A cingulate-hippocampal circuit mediates early depressive symptoms in Alzheimer's disease https://www.biorxiv.org/content/10.1101/2023.02.07.527491v1?med=mas
Metabolic modeling of sex-specific tissue predicts mechanisms of differences in toxicological responses https://www.biorxiv.org/content/10.1101/2023.02.07.527430v1?med=mas
Coupling Flux Balance Analysis with Reactive Transport Modeling through Machine Learning for Rapid and Stable Simulation of Microbial Metabolic Switching https://www.biorxiv.org/content/10.1101/2023.02.06.527371v1?med=mas
Unraveling codon usage of Escherichia coli using machine learning https://www.biorxiv.org/content/10.1101/2023.02.07.527422v1?med=mas
Profiling the impact of the promoters on CRISPR-Cas12a system in human cells https://www.biorxiv.org/content/10.1101/2023.02.06.527393v1?med=mas
Curing GFP-itis in Bacteria with Base Editors: Development of a Genome Editing Science Program Implemented with High School Biology Students https://www.biorxiv.org/content/10.1101/2023.02.06.527367v1?med=mas
ADP-ribose-acceptor hydrolase 2 (Arh2) deficiency results in cardiac dysfunction, tumorigenesis, inflammation, and decreased survival https://www.biorxiv.org/content/10.1101/2023.02.07.527494v1?med=mas
A Cas9-fusion proximity-based approach generates an Irak1-Mecp2 tandem duplication mouse model for the study of MeCP2 duplication syndrome. https://www.biorxiv.org/content/10.1101/2023.02.07.527511v1?med=mas
callsync: an R package for alignment and analysis of multi-microphone animal recordings https://www.biorxiv.org/content/10.1101/2023.02.07.527470v1?med=mas
Assessing vector competence of mosquitoes from northeastern France to West Nile virus and Usutu virus https://www.biorxiv.org/content/10.1101/2023.02.07.527438v1?med=mas
Bacterial suppressor-of-copper-sensitivity (Scs) proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions https://www.biorxiv.org/content/10.1101/2023.02.07.527441v1?med=mas
Restricting dietary protein or dietary isoleucine improves metabolic health in aged mice https://www.biorxiv.org/content/10.1101/2023.02.06.527311v1?med=mas
CircSSNN: circRNA-binding site prediction via sequence self-attention neural networks with pre-normalization https://www.biorxiv.org/content/10.1101/2023.02.07.527436v1?med=mas
A fast, robust method for quantitative assessment of collagen fibril architecture from transmission electron micrographs https://www.biorxiv.org/content/10.1101/2023.02.06.527383v1?med=mas
Bio-Heat Transfer and Monte Carlo Measurement of Near-Infrared Transcranial Stimulation of Human Brain https://www.biorxiv.org/content/10.1101/2023.02.07.527427v1?med=mas
H3K27me3 dictates atypical genome-nuclear lamina interactions and allelic asymmetry during early embryogenesis https://www.biorxiv.org/content/10.1101/2023.02.06.527307v1?med=mas
T-toxin virulence genes: unconnected dots in a sea of repeats https://www.biorxiv.org/content/10.1101/2023.02.06.527415v1?med=mas
Cell-specific and shared enhancers control a high-density multi-gene locus active in mammary and salivary glands https://www.biorxiv.org/content/10.1101/2023.02.06.527373v1?med=mas
A new inverse probability of selection weightedCox model to deal with outcome-dependentsampling in survival analysis https://www.biorxiv.org/content/10.1101/2023.02.07.527426v1?med=mas
Widespread natural selection on metabolite levels in humans https://www.biorxiv.org/content/10.1101/2023.02.07.527420v1?med=mas
The non-profit preprint server for the life sciences