bioRxiv @biorxivpreprint@qoto.org

Machine learning of enhancer-promoter specificity based on enhancer perturbation studies reveals a distinct class of enhancers. https://www.biorxiv.org/content/10.1101/2023.06.30.547290v1?med=mas

Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample https://www.biorxiv.org/content/10.1101/2023.06.30.547175v1?med=mas

Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils https://www.biorxiv.org/content/10.1101/2023.06.29.547125v1?med=mas

The successor representation subserves hierarchical abstraction for goal-directed behavior https://www.biorxiv.org/content/10.1101/2023.06.30.547163v1?med=mas

Automated Microbial Classification System based on Deep Convolutional Neural Networks using Images from Colony Picker https://www.biorxiv.org/content/10.1101/2023.06.29.547155v1?med=mas

FruitFire: a luciferase based on a fruit fly metabolic enzyme https://www.biorxiv.org/content/10.1101/2023.06.30.547126v1?med=mas

Efficient Formation of Single-copy Human Artificial Chromosomes https://www.biorxiv.org/content/10.1101/2023.06.30.547284v1?med=mas

Amazing structural diversity of giant virus-like particles in forest soil https://www.biorxiv.org/content/10.1101/2023.06.30.546935v1?med=mas

Cross-species transmission and PB2 mammalian adaptations of highly pathogenic avian influenza A/H5N1 viruses in Chile https://www.biorxiv.org/content/10.1101/2023.06.30.547205v1?med=mas

Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders https://www.biorxiv.org/content/10.1101/2023.06.30.547254v1?med=mas

A Rationally Designed Antimicrobial Peptide from Structural and Functional Insight of Clostridium difficile Translation Initiation Factor 1 https://www.biorxiv.org/content/10.1101/2023.06.30.547268v1?med=mas

TREX reveals proteins that bind to specific RNA regions in living cells https://www.biorxiv.org/content/10.1101/2023.06.30.547259v1?med=mas

HOXDeRNA activates a cancerous transcription program and super-enhancers genome-wide https://www.biorxiv.org/content/10.1101/2023.06.30.547275v1?med=mas

Carbon source and surface type influence the early-stage biofilm formation by rhizosphere bacterium Pseudomonas donghuensis P482. https://www.biorxiv.org/content/10.1101/2023.06.30.547207v1?med=mas

Decomposing a San Francisco Estuary microbiome using long read metagenomics reveals species and species- and strain-level dominance from picoeukaryotes to viruses https://www.biorxiv.org/content/10.1101/2023.06.30.547288v1?med=mas

How Myosin VI Traps its Off-State, is Activated and Dimerizes https://www.biorxiv.org/content/10.1101/2023.06.30.547185v1?med=mas

Co-translational ribosome pairing enables native assembly of misfolding-prone subunits https://www.biorxiv.org/content/10.1101/2023.06.30.547139v1?med=mas

Engineering transposon-associated TnpB-1 ωRNA system for efficient gene editing and disease treatment in mouse https://www.biorxiv.org/content/10.1101/2023.06.29.547137v1?med=mas

Chemogenetic profiling of ubiquitin-like modifier pathways identifies NFATC2IP as a mediator of SUMO-dependent genome integrity https://www.biorxiv.org/content/10.1101/2023.06.30.547196v1?med=mas

Wound microbiota-mediated correction of matrix metalloproteinase expression promotes re-epithelialization of diabetic wounds https://www.biorxiv.org/content/10.1101/2023.06.30.547263v1?med=mas