bioRxiv @biorxivpreprint@qoto.org

Internet-connected cortical organoids for project-based stem cell and neuroscience education https://www.biorxiv.org/content/10.1101/2023.07.13.546418v1?med=mas

shRNA drop-out screen identifies BRD4 targeting transcription from RNA polymerase II system to activate β-catenin to promote soft-tissue tumor proliferations https://www.biorxiv.org/content/10.1101/2023.07.14.548690v1?med=mas

Phosphorylation modulates estrogen receptor disorder by altering long-range hydrophobic interactions https://www.biorxiv.org/content/10.1101/2023.07.14.548966v1?med=mas

Tyk2-mediated signaling promotes the development of autoreactive CD8+ CTLs and autoimmune type 1 diabetes https://www.biorxiv.org/content/10.1101/2023.07.14.548984v1?med=mas

Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin https://www.biorxiv.org/content/10.1101/2023.07.14.549089v1?med=mas

Totally tubular: ASO-mediated knock-down of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages https://www.biorxiv.org/content/10.1101/2023.07.14.549028v1?med=mas

Unveiling the role of SRY in male-biased cancers: Insights into the molecular basis of sex disparities in high-grade glioma and melanoma https://www.biorxiv.org/content/10.1101/2023.07.14.548747v1?med=mas

Microstructure-Based Modeling of Primary Cilia Mechanics https://www.biorxiv.org/content/10.1101/2023.07.14.549117v1?med=mas

A bespoke analytical workflow for the confident identification of sulfopeptides and their discrimination from phosphopeptides https://www.biorxiv.org/content/10.1101/2023.07.15.549150v1?med=mas

Structural basis for ssDNA-activated NADase activity of the prokaryotic SPARTA immune system https://www.biorxiv.org/content/10.1101/2023.07.14.549122v1?med=mas

A high-quality reference genome for the common creek chub, Semotilus atromaculatus https://www.biorxiv.org/content/10.1101/2023.07.14.549000v1?med=mas

KDM4-dependent DNA breaks at active promoters facilitate +1 nucleosome eviction https://www.biorxiv.org/content/10.1101/2023.07.14.548993v1?med=mas

Rewiring the carbon cycle: a theoretical framework for animal-driven ecosystem carbon sequestration https://www.biorxiv.org/content/10.1101/2023.07.14.549071v1?med=mas

Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation https://www.biorxiv.org/content/10.1101/2023.07.15.549120v1?med=mas

Relationship Between Domain and Function of the Yeast RNase T2, Rny1p, Which Mediates rRNA Degradation upon Starvation https://www.biorxiv.org/content/10.1101/2023.07.14.548783v1?med=mas

In silico characterization and phylogenetic analysis of Elaeocarpus ganitrus based on ITS2 barcode sequence https://www.biorxiv.org/content/10.1101/2023.07.15.549003v1?med=mas

Surrogate selection oversamples expanded T cell clonotypes https://www.biorxiv.org/content/10.1101/2023.07.13.548950v1?med=mas

PEP-Patch: Electrostatics in Protein-Protein Recognition, Specificity and Antibody Developability https://www.biorxiv.org/content/10.1101/2023.07.14.547811v1?med=mas

TriTan: An efficient triple non-negative matrix factorisation method for integrative analysis of single-cell multiomics data https://www.biorxiv.org/content/10.1101/2023.07.14.549059v1?med=mas

Co-adaptation improves performance in a dynamic human-machine interface https://www.biorxiv.org/content/10.1101/2023.07.14.549053v1?med=mas