RT @1goodtern@twitter.com
🚨
Occasionally a new bit of SARS-CoV-2 research just smashes through the door.
This is one of them.
It's jaw dropping.
It's about Covid persisting after the initial infection and the ongoing damage that causes.
👇🔥👇🔥👇
https://onlinelibrary.wiley.com/doi/10.1002/path.6035
🐦🔗: https://twitter.com/1goodtern/status/1616130001115529240
I've been hoping to see more discussion of this paper. I've been thinking about it a lot since I read it yesterday.
Yes, it's a small number of individuals and they skew towards older(youngest was 53, I believe), but the implications are pretty bad if I'm reading it correctly.
At this stage of the game, it strikes me as really weird to characterize a finding like this as having bad implications. The bad implications about Covid were plain from the nakedly obvious epidemiological fact we're up to our noses in corpses and cripples and contagion - this merely proposes a hypothesis and evidence for it as to why the obvious is happening.
It is a logical fault to refuse to believe the existence of a phenomenon for which there is good evidence, just because one doesn't know the mechanism of that phenomenon yet.
The *real* bad implication of this study, like every other study that finds evidence of COVID anywhere besides the superficial membranes of the respiratory system, is just how wedded medical practice and the culture of medicine is to exactly that logical error.
That live, replicating SARS-CoV-2 was hiding somewhere in the body was always the parsimonious explanation of failure to recover from acute COVID.
Who's refusing to believe the existence of corpses cripples and contagion? Not me. Not Dr Leonardi.
I think you're wildly missing the point here. Without a mechanism you can't solve it. Some mechanisms are worse than others.
Live SARS across your body, replicating, was not always the only explanation. In fact, I will still argue that there's multiple causes and this is just one.
It does jibe, though, because as I said "Some mechanisms are worse than others" so therefore you can assume that I believe this one has particularly bad implications for everyone out there getting COVID.
There's lots of doctors on Mastodon doing a much better job discussing the implications of this article now than I could, so I'll leave it there.
@BE @fitterhappierAJ I am glad you understand all those things. They don't quite jibe with what you initially said.