bioRxiv @biorxivpreprint@qoto.org

Small Molecule Screen Identifies Pyrimethamine as an Inhibitor of NRF2-driven Esophageal Hyperplasia https://www.biorxiv.org/content/10.1101/2022.12.05.519147v1?med=mas

SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status https://www.biorxiv.org/content/10.1101/2022.12.06.519395v1?med=mas

Parameter estimation and identifiability analysis for a bivalent analyte model of monoclonal antibody-antigen binding https://www.biorxiv.org/content/10.1101/2022.12.05.519088v1?med=mas

Spatial frequency-based correction of the spherical aberration in living brain imaging https://www.biorxiv.org/content/10.1101/2022.12.05.519048v1?med=mas

A Meta-analysis of 2D vs. 3D Ovarian Cancer Cellular Models https://www.biorxiv.org/content/10.1101/2022.12.05.519144v1?med=mas

M-Band Wavelet-Based Imputation of scRNA-seq Matrix and Multi-view Clustering of Cell https://www.biorxiv.org/content/10.1101/2022.12.05.519090v1?med=mas

Application of Physiological and Pathological Wall Shear Stress to Endocardial Endothelial Cells Triggers Complex Signaling Pathways https://www.biorxiv.org/content/10.1101/2022.12.05.519049v1?med=mas

Structure of an endogenous mycobacterial MCE lipid transporter https://www.biorxiv.org/content/10.1101/2022.12.08.519548v1?med=mas

Autorepression-based conditional gene expression system in yeast for variation-suppressed control of protein dosage https://www.biorxiv.org/content/10.1101/2022.12.05.519107v1?med=mas

Expanding the HDAC druggable landscape beyond enzymatic inhibition https://www.biorxiv.org/content/10.1101/2022.12.07.519454v1?med=mas

Gallocin A, an atypical two-peptide bacteriocin secreted by Streptococcus gallolyticus subsp. gallolyticus https://www.biorxiv.org/content/10.1101/2022.12.05.519244v1?med=mas

Inducible CRISPRi-based operon silencing and selective in trans gene complementation in Borrelia burgdorferi https://www.biorxiv.org/content/10.1101/2022.12.05.519228v1?med=mas

The two-component system CroRS regulates isoprenoid flux to mediate antimicrobial tolerance in the bacterial pathogen Enterococcus faecalis https://www.biorxiv.org/content/10.1101/2022.12.05.519242v1?med=mas

Engineered superinfective Pf phage prevents dissemination of Pseudomonas aeruginosa in a mouse burn model https://www.biorxiv.org/content/10.1101/2022.12.05.519246v1?med=mas

Optogenetic activation of visual thalamus generates artificial visual percepts https://www.biorxiv.org/content/10.1101/2022.12.07.519434v1?med=mas

Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration after peripheral nerve injury https://www.biorxiv.org/content/10.1101/2022.12.07.519441v1?med=mas

Low-pass sequencing plus imputation using avidity sequencing displays comparable imputation accuracy to sequencing by synthesis while reducing duplicates https://www.biorxiv.org/content/10.1101/2022.12.07.519512v1?med=mas

Neutrophil-driven cardiac damage during invasive Streptococcus pneumoniae infection is regulated by CD73 https://www.biorxiv.org/content/10.1101/2022.12.07.519499v1?med=mas

Inductive biases of neural networks for generalization in spatial navigation https://www.biorxiv.org/content/10.1101/2022.12.07.519515v1?med=mas

A rapid phylogeny-based method for accurate community profiling of large-scale metabarcoding datasets https://www.biorxiv.org/content/10.1101/2022.12.06.519402v1?med=mas