bioRxiv @biorxivpreprint@qoto.org

Highly effective gene inactivation in tetraploid Xenopus laevis with low-temperature-active engineered Cas12a https://www.biorxiv.org/content/10.1101/2023.07.30.550813v1?med=mas

Global decoupling of cell differentiation from cell division in early embryo development https://www.biorxiv.org/content/10.1101/2023.07.29.551123v1?med=mas

Accounting for genetic effect heterogeneity in fine-mapping and improving power to detect gene-environment interactions with SharePro https://www.biorxiv.org/content/10.1101/2023.07.27.550862v1?med=mas

AlphaFold2 modeling and molecular dynamics simulations of an intrinsically disordered protein https://www.biorxiv.org/content/10.1101/2023.07.29.551023v1?med=mas

A multiplex, prime editing framework for identifying drug resistance variants at scale https://www.biorxiv.org/content/10.1101/2023.07.27.550902v1?med=mas

Genetic Architectures of Medical Images Revealed by Registration and Fusion of Multiple Modalities https://www.biorxiv.org/content/10.1101/2023.07.27.550885v1?med=mas

Analysis of human BBS protein homologues in insects support alternative non-ciliary functions https://www.biorxiv.org/content/10.1101/2023.07.28.550953v1?med=mas

Ploidy-specific transcriptomes shed light on the heterogeneous identity and metabolism of developing pericarp cells https://www.biorxiv.org/content/10.1101/2023.07.28.550816v1?med=mas

The molecular mechanism of positive allosteric modulation at the dopamine D1 receptor https://www.biorxiv.org/content/10.1101/2023.07.27.550907v1?med=mas

Transfer learning to leverage larger datasets for improved prediction of protein stability changes https://www.biorxiv.org/content/10.1101/2023.07.27.550881v1?med=mas

Unraveling cell differentiation mechanisms through topological exploration of single-cell developmental trajectories https://www.biorxiv.org/content/10.1101/2023.07.28.551057v1?med=mas

Picky with peakpicking: assessing chromatographic peak quality with simple metrics in metabolomics https://www.biorxiv.org/content/10.1101/2023.07.28.551024v1?med=mas

The shared ancestry between the C9orf72 hexanucleotide repeat expansion and intermediate-length alleles using haplotype sharing trees and HAPTK https://www.biorxiv.org/content/10.1101/2023.07.28.550820v1?med=mas

Evolutionary signatures of human cancers revealed via genomic analysis of over 35,000 patients https://www.biorxiv.org/content/10.1101/2023.07.27.550506v1?med=mas

Multiplexed functional assessments of MYH7 variants in human cardiomyocytes at scale https://www.biorxiv.org/content/10.1101/2023.07.28.551073v1?med=mas

Dynamic simulations of feeding and respiration of the early Cambrian periderm-bearing cnidarian polyps https://www.biorxiv.org/content/10.1101/2023.07.28.550931v1?med=mas

Mining threats in high-level biodiversity conservation policies https://www.biorxiv.org/content/10.1101/2023.07.30.550308v1?med=mas

Predictive microbial community changes across a temperature gradient https://www.biorxiv.org/content/10.1101/2023.07.28.550899v1?med=mas

Modeling time-varying phytoplankton subsidy reveals at-risk species in a Chilean intertidal ecosystem https://www.biorxiv.org/content/10.1101/2023.07.27.550852v1?med=mas

Functional traits fail to predict long-term responses to climate change https://www.biorxiv.org/content/10.1101/2023.07.27.550868v1?med=mas