bioRxiv @biorxivpreprint@qoto.org

Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity https://www.biorxiv.org/content/10.1101/2023.05.22.541809v1?med=mas

SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter https://www.biorxiv.org/content/10.1101/2023.05.22.541801v1?med=mas

Higher-order assembly is a regulatory switch that promotes outer kinetochore recruitment https://www.biorxiv.org/content/10.1101/2023.05.22.541649v1?med=mas

Extracellular G-quadruplex and Z-DNA protect biofilms from DNase I and forms a DNAzyme with peroxidase activity https://www.biorxiv.org/content/10.1101/2023.05.22.541711v1?med=mas

Dynamic enhancer interactome promotes senescence and aging https://www.biorxiv.org/content/10.1101/2023.05.22.541769v1?med=mas

Discovery of new deaminase functions by structure-based protein clustering https://www.biorxiv.org/content/10.1101/2023.05.21.541555v1?med=mas

N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules https://www.biorxiv.org/content/10.1101/2023.05.22.541693v1?med=mas

Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease. https://www.biorxiv.org/content/10.1101/2023.05.22.541727v1?med=mas

Decryption of sequence, structure, and functional features of SINE repeat elements in SINEUP non-coding RNA-mediated post-transcriptional gene regulation https://www.biorxiv.org/content/10.1101/2023.05.22.541671v1?med=mas

Distinct roles of LARP1 and 4EBP1/2 in regulating translation and stability of 5'TOP mRNAs https://www.biorxiv.org/content/10.1101/2023.05.22.541712v1?med=mas

Identification of an anti-CRISPR protein that inhibits the CRISPR-Cas type I-B system in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2023.05.22.541795v1?med=mas

Critical residues of the antibiotic peptide LysM that inhibits lipid II flipping https://www.biorxiv.org/content/10.1101/2023.05.22.541694v1?med=mas

High prevalence of Bovine Tuberculosis reported in Cattle and Buffalo of Eastern Nepal https://www.biorxiv.org/content/10.1101/2023.05.21.541660v1?med=mas

Muscle-specific MEF2D alpha 2 isoform regulates mice exercise capacity, muscle ketolysis, and systemic ketone body availability in mice https://www.biorxiv.org/content/10.1101/2023.05.22.540988v1?med=mas

Physiological Responses of The Leaves of a High-Altitude Plant Picrorhiza kurroa to Cold Stress https://www.biorxiv.org/content/10.1101/2023.05.21.541615v1?med=mas

Markov State Models and Perturbation-Based Approaches Reveal Distinct Dynamic Signatures and Hidden Allosteric Pockets in the Emerging SARS-Cov-2 Spike Omicron Variants Complexes with the Host Receptor: The Interplay of Dynamics and Convergent Evolution Modulates Allostery and Functional Mechanisms https://www.biorxiv.org/content/10.1101/2023.05.20.541592v1?med=mas

preon: Fast and accurate entity normalization for drug names and cancer types in precision oncology https://www.biorxiv.org/content/10.1101/2023.05.22.540912v1?med=mas

An Atlas of Adaptive Evolution in Endemic Human Viruses https://www.biorxiv.org/content/10.1101/2023.05.19.541367v1?med=mas

Massive invasion of organellar DNA drives nuclear genome evolution in Toxoplasma https://www.biorxiv.org/content/10.1101/2023.05.22.539837v1?med=mas

Small extracellular vesicles but not microvesicles from Opisthorchis viverrini promote cell proliferation in human cholangiocytes. https://www.biorxiv.org/content/10.1101/2023.05.22.540805v1?med=mas