bioRxiv @biorxivpreprint@qoto.org

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry https://www.biorxiv.org/content/10.1101/2023.01.09.523326v1?med=mas

Evolutionary transcriptomics reveals longevity mostly driven by polygenic and indirect selection in mammals https://www.biorxiv.org/content/10.1101/2023.01.09.523139v1?med=mas

Humanized CD36 mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36 https://www.biorxiv.org/content/10.1101/2023.01.09.523279v1?med=mas

Oncogene-like addiction to aneuploidy in human cancers https://www.biorxiv.org/content/10.1101/2023.01.09.523344v1?med=mas

Six3 acts independently of Pax6 to provide an essential contribution to lens development https://www.biorxiv.org/content/10.1101/2023.01.09.523289v1?med=mas

The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size https://www.biorxiv.org/content/10.1101/2023.01.09.523369v1?med=mas

Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier https://www.biorxiv.org/content/10.1101/2023.01.10.522344v1?med=mas

N-Cadherin and alpha-catenin regulate formation of functional tunneling nanotubes https://www.biorxiv.org/content/10.1101/2023.01.10.523392v1?med=mas

A mechanism of melanogenesis mediated by E-cadherin downregulation and its involvement in solar lentigines https://www.biorxiv.org/content/10.1101/2023.01.09.523359v1?med=mas

Genome wide-analysis of anterior-posterior mRNA localization in Stentor coeruleus reveals a role for the microtubule cytoskeleton https://www.biorxiv.org/content/10.1101/2023.01.09.523364v1?med=mas

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome https://www.biorxiv.org/content/10.1101/2023.01.10.523203v1?med=mas

Polyploid yeast are dependent on elevated levels of Mps1 for successful chromosome segregation https://www.biorxiv.org/content/10.1101/2023.01.09.523325v1?med=mas

Neural phoneme discrimination in variable speech in newborns; associations with dyslexia risk and later language skills https://www.biorxiv.org/content/10.1101/2023.01.10.522962v1?med=mas

Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis https://www.biorxiv.org/content/10.1101/2023.01.10.523252v1?med=mas

A class-specific effect of dysmyelination on the excitability of hippocampal interneurons https://www.biorxiv.org/content/10.1101/2023.01.10.523413v1?med=mas

The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I https://www.biorxiv.org/content/10.1101/2023.01.08.523166v1?med=mas

Novel artificial selection method improves function of simulated microbial communities https://www.biorxiv.org/content/10.1101/2023.01.08.523165v1?med=mas

Localized modulation of DNA supercoiling, triggered by the Shigella anti-silencer VirB, is sufficient to relieve H-NS-mediated silencing https://www.biorxiv.org/content/10.1101/2023.01.09.523335v1?med=mas

CXCL13 levels in cerebrospinal fluids of patients with multiple sclerosis: The role of Borrelia proteins in neuro infections https://www.biorxiv.org/content/10.1101/2023.01.05.522966v1?med=mas

Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two https://www.biorxiv.org/content/10.1101/2023.01.10.523375v1?med=mas