bioRxiv @biorxivpreprint@qoto.org

T cell landscape definition by multi-omics identifies Galectin-9 as novel immunotherapy target in chronic lymphocytic leukemia https://www.biorxiv.org/content/10.1101/2022.12.15.519719v1?med=mas

Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell development https://www.biorxiv.org/content/10.1101/2022.12.15.520535v1?med=mas

Parahippocampal neurons encode task-relevant information for goal-directed navigation https://www.biorxiv.org/content/10.1101/2022.12.15.520660v1?med=mas

Enhancer-driven gene regulatory networks inference from single-cell RNA-seq and ATAC-seq data https://www.biorxiv.org/content/10.1101/2022.12.15.520582v1?med=mas

Truncating ASXL1 mutations in Bohring-Opitz Syndrome dysregulate canonical and non-canonical Wnt Signaling https://www.biorxiv.org/content/10.1101/2022.12.15.520167v1?med=mas

Human retina trades single-photon detection for high-fidelity contrast encoding https://www.biorxiv.org/content/10.1101/2022.12.15.520020v1?med=mas

Grid cell disruption in a mouse model of early Alzheimer's disease reflects reduced integration of self-motion cues and increased influence of environmental geometry https://www.biorxiv.org/content/10.1101/2022.12.15.520595v1?med=mas

Monitoring RNA restructuring in a human cell-free extract reveals eIF4A-dependent and eIF4A-independent unwinding activity. https://www.biorxiv.org/content/10.1101/2022.12.14.520460v1?med=mas

State-dependency of behavioural traits is a function of the life-stage in a holometabolous insect https://www.biorxiv.org/content/10.1101/2022.12.15.520519v1?med=mas

Cryo-EM structures of chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir https://www.biorxiv.org/content/10.1101/2022.12.15.520545v1?med=mas

Perceptual awareness is gradual in temporal and dichotomous in fronto-parietal cortices https://www.biorxiv.org/content/10.1101/2022.12.14.520410v1?med=mas

A differential effect for tau isoforms and mutants in decreasing the stability of Arc https://www.biorxiv.org/content/10.1101/2022.12.15.520620v1?med=mas

Is mild ADHD beneficial: Brain criticality is maximal with moderate ADHD symptom scores https://www.biorxiv.org/content/10.1101/2022.12.14.519751v1?med=mas

Stabilization of V1 interneuron-motor neuron connectivity ameliorates motor phenotype in a mouse model of ALS https://www.biorxiv.org/content/10.1101/2022.12.15.520568v1?med=mas

Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain https://www.biorxiv.org/content/10.1101/2022.12.14.520294v1?med=mas

Functional dissociations between prefrontal and parietal cortex during task switching: A combined fMRI and TMS study https://www.biorxiv.org/content/10.1101/2022.12.15.520659v1?med=mas

Genomic loci involved in sensing environmental cues and metabolism affect seasonal coat shedding in Bos taurus and Bos indicus cattle https://www.biorxiv.org/content/10.1101/2022.12.14.520472v1?med=mas

The Kelch13 compartment is a hub of highly divergent vesicle trafficking proteins in malaria parasites https://www.biorxiv.org/content/10.1101/2022.12.15.520209v1?med=mas

PSYLLIUM FIBER PROTECTS MICE AGAINST WESTERN DIET-INDUCED METABOLIC SYNDROME VIA MICROBIOTA-DEPENDENT MECHANISM https://www.biorxiv.org/content/10.1101/2022.12.15.520605v1?med=mas

Diversity and pathobiology of an ilarvirus unexpectedly detected in diverse host plants and in global sequencing data https://www.biorxiv.org/content/10.1101/2022.12.15.520526v1?med=mas