bioRxiv @biorxivpreprint@qoto.org

Integrative proteomics and transcriptomics of human T-cells reveals temporal metabolic reprogramming following TCR-induced activation https://www.biorxiv.org/content/10.1101/2023.03.17.532022v1?med=mas

Ensemble and Iterative Engineering for Maximized Bioconversion to the Blue Pigment, Indigoidine from Non-Canonical Sustainable Carbon Sources https://www.biorxiv.org/content/10.1101/2023.03.16.532821v1?med=mas

MultiomicsTracks96: A high throughput PIXUL-Matrix-based toolbox to profile frozen and FFPE tissues multiomes https://www.biorxiv.org/content/10.1101/2023.03.16.533031v1?med=mas

The vasodilator-stimulated phosphoprotein (VASP) supports the conduction of vasodilator signals and NO-induced arteriolar dilations in murine arterioles in vivo https://www.biorxiv.org/content/10.1101/2023.03.17.533095v1?med=mas

COMT inhibitor tolcapone represses the migration and invasion of trophoblast and results in preeclampsia-like phenotypes in mice https://www.biorxiv.org/content/10.1101/2023.03.17.530517v1?med=mas

Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy https://www.biorxiv.org/content/10.1101/2023.03.17.533056v1?med=mas

Leptomeningeal anti-tumor immunity follows unique signaling principles https://www.biorxiv.org/content/10.1101/2023.03.17.533041v1?med=mas

Two-fluid dynamics and micron-thin boundary layers shape cytoplasmic flows in early Drosophila embryos https://www.biorxiv.org/content/10.1101/2023.03.16.532979v1?med=mas

Mitigation of membrane morphology defects explain stability and orientational specificity of CLC dimers https://www.biorxiv.org/content/10.1101/2023.03.16.533024v1?med=mas

Effect of cell membrane tension on the lifetime and size of mature clathrin-coated pits and their spatial distribution https://www.biorxiv.org/content/10.1101/2023.03.16.532501v1?med=mas

Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution https://www.biorxiv.org/content/10.1101/2023.03.16.533055v1?med=mas

Mechanism of defibrillation of cardiac tissue by periodic low-energy pacing https://www.biorxiv.org/content/10.1101/2023.03.16.533010v1?med=mas

The ATP-bound State of the Uncoupling Protein 1 (UCP1) from Molecular Simulations https://www.biorxiv.org/content/10.1101/2023.03.17.533074v1?med=mas

PhyloSophos: a high-throughput scientific name mapping algorithm augmented with explicit consideration of taxonomic science https://www.biorxiv.org/content/10.1101/2023.03.17.533059v1?med=mas

An interpretable, finite sample valid alternative to Pearson's X2 for scientific discovery https://www.biorxiv.org/content/10.1101/2023.03.16.533008v1?med=mas

On quantum computing and geometry optimization https://www.biorxiv.org/content/10.1101/2023.03.16.532929v1?med=mas

Rigid Scaffolds are Promising for Designing Macrocyclic Kinase Inhibitors https://www.biorxiv.org/content/10.1101/2023.03.17.533119v1?med=mas

Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles https://www.biorxiv.org/content/10.1101/2023.03.17.533081v1?med=mas

A flexible implant for acute intrapancreatic electrophysiology https://www.biorxiv.org/content/10.1101/2023.03.17.532901v1?med=mas

Comparative genomic analysis identifies great-ape-specific structural variants and their evolutionary significance https://www.biorxiv.org/content/10.1101/2023.03.16.533043v1?med=mas