bioRxiv @biorxivpreprint@qoto.org

Discovery and Validation of RUNX1 DNA Methylation in Differentiating Papillary Thyroid Cancer from Benign Nodules https://www.biorxiv.org/content/10.1101/2023.04.10.536270v1?med=mas

Targeting ABCB4 using mRNA-LNP for the treatment of rare liver diseases https://www.biorxiv.org/content/10.1101/2023.04.11.535868v1?med=mas

The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery https://www.biorxiv.org/content/10.1101/2023.04.11.536453v1?med=mas

Molecular Detection and Parasite Load Determination of Leishmania donovani in Dogs at Humera and Sheraro, Western Tigray, Ethiopia https://www.biorxiv.org/content/10.1101/2023.04.10.536327v1?med=mas

A comprehensive catalog with 100 million genes and 3,000 metagenome-assembled genomes from global cold seep sediments https://www.biorxiv.org/content/10.1101/2023.04.10.536201v1?med=mas

Redundant and distinct roles of two 14-3-3 proteins in Fusarium sacchari, pathogen of sugarcane Pokkah boeng disease https://www.biorxiv.org/content/10.1101/2023.04.10.536328v1?med=mas

Touching the (almost) untouchable: a minimally-invasive workflow for microbiological and biomolecular analyses of cultural heritage objects https://www.biorxiv.org/content/10.1101/2023.04.11.536414v1?med=mas

Identification of microbial communities and their removal efficiency of multiple pharmaceutical micropollutants combined in Membrane-Bioreactors https://www.biorxiv.org/content/10.1101/2023.04.11.536351v1?med=mas

Increased membrane fluidity and cell wall thickening contribute to high-level daptomycin resistance in S. aureus with defective pgsA and yycG https://www.biorxiv.org/content/10.1101/2023.04.11.536441v1?med=mas

Quantification of Rho-termination in vivo using qRT-PCR: a comprehensive analysis https://www.biorxiv.org/content/10.1101/2023.04.11.536429v1?med=mas

Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage https://www.biorxiv.org/content/10.1101/2023.04.11.536265v1?med=mas

The Circulation of Metabolites in the Outer Retina https://www.biorxiv.org/content/10.1101/2023.04.10.536306v1?med=mas

Sucrose phosphorylase from Alteromonas mediterranea: structural insight into the regioselective α-glucosylation of (+)-catechin https://www.biorxiv.org/content/10.1101/2023.04.11.536264v1?med=mas

In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament https://www.biorxiv.org/content/10.1101/2023.04.11.536387v1?med=mas

Computational design of Matrix Metalloprotenaise-9 (MMP-9) resistant to auto-cleavage https://www.biorxiv.org/content/10.1101/2023.04.11.536383v1?med=mas

Cooperative dynamics of DNA grafted magnetic nanoparticles optimize magnetic biosensing and coupling to DNA origami https://www.biorxiv.org/content/10.1101/2023.04.11.536349v1?med=mas

Mutation signature filtering enables high-fidelity RNA structure probing at all four nucleobases with DMS https://www.biorxiv.org/content/10.1101/2023.04.10.536308v1?med=mas

Syncytiotrophoblast 5'-tRNA fragments are placental endocrine signals contributing to sterile inflammation in preeclampsia https://www.biorxiv.org/content/10.1101/2023.04.11.536371v1?med=mas

BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair https://www.biorxiv.org/content/10.1101/2023.04.11.536470v1?med=mas

Physical interaction between MSL2 and CLAMP assures direct cooperativity and prevents competition at composite binding sites https://www.biorxiv.org/content/10.1101/2023.04.11.536365v1?med=mas