For all electron microscopists out there:
"Crosshair, semi-automated targeting for electron microscopy with a motorised ultramicrotome"
Kimberly Meechan et al. 2022 @eLife from Yannick Schwab's lab at EMBL in collaboration with The Crick institute. https://elifesciences.org/articles/80899
Presents a new method for reliably and "selectively targeting small regions of interest in a resin block by trimming with an ultramicrotome", powered by "user-friendly software to convert X-ray images of resin-embedded samples into angles and cutting depths for the ultramicrotome."
Reviewed by three outstanding electron microscopists: Christel Genaud, Song Pang, and Michaela Wilsch-Bräuninger.
#electronmicroscopy #microCT #Platynereis #science #methods #EMBL #TheCrick
@albertcardona @eLife
Is it cryo? No
Is it cool though? YES!
#NotAllElectronsAreUsedInCryoEM