bioRxiv @biorxivpreprint@qoto.org

Drug discovery for heart failure targeting myosin-binding protein C https://www.biorxiv.org/content/10.1101/2023.04.03.535496v1?med=mas

TALLSorts: a T-cell acute lymphoblastic leukaemia subtype classifier using RNA-seq expression data https://www.biorxiv.org/content/10.1101/2023.04.05.535648v1?med=mas

Discovery of a new drug using lipid-based formulation targeting G12D mutated KRAS4B through non-covalent bonds https://www.biorxiv.org/content/10.1101/2023.04.05.535682v1?med=mas

Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID https://www.biorxiv.org/content/10.1101/2023.04.05.535704v1?med=mas

Methotrimeprazine exerts antiviral and neuroprotective effects in Japanese encephalitis virus infection through activation of adaptive ER stress and autophagy https://www.biorxiv.org/content/10.1101/2023.04.05.535645v1?med=mas

Identification of a Rabenosyn-5 like protein and Rab5b in host cell cytosol uptake reveals conservation of endosomal transport in malaria parasites https://www.biorxiv.org/content/10.1101/2023.04.05.535711v1?med=mas

Extensive diversity in Escherichia coli Group 3 capsules is driven by recombination and plasmid transfer from multiple species https://www.biorxiv.org/content/10.1101/2023.04.05.535558v1?med=mas

Resolvin D2-GPR18 Signaling on Myeloid Cells Limits Plaque Necrosis https://www.biorxiv.org/content/10.1101/2023.04.03.535493v1?med=mas

Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence https://www.biorxiv.org/content/10.1101/2023.04.03.535435v1?med=mas

AI-Guided Discovery of Novel SARS-CoV-2 PLpro Inhibitors: Accelerating Antiviral Drug Development in the Fight Against COVID-19 https://www.biorxiv.org/content/10.1101/2023.04.05.535700v1?med=mas

TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids https://www.biorxiv.org/content/10.1101/2023.04.03.534859v1?med=mas

Secondary Structure Detection Through Direct Nanopore RNA Sequencing https://www.biorxiv.org/content/10.1101/2023.04.05.535757v1?med=mas

Improving deep models of protein-coding potential with a Fourier-transform architecture and machine translation task https://www.biorxiv.org/content/10.1101/2023.04.03.535488v1?med=mas

Probing Altered Receptor Specificities of Antigenically Drifting Human H3N2 Viruses by Chemoenzymatic Synthesis, NMR and Modeling https://www.biorxiv.org/content/10.1101/2023.04.05.535696v1?med=mas

Increased atherosclerotic plaque and anti-oxidized low density lipoprotein in anti-Ro60 SLE autoantibody subset https://www.biorxiv.org/content/10.1101/2023.04.04.535634v1?med=mas

TcHRG plays a central role in orchestrating heme uptake in Trypanosoma cruzi epimastigotes https://www.biorxiv.org/content/10.1101/2023.04.05.535753v1?med=mas

Whole-genome sequencing confirms multiple species of Galapagos giant tortoises https://www.biorxiv.org/content/10.1101/2023.04.05.535692v1?med=mas

Metagenome mining and functional analysis reveal oxidized guanine DNA repair at the Lost City Hydrothermal Field https://www.biorxiv.org/content/10.1101/2023.04.05.535768v1?med=mas

Ziqi Dihuang decoction ameliorates thrombosis in septic rats by inhitbiting plasminogen activator inhibitor-1 https://www.biorxiv.org/content/10.1101/2023.04.05.535767v1?med=mas

Functional characterization of five triterpene synthases through De-novo assembly and transcriptome analysis of Euphorbia grantii and Euphorbia tirucalli https://www.biorxiv.org/content/10.1101/2023.04.05.535548v1?med=mas