bioRxiv @biorxivpreprint@qoto.org

Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development https://www.biorxiv.org/content/10.1101/2023.06.06.542948v1?med=mas

Motile bacteria leverage bioconvection for eco-physiological benefits in a natural aquatic environment https://www.biorxiv.org/content/10.1101/2023.06.06.543831v1?med=mas

The microbial derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota https://www.biorxiv.org/content/10.1101/2023.06.06.543867v1?med=mas

MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting https://www.biorxiv.org/content/10.1101/2023.06.05.543499v1?med=mas

Evaluation of haplotype-aware long-read error correction with hifieval https://www.biorxiv.org/content/10.1101/2023.06.05.543788v1?med=mas

Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5 https://www.biorxiv.org/content/10.1101/2023.06.06.543850v1?med=mas

Structural insights into the initiation of free radical formation in the Class Ib ribonucleotide reductases https://www.biorxiv.org/content/10.1101/2023.06.06.543845v1?med=mas

Structural Basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB https://www.biorxiv.org/content/10.1101/2023.06.06.543881v1?med=mas

In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair https://www.biorxiv.org/content/10.1101/2023.06.07.543977v1?med=mas

The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with chemokine CXCL12 https://www.biorxiv.org/content/10.1101/2023.06.06.543836v1?med=mas

Crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion https://www.biorxiv.org/content/10.1101/2023.06.05.543797v1?med=mas

Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population https://www.biorxiv.org/content/10.1101/2023.06.06.543983v1?med=mas

Atypical Chemokine Receptor 1 (Ackr1)-deficient Mice Resist Lethal SARS-CoV-2 Challenge https://www.biorxiv.org/content/10.1101/2023.06.05.543759v1?med=mas

Effects of growth feedback on gene circuits: A dynamical understanding https://www.biorxiv.org/content/10.1101/2023.06.06.543915v1?med=mas

Data-driven recombination detection in viral genomes https://www.biorxiv.org/content/10.1101/2023.06.05.543733v1?med=mas

Identification of Therapeutic Leads from Ficus hispida Fruit Phytochemicals against Prostate Cancer Using Pharmacoinformatic and Molecular Dynamics Simulation Approach https://www.biorxiv.org/content/10.1101/2023.06.04.543596v1?med=mas

Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus https://www.biorxiv.org/content/10.1101/2023.06.06.543855v1?med=mas

Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity https://www.biorxiv.org/content/10.1101/2023.06.06.543969v1?med=mas

Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies https://www.biorxiv.org/content/10.1101/2023.06.06.543529v1?med=mas

Interleukin-21 Drives a Hypermetabolic State and CD4+ T Cell-associated Pathogenicity in Chronic Intestinal Inflammation https://www.biorxiv.org/content/10.1101/2023.06.02.543518v1?med=mas