bioRxiv @biorxivpreprint@qoto.org

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma https://www.biorxiv.org/content/10.1101/2023.04.27.538517v1?med=mas

Transcriptomic Characterization Reveals Disrupted Medium Spiny Neuron Trajectories in Huntington's Disease and Possible Therapeutic Avenues https://www.biorxiv.org/content/10.1101/2023.04.30.538872v1?med=mas

scGPT: Towards Building a Foundation Model for Single-Cell Multi-omics Using Generative AI https://www.biorxiv.org/content/10.1101/2023.04.30.538439v1?med=mas

Stomatal closure in maize is mediated by subsidiary cells and the PAN2 receptor https://www.biorxiv.org/content/10.1101/2023.04.29.538816v1?med=mas

Chemotherapy-induced intestinal injury promotes Galectin-9-driven modulation of T cell function https://www.biorxiv.org/content/10.1101/2023.04.30.538862v1?med=mas

ISRES+: An improved evolutionary strategy for function minimization to estimate the free parameters of Systems Biology models https://www.biorxiv.org/content/10.1101/2023.04.29.538818v1?med=mas

An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis https://www.biorxiv.org/content/10.1101/2023.04.30.538856v1?med=mas

Multiplexed effector screening for recognition by endogenous resistance genes using positive defense reporters in wheat protoplasts https://www.biorxiv.org/content/10.1101/2023.04.30.538885v1?med=mas

Engineering Y. lipolytica for the biosynthesis of geraniol https://www.biorxiv.org/content/10.1101/2023.04.30.538875v1?med=mas

Exploring the Role of Spatial Confinement in Immune Cell Recruitment and Regeneration of Skin Wounds https://www.biorxiv.org/content/10.1101/2023.04.30.538879v1?med=mas

Molecular crowding facilitates ribozyme-catalyzed RNA assembly https://www.biorxiv.org/content/10.1101/2023.04.30.538884v1?med=mas

A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex https://www.biorxiv.org/content/10.1101/2023.04.30.538882v1?med=mas

The establishment of HP1-independent heterochromatin reveals an essential role for HP1 proteins in maintaining epigenetic memory https://www.biorxiv.org/content/10.1101/2023.04.30.538869v1?med=mas

gcplyr: an R package for microbial growth curve data analysis https://www.biorxiv.org/content/10.1101/2023.04.30.538883v1?med=mas

The LRRK2 kinase substrates Rab8a and Rab10 contribute complementary but distinct disease-relevant phenotypes in human neurons https://www.biorxiv.org/content/10.1101/2023.04.30.538317v1?med=mas

Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease https://www.biorxiv.org/content/10.1101/2023.04.30.537820v1?med=mas

Anaplastic Thyroid Cancer Cells Upregulate Mitochondrial One-Carbon Metabolism To Meet Purine Demand, Eliciting A Critical Targetable Vulnerability https://www.biorxiv.org/content/10.1101/2023.04.30.538848v1?med=mas

Learning to Adapt - Deep Reinforcement Learning in Treatment-Resistant Prostate Cancer https://www.biorxiv.org/content/10.1101/2023.04.28.538766v1?med=mas

SimpliPyTEM: An open-source Python library and app to simplify Transmission Electron Microscopy and in situ-TEM image analysis. https://www.biorxiv.org/content/10.1101/2023.04.28.538777v1?med=mas

Bioelectronic Zeitgebers: targeted neuromodulation to re-establish circadian rhythms. https://www.biorxiv.org/content/10.1101/2023.04.30.538861v1?med=mas