Buxus sempervirens - Wikipedia
https://en.m.wikipedia.org/wiki/Buxus_sempervirens
B. sempervirens wasn’t known for its medical use until the beginning of the 1600s.[22] After this it was found that the leaves (containing alkaloids, oils and tannin), the bark (containing chlorophyll, wax, resin, lignin and minerals) and the oil from the wood had a medical effect.[23] It then was used to treat gout, urinary tract infections, intestinal worms, chronic skin problems, syphilis, hemorrhoids, epilepsy, headache and piles,[24] but also had the reputation of curing leprosy, rheumatism, HIV, fever and malaria.[25][26] For treating malaria it was used as a substitute for quinine, but because of the side effects and the fact that there are better medicinal alternatives than B. sempervirens it is normally not used any more to treat these diseases.[27]