bioRxiv @biorxivpreprint@qoto.org

Mitochondrial genes in the 22q11.2 deleted region regulate neural stem and progenitor cell proliferation https://www.biorxiv.org/content/10.1101/2023.01.03.522615v1?med=mas

An Automated Scientist to Design and Optimize Microbial Strains for the Industrial Production of Small Molecules https://www.biorxiv.org/content/10.1101/2023.01.03.521657v1?med=mas

A critical role of retinoic acid concentration for the induction of a fully human-like atrial phenotype in hiPSC-CM https://www.biorxiv.org/content/10.1101/2023.01.03.522611v1?med=mas

Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis https://www.biorxiv.org/content/10.1101/2023.01.03.522608v1?med=mas

Mammary-specific ectopic expression of mutant human GATA3 did not potentiate medroxyprogesterone acetate-driven mouse mammary tumorigenesis https://www.biorxiv.org/content/10.1101/2023.01.03.522644v1?med=mas

Cooperative NF-κB and Notch1 signaling promotes macrophage-mediated MenaINV expression in breast cancer https://www.biorxiv.org/content/10.1101/2023.01.03.522642v1?med=mas

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis https://www.biorxiv.org/content/10.1101/2023.01.03.522637v1?med=mas

Structure of pre-miR-31 reveals an active role in Dicer processing https://www.biorxiv.org/content/10.1101/2023.01.03.519659v1?med=mas

Structural mechanism of LIN28B nucleosome targeting by OCT4 for pluripotency https://www.biorxiv.org/content/10.1101/2023.01.03.522631v1?med=mas

Crystal structure of a mammalian CMTM6 and its interaction model with PD-L1 https://www.biorxiv.org/content/10.1101/2023.01.03.522599v1?med=mas

Sequence-to-sequence translation from mass spectra to peptides with a transformer model https://www.biorxiv.org/content/10.1101/2023.01.03.522621v1?med=mas

Control of atypical PKC{iota} membrane dissociation by tyrosine phosphorylation within a PB1-C1 interdomain interface https://www.biorxiv.org/content/10.1101/2023.01.03.522491v1?med=mas

Crosstalk between chromatin and the transcription factor Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage. https://www.biorxiv.org/content/10.1101/2023.01.03.522588v1?med=mas

Building pangene sets from plant genome alignments confirms presence-absence variation https://www.biorxiv.org/content/10.1101/2023.01.03.520531v1?med=mas

The genetic architecture of the human skeletal form https://www.biorxiv.org/content/10.1101/2023.01.03.521284v1?med=mas

L-shape distribution of the relative substitution rate (c micro) observed for SARS-COV-2 genome, inconsistent with the selectionist theory, the neutral theory and the nearly neutral theory but a near-neutral balanced selection theory: implication on neutralist-selectionist debate https://www.biorxiv.org/content/10.1101/2023.01.01.522435v1?med=mas

Reduced effectiveness of purifying selection on new mutations in a parthenogenic terrestrial isopod (Trichoniscus pusillus) https://www.biorxiv.org/content/10.1101/2023.01.03.522635v1?med=mas

Foraging guild modulates insectivorous bat responses to habitat loss and insular fragmentation in peninsular Malaysia https://www.biorxiv.org/content/10.1101/2023.01.03.522569v1?med=mas

The myocardium utilizes Pdgfra-PI3K signaling to steer towards the midline during heart tube formation https://www.biorxiv.org/content/10.1101/2023.01.03.522612v1?med=mas

Enhanced transmissibility of XBB.1.5 is contributed by both strong ACE2 binding and antibody evasion https://www.biorxiv.org/content/10.1101/2023.01.03.522427v1?med=mas