Thijs Bressers @Tbressers@qoto.org

RT @Jayquerido
Excited to share our new preprint (Brito Querido et al).
The structure of a human translation initiation complex reveals a second molecule of the helicase eIF4A at the mRNA entry site, on the opposite side of the 43S from eIF4F. https://www.biorxiv.org/content/10.1101/2022.12.07.519490v1
#CryoEM #science #mRNA

RT @ChemBioChlo
@rRNAte_ & I are excited to share our work where we visualize native assembly intermediates of the small subunit of the mitochondrial ribosome in yeast and human cells https://www.nature.com/articles/s41586-022-05621-0

RT @MPIbp
New insights into mitochondrial complex I by #CryoEM published by our Structural Biology Department in cooperation with our Langer Lab in @ScienceAdvances: The giant enzyme undergoes a transition between two states characterised by a twisting motion and substantial restructuring.

RT @WuLabHarvard
So excited that we finally have the ACTIVE NLRP3 inflammasome structure, thanks to super talented Le Xiao @LeXiao17, and Venkat Magupalli @MagupalliVenny! https://www.nature.com/articles/s41586-022-05570-8

RT @lab_locher
We are very happy to share our latest article "Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase" in @NatureComms. https://www.nature.com/articles/s41467-022-35067-x

RT @DmytroKuleba
90 years ago, Stalin used hunger as a weapon to starve millions of Ukrainians. Light a candle tonight to commemorate victims of the 1932-1933 Holodomor genocide and mass artificial famines of 1921-1922 and 1946-1947. We survived then and we will not give up or break down today.

RT @PiperProteins
#Render of the week is presenting a short molecular dynamics animation on #GPCR peptide binding process, prepared in @Blender using @bradyajohnston MolecularNodes, showing the ligand peptide (in blue) and receptor in black! #MD and #CryoEM data based on our recent paper 👇 (1/2)

RT @TolarLab
Our new structure of the Fcμ receptor binding to IgM is out on @biorxivpreprint.
There are four binding sites for FcμR on each side of the IgM pentamer, explaining isotype specificity and receptor crosslinking.
Again with Peter Rosenthal @TheCrick.
https://www.biorxiv.org/content/10.1101/2022.11.18.517032v1

RT @TerwillTom
Wondering just how accurate #AlphaFold models are? Here is a handy chart!

The median error for high-confidence residues is just 0.6 Å!
Caution: 10% are off by over 2 Å.

#AlphaFold predictions are great #hypotheses

@buildmodels @PDBeurope @DeepMind

https://www.biorxiv.org/content/10.1101/2022.11.21.517405v1

RT @Shayan86
This is an account owned by a man linked to Iran's Revolutionary Guards who, in his own words, beats up and arrests anti-regime protesters on the streets of Tehran. He even tweets clips of protesters he beats up and detains.

Why is he allowed to do this on Twitter? @elonmusk

RT @GatsogiannisLab
📢New preprint: We elucidated the structure of the peroxisomal Pex1/Pex6 ATPase complex processing an endogenous substrate. Kudos @RuetterM and all co-authors. #cryoEM #peroxisome #pexophagy @WWU_Muenster #SoN https://www.biorxiv.org/content/10.1101/2022.11.19.517173v1

RT @VIKorolchuk
Our paper #Autophagy promotes cell survival by maintaining #NAD levels is not published in @Dev_Cell.
Congratulations to all the authors and a big Thanks to the Editors and Reviewers!

https://www.cell.com/developmental-cell/fulltext/S1534-5807(22)00760-2#.Y3udkvrzUCI.twitter

Also on the cover thanks to an amazing design by @HSalmonowicz!

RT @phospho
Incredibly excited to finally share this.. We’ve charted the full life cycle of the SARS-CoV-2 coronavirus with @MaastrichtU. Follow us inside the cell and see exactly what happens during an infection https://youtu.be/k2GlafQ9YhY

RT @WChengLab
Our latest study is now published!

"Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation" https://www.nature.com/articles/s41467-022-34813-5

RT @IBC2_GU
Exciting insights in complex I assembly: A new link with #cardiolipin remodeling is now published in @ScienceAdvances by @IBC2_GU group leader Volker Zickermann & @JanetVonck from @MPIbp. https://www.science.org/doi/10.1126/sciadv.add3855#.Y3YB_1SvwFo.twitter

@CardioPhys_FFM @goetheuni @dfg_public @BMBF_Bund @maxplanckpress

RT @PiperProteins
Behind @PiperProteins is an actual scientist & that scientist publishes actual science in @NatureComms 🥳We use #CryoEM and #MD simulations to look at membrane receptors to better understand how these are activated! Stay tuned for more animations https://www.nature.com/articles/s41467-022-34629-3 (1/2)

RT @ramin_m_h
In a new article published today in Nature MI @NatMachIntell we solved a differential equation that describes the interaction of neurons and synapses! This equation had no known closed-form solution since the year 1907!

This solution is important! 1/n

https://www.csail.mit.edu/news/solving-brain-dynamics-gives-rise-flexible-machine-learning-models

RT @Laura_Spagnolo_
And here's our latest preprint, on work done as a wonderful collaboration with @mfwhite2: https://biorxiv.org/cgi/content/short/2022.11.14.516469v1 #CRISPR @biorxivpreprint

RT @Barandunlab
Very excited to share our latest published #cryoEM work on the #microsporidian #proteasome with all its proteolytic sites inhibited simultaneously by a PI31-like peptide!! Fantastic job from Nathan, Kai, Rahel, and Dennis, and collaboration with Charlie (@CT_CAES)!