How does experience affect representational drift in the visual system? We provide new insights from the brilliant Joel Bauer, Uwe Lewin and @_eherbert as they study V1 through extensive longitudinal recording & modeling—highlighting the impact of experienced oriented contours!:
Tweeprint here:
https://x.com/Neuro_Joel/status/1706203566162038922?s=20
Very happy to be part of a productive team effort of
Joel Bauer, Uwe Lewin, Julijana Gjorgjieva Carl Schoonover, Andrew Fink, Tobias Bonhoeffer and Mark Hübener!
Ever wondered how animals sleep? Sleep experts Niels Rattenborg and Gianina Ungurean have published a great summary about the evolution and diversification of sleep in the animal kingdom. Read the review here: https://authors.elsevier.com/a/1g6OqcZ3WuSvZ
Art by @somedonkey
🚨 BIG DATA RELEASE 🚨 We are beyond excited to announce the release of our Brain Wide Map of neural activity during decision making! It consists of 547 Neuropixel recordings of 32784 neurons across 194 regions of the mouse brain 🐭🧠
All these recordings were performed in a distributed fashion in 12 different labs, spanning Europe and the US 🌎 Rigorous standardization of methods and materials allowed us to pool the data from these labs together into a single gigantic dataset 🐙
Mice are performing our standardized perceptual decision-making task in which they have to position a stimulus in the center of a screen to receive reward. The dataset contains the stimuli and decisions, but also videos from three angles and DeepLabCut pose information. We're even releasing all the raw ephys data!
We know, it's a lot. At your own pace you can read all the details about the experimental setup, the task, processing of the data, and much more in the technical paper which accompanies this data release: https://figshare.com/articles/preprint/Data_release_-_Brainwide_map_-_Q4_2022/21400815
To explore the data at your leisure, visit our visualization website where you can scroll through different recording sessions, look at neural activity during example trials, and see trial-based activity of single neurons: https://viz.internationalbrainlab.org
Do you have itchy fingers to run your models on this humongous dataset? We totally get it! Here you can find how to download the data using our API so you can fire up those computing clusters: https://int-brain-lab.github.io/iblenv/notebooks_external/data_release_brainwidemap.html
This was a collective effort of our stellar team, who all put in so much work to make this monumental achievement possible. Our collaboration consists of 22 PIs, 37 researchers, and 11 staff members who all worked tirelessly to bring these data to you, the community 👏🍾
#Introduction. I'm a theoretical neuroscientist at U Mainz Medical Center and co-affiliated with U Bonn Medical center. Primary focus on cortical circuits, their network activity, synaptic plasticity and protein dynamics in dendrites. Broadly interested how circuits learn e.g. neuro/AI interface and want to understand how neural networks compute, both algorithmically and intracellularly. Occational posts about societal and academic issues.
Neuroscientist at heart, with too many hobbies and PhD student in the Bonhoeffer Lab.
I investigate the stability of visual sensory representations and binocular convergence in the dLGN of mice.