bioRxiv @biorxivpreprint@qoto.org

Inhibition of pyrimidine synthesis in murine skin wounds induces a pyoderma gangrenosum-like neutrophilic dermatosis accompanied by spontaneous gut inflammation https://www.biorxiv.org/content/10.1101/2022.12.20.521286v1?med=mas

Designing epitope-focused vaccines via antigen reorientation https://www.biorxiv.org/content/10.1101/2022.12.20.521291v1?med=mas

Hypothalamic supramammillary neurons that project to the medial septum control wakefulness https://www.biorxiv.org/content/10.1101/2022.12.20.521335v1?med=mas

Haplotype resolved chromosome level genome assembly of Citrus australis reveals disease resistance and other citrus specific genes https://www.biorxiv.org/content/10.1101/2022.12.20.521315v1?med=mas

Scoring thermal limits in small insects using open-source, computer assisted motion detection. https://www.biorxiv.org/content/10.1101/2022.12.20.521307v1?med=mas

Benchmarking single-cell hashtag oligo demultiplexing methods https://www.biorxiv.org/content/10.1101/2022.12.20.521313v1?med=mas

Multimodal learning of noncoding variant effects using genome sequence and chromatin structure https://www.biorxiv.org/content/10.1101/2022.12.20.521331v1?med=mas

LuxHMM: DNA methylation analysis with genome segmentation via Hidden Markov Model https://www.biorxiv.org/content/10.1101/2022.12.20.521327v1?med=mas

End-to-end protein-ligand complex structure generation with diffusion-based generative models https://www.biorxiv.org/content/10.1101/2022.12.20.521309v1?med=mas

STrack: A tool to Simply Track bacterial cells in microscopy time-lapse images https://www.biorxiv.org/content/10.1101/2022.12.20.521337v1?med=mas

Supervised discovery of interpretable gene programs from single-cell data https://www.biorxiv.org/content/10.1101/2022.12.20.521311v1?med=mas

A novel performance scoring quantification framework for stress test set-ups https://www.biorxiv.org/content/10.1101/2022.12.21.521346v1?med=mas

Bacillus subtilis encodes a discrete flap endonuclease that cleaves RNA-DNA hybrids https://www.biorxiv.org/content/10.1101/2022.12.20.521345v1?med=mas

Thermal cycling-hyperthermia down-regulates liposaccharide-induced inflammatory response in human whole-blood and helps clear herpes simplex virus type 1 by U-937 macrophages https://www.biorxiv.org/content/10.1101/2022.12.20.521318v1?med=mas

Recurrent hypoxia in a rat model of sleep apnea during pregnancy leads to microglia-dependent respiratory deficits and persistent neuroinflammation in adult male offspring https://www.biorxiv.org/content/10.1101/2022.12.20.521336v1?med=mas

Likelihood-based signal and noise analysis for docking of models into cryo-EM maps https://www.biorxiv.org/content/10.1101/2022.12.20.521171v1?med=mas

Benchmark of force fields to characterize the intrinsically disordered R2-FUS-LC region https://www.biorxiv.org/content/10.1101/2022.12.20.521322v1?med=mas

Transposable element and host silencing activity in gigantic genomes https://www.biorxiv.org/content/10.1101/2022.12.20.521252v1?med=mas

Relation between pH alterations in cellular models of amyotrophic lateral sclerosis and TDP-43 protein aggregation https://www.biorxiv.org/content/10.1101/2022.12.21.521010v1?med=mas

Mismatch novelty exploration training impairs VPAC1 receptor mediated modulation of hippocampal synaptic plasticity by endogenous VIP https://www.biorxiv.org/content/10.1101/2022.12.21.521348v1?med=mas