Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors https://www.biorxiv.org/content/10.1101/2023.02.01.526549v1?med=mas
High-content image-based CRISPR screening reveals regulators of 3D genome architectures https://www.biorxiv.org/content/10.1101/2023.01.31.525983v1?med=mas
Comparative genomics of novel Bacteroides acidifaciens isolates reveals candidates for adaptation to host subspecies in house mice https://www.biorxiv.org/content/10.1101/2023.01.31.526425v1?med=mas
The source of microbial transmission influences niche colonization and microbiome development https://www.biorxiv.org/content/10.1101/2023.01.31.526426v1?med=mas
Physical contacts between sparse biofilms promote plasmid transfer and generate functional novelty https://www.biorxiv.org/content/10.1101/2023.02.01.526699v1?med=mas
Comprehensive mutagenesis maps the effect of all single codon mutations in the AAV2 rep gene on AAV production https://www.biorxiv.org/content/10.1101/2023.01.31.526541v1?med=mas
Metaproteomic analysis of nasopharyngeal swab samples to identify microbial peptides and potential co-infection status in COVID-19 patients https://www.biorxiv.org/content/10.1101/2023.01.31.525328v1?med=mas
Gnotobiotic zebrafish microbiota display inter-individual variability affecting host physiology https://www.biorxiv.org/content/10.1101/2023.02.01.526612v1?med=mas
Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation https://www.biorxiv.org/content/10.1101/2023.02.01.526589v1?med=mas
Functional assignment of gut-specific archaeal proteins in the human gut microbiome https://www.biorxiv.org/content/10.1101/2023.02.01.526569v1?med=mas
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation. https://www.biorxiv.org/content/10.1101/2023.02.01.526586v1?med=mas
Integrase-associated niche differentiation of endogenous large DNA viruses in crustaceans https://www.biorxiv.org/content/10.1101/2023.01.31.526539v1?med=mas
Host-microbiome transplants of the schistosome snail host Biomphalaria glabrata reflect species-specific associations https://www.biorxiv.org/content/10.1101/2023.02.01.526614v1?med=mas
An integrative and multi-indicator approach for wildlife health applied to an endangered caribou herd https://www.biorxiv.org/content/10.1101/2023.02.01.526641v1?med=mas
The biocide triclosan induces (p)ppGpp dependent antibiotic tolerance and alters SarA dependent biofilm structures in Staphylococcus aureus https://www.biorxiv.org/content/10.1101/2023.02.01.525840v1?med=mas
Segregational drift hinders the evolution of antibiotic resistance on polyploid replicons https://www.biorxiv.org/content/10.1101/2023.02.01.526651v1?med=mas
SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner https://www.biorxiv.org/content/10.1101/2023.02.01.526580v1?med=mas
Genetic profiling of Plasmodium ovale wallikeri relapses with microsatellite markers and whole-genome sequencing https://www.biorxiv.org/content/10.1101/2023.02.01.526392v1?med=mas
Bacterial toxin-antitoxin system MazEF as a native defense mechanism against RNA phages in Escherichia coli https://www.biorxiv.org/content/10.1101/2023.02.01.526697v1?med=mas
Insights into the mechanism of mycelium transformation of Streptomyces toxytricini into pellet https://www.biorxiv.org/content/10.1101/2023.02.01.526547v1?med=mas
The non-profit preprint server for the life sciences