats. Those stats are often hard to come by during things like a pandemic, because science is often slow.

So, while I read a lot of studies and journals about what's going on in the world, one of the first things I did as I realized what *could* be happening was to start reading personal accounts wherever I could. One of the places that I keep in my mind daily is the long haulers sub on reddit. Every day I remind myself about the human toll by reading their, often jarringly, personal takes.

In that vain, I've been thinking a lot lately about the people I know and care for. My wife and I have never kept a very large social circle. It's just not the type of people we are. But, we have some family nearby and a handful of friends and coworkers with whom we keep in touch.

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I'd like to share some generic info about the people we are closest to and what I'm really curious about is:

Is our experience unusual? Are you seeing something similar?

All anecdotal, of course. I'm not looking for a scientific, case study on the people around you. Just, generally, is this the way the world is now?

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First up, my father. He's in his 70's, so some decline isn't unexpected. However, he's always been a very active person with a sharp mind. In his own words, since his 2nd COVID infection recently, he's "not up to much of anything" physically, and has absolutely crushing brain fog. I don't know if I've ever known someone who's read as many books as he has, but, he just can't at this point.

Continuing with family, my wife's parents. My mother in-law was never the healthiest person. It's hard to tease out her longterm issues from her more recent, but, cognitively she never had issues until recently. Now she's basically exactly what you see in the movies when they're trying to show you that someone's begging the decent into dementia. My father in-law had zero health issues until this year and now has cancer. COVID related from T-cell issues or not at all related there's no way to tell.

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My wife's best friend since they were kids is clearly the lucky one here. She locked herself down for two years, never went anywhere without a mask and then at the beginning of this year just decided to be done with all of that. She's travelled around the country to weddings and restaurants and swears she's as healthy as ever and never even got sick this year. I take her at her word.

My best friend, on the other hand, also was extremely cautious for a couple of years and then decided he was over it early this year. He's a veteran and hasn't missed his morning run, rain, sleet or snow, for decades....until he got COVID. Afterward he physically couldn't any longer. All of his joints hurt. He was diagnosed with autoimmune, or rheumatoid, arthritis. Now, if you ask him COVID has absolutely nothing to do with it. It was just a coincidence, and, again, I'm not here to argue that. I'm talking strictly anecdotal experiences here.

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Another friend of mine is a really smart scientific mind. He's a science teacher and decided early on that he was going to go through whatever happened while in the classroom. I don't know exactly how many COVID infections he's had, let's just call it multiple. Neither him, his wife, nor their two kids can get healthy at this point. He's missed over 50% of his work days this semester, his kids are never able to go to daycare or school, and it's just one infection after another. The flu, croup, RSV, colds, COVID, etc. In his own words he just "can't get healthy. It's like my immune system doesn't work anymore" but he, also, believes it has nothing to do with COVID. Not that he has an explanation, but, clearly not COVID in his mind.

My wife's friend, also a teacher, has had an almost identical experience. Without belaboring the point, she is sick all of the time. Sadly, her little kid, now 2, has spent half of her life constantly sick. Just last week she was telling my wife that all she wanted was for them to be healthy for 2 weeks. Just 2 weeks and maybe they could have a good Christmas. They haven't managed 2 weeks once this semester. So what happened? This morning she was practically sobbing to my wife that they're sick, again, and she's far too sick to make it in to teach today.

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One more case in my little anecdotal study here, for now. My wife's boss. She, thankfully, seems to see the problems. Recently she allowed my wife to skip a "mandatory" in person meeting(we both work from home, and I have worked from home since ~2015 when I stepped out of the lab) when my wife said she was still being COVID cautious. Her response was that she wished she had been because she was recovering from her 5th infection and after her 4th she developed "a mysterious autoimmune disorder" that her doctor was having a hard time figuring out. She realizes that it was likely COVID, but, still takes very few precautions.

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I'll leave it at that for now. I just needed to put this down somewhere, probably to help me wrap my own head around it. I'm surrounded by what I think that I clearly see as cognitive dissonance. In the midst of a global pandemic how can you be constantly sick, but think the two are unrelated? How can you think that they might be related, but still do nothing about it?

And, again, I really wonder....is it just me? Do I know a lot of people who seem adversely affected, and have gone from extremely healthy to very unhealthy over the last year or two while other people don't? Or is this what everyone is seeing, but, somehow not reacting to?

Lately I kick all of this around in my head wondering what the end game is, but, perhaps I'm asking the wrong questions because I read a lot of scientific studies and apply what I'm reading to the world around me, and in the end my experiences aren't what everyone else is seeing?

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@BE I haven't observed anyone in my sphere who is exhibiting any of the issues in your anecdotes, but I know that I will now be hyper-observative. It's super interesting to me; thank you for sharing them.

Sort of off the subject, but do you know if one can test for long covid, especially if one has gotten all the vax? I know there are often micro clots present in LC patients, but would they be present if, say, the person takes blood thinners?

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@Bette

I really appreciate you taking the time to respond!

Questions like this are really important if we're going to move forward, too.

Off the top of my head I remember that the Long COVID Research Initiative was working on a test for micro clots. I don't know if that's out there and available yet, but, while giving it a quick google search I found this from WebMD:

webmd.com/lung/news/20221207/m

Having a legit test for Long COVID would be a real game changer. I know there was a study that showed certain blood markers showed up frequently with long COVID, and I just found a Nature article about it:

nature.com/articles/d41586-022

But, long story short, this is one of those situations that the science needs to catch up with the happenings in the world. A real diagnosis would mean a lot to the people who are struggling.

@BE Thanks for the links! My daughter has had Covid twice, but had no symptoms the first time; she only found out after a chiro recommended an antibody test & she tested positive. The second time (post 1st vaccine) though, she said was horrible. Now after being made aware by your anecdotes, I do recall asking her many times during our phone convos whether she had a cold ... she sounded like she did. She manages a restaurant, so I'm now wondering if LC is contagious like COVID?

@Bette

Having watched the way some people seem to have so many issues post-COVID infection and some just don't I've often wondered if it largely comes down to which variant, or how large of a viral dose they get. It's probably a mix of all of it.

Each variant seems to have distinct paths which it takes. Some are more in the nasal passages and lungs, some more in the throat, etc. I'm sure whether you're briefly exposed versus sitting in a cloud of viral shedding for hours makes a difference as well.

There's so many studies going on and so far that science has to go before it catches up with people's experiences out in the world on this virus. As a scientist I hate to give advice before "all of the science is in" so to speak, but, as an example, my dad asked me just this morning if I knew anything that could help him out with his symptoms. It's probably been about a month since he had COVID and particularly the brain fog is hard for him to deal with. I don't think there's been any sort of conclusive science on the issue, but, I also don't want to leave him hanging, so I suggested a few things I've seen people say helps.

We're in really uncharted(modern) times. Hopefully your daughter comes through them relatively unscathed!

@BE Thanks, me too. I'll see her soon, so I might do a bit of questioning. No, I WILL do a bit of questioning.

So. Many. Variables. And variants. Not to mention existing conditions. Asthma. COPD, ad infinitum. THIS is why I became an English major!😀

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