IMAGE Lab @LabPhan@qoto.org

RT @simocristea
Interested in how classical rule-based modular biology & #deeplearning fit together for the design of artificial proteins?

A new preprint combines these two modeling strategies to generate novel proteins!

Let's take a closer look at this innovative framework🧵👇

RT @fabian_theis
Congrats to @morris_lab for CellOracle out @Nature today! Joining recent approaches (Pando, Scenic+, chemCPA) to aim at OOD prediction of perturbation effects, CellOracle builds a putative gene regulation model, and has an impressive set of validations.
http://nature.com/articles/s41586-022-05688-9

RT @sykristinsson
The first study on the prevalence of smoldering myeloma just published in @NatureMedicine !

Full link: https://rdcu.be/c4026

We found the prevalence of SMM to be 0.5% in people >40 years

RT @lisaharveysmith
For those wanting to see the 'green comet' from Australia, wait until Tuesday-Wednesday since tonight there is a bright moon and it is very low in the sky. This is the view at 9pm from Sydney. For more info: https://lisaharveysmith.com/blog%3A-under-the-stars/f/a-comet-is-on-its-way-how-to-see-it #comet #CometZTF #greencomet

RT @Cancer_Research
The custom microscopes in the ACRF INCITe Centre – the ‘EndoNICHEscope’ and ‘Molecular NICHEscope’ – will help researchers to study living tumours and give insight into how drug-resistant cancer cells develop and how they interact within the immune system. https://www.acrf.com.au/news/media-releases/world-first-australian-designed-microscopes/

RT @acapellascience
LEUKOCYTE: a complete musical overview of the human immune system

hope @bts_bighit don't mind :)

RT @simocristea
The science of #immunotherapy can cure a patient's otherwise incurable cancer.

But sometimes immunotherapy fails completely

Shockingly, we hardly know why.

A meta-analysis of #Genomics & #Transcriptomics in >1,000 immunotherapy-treated patients aims to better understand why🧵

RT @AkaashKumarBME
It's been a while since I uploaded live cell multispectral data so here are 7 organelles in 2 live cancer cells! Finally found a colour combination that allows the viewer to distinguish all 7 targets!

RT @will_townes
Nonnegative spatial factorization: a new preprint with @BeEngelhardt https://arxiv.org/abs/2110.06122. NSF is probabilistic, spatially-aware, interpretable dimension reduction for count data. We illustrate with applications to spatial transcriptomics.

RT @GarvanInstitute
For the festive season, we like to reflect on some of our accomplishments throughout the year. This May, our researchers revealed that follow-up genetic testing gives patients a further chance of diagnosis. http://ow.ly/R4QF50M7PEv

RT @ScienceScottT
Doing #SingleCell #RNAseq? Ever wonder if all those clusters are real? Turns out most feature selection & clustering pipelines can't tell when there's only 1 cluster! But I found a solution! 🧵👇

RT @betacellgirl
Loved the Lafferty debate/roast/disco 😂 Brilliant teams on both sides 👏

@sumaira_hasnain @CvandeSandt @DrAshHaque @_fernace @stutangye
@Immetab_asi @Stromal_Immunol @ImmunoGroupVic #teamdiscoveryisnotdead

#ASI2022MEL #TcellsForLife @iMOD_lab @ASImmunology https://twitter.com/i/web/status/1598228449855819777

RT @Ali_Dvorscek
@ramadhenni from @LabPhan beautifully describes the difference between local and recirculating memory B cells based on their molecular processes, migration patterns, cellular dynamics and cell fates @ASImmunology #ASI2022MEL

RT @mscienceaustnz
Goodluck to this year's #ASI2022MEL Lafferty Debate debaters at @ASImmunology.

@K_RenfreeShort @CvandeSandt @_fernace
@shalinhnaik @DrAshHaque @sumaira_hasnain https://twitter.com/mscienceaustnz/status/1597517334553694208

RT @fabian_theis
1/n Single-cell data analysis is complex with many tools to choose from - but which ones work best and should be used when? Led by @LukasHeumos and @AnnaCSchaar, we wrote a free online book that aims to guide single-cell data analysts: https://sc-best-practices.org