bioRxiv @biorxivpreprint@qoto.org

Quantitative classification of energy landscapes inferred from single nanoparticle tracking of membrane receptors inside nanodomains reveals confinement functional and molecular features https://www.biorxiv.org/content/10.1101/2023.02.13.528279v1?med=mas

Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans https://www.biorxiv.org/content/10.1101/2023.02.14.528376v1?med=mas

Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy https://www.biorxiv.org/content/10.1101/2023.02.14.528563v1?med=mas

Inositol pyrophosphate dynamics in yeast reveals control of the PHO starvation program through 1,5-IP8 and the SPX domain of the CDK inhibitor Pho81 https://www.biorxiv.org/content/10.1101/2023.02.14.528555v1?med=mas

Metformin impairs trophoblast metabolism and differentiation in dose dependent manner https://www.biorxiv.org/content/10.1101/2023.02.14.528531v1?med=mas

Physiological reprogramming in vivo mediated by Sox4 pioneer factor activity https://www.biorxiv.org/content/10.1101/2023.02.14.528556v1?med=mas

Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke https://www.biorxiv.org/content/10.1101/2023.02.14.520351v1?med=mas

AMLs harboring DNMT3A-destabilizing variants show increased intratumor DNA methylation heterogeneity at bivalent chromatin domains https://www.biorxiv.org/content/10.1101/2023.02.13.528223v1?med=mas

Structural analyses of 'substrate-pH of activity' pairing observed in Polysaccharide lyases https://www.biorxiv.org/content/10.1101/2023.02.14.528460v1?med=mas

A closer look at high-energy X-ray-induced bubble formation during soft tissue imaging https://www.biorxiv.org/content/10.1101/2023.02.14.528474v1?med=mas

Kinetics and efficacy of antibody drug conjugates in 3D tumour models https://www.biorxiv.org/content/10.1101/2023.02.14.528517v1?med=mas

An intramolecular bivalent degrader glues an intrinsic BRD4-DCAF16 interaction https://www.biorxiv.org/content/10.1101/2023.02.14.528511v1?med=mas

Ancient hybridization leads to the repeated evolution of red flowers across a monkeyflower radiation https://www.biorxiv.org/content/10.1101/2023.02.13.528387v1?med=mas

Self-organizing actin networks drive sequential endocytic protein recruitment and vesicle release on synthetic lipid bilayers https://www.biorxiv.org/content/10.1101/2023.02.14.528546v1?med=mas

Dysregulated miR-3959-3p in response to Lumpy skin disease virus https://www.biorxiv.org/content/10.1101/2023.02.13.528427v1?med=mas

Chemically-induced targeted protein degradation in mycobacteria uncovers antibacterial effects and potentiates antibiotic efficacy https://www.biorxiv.org/content/10.1101/2023.02.14.528552v1?med=mas

Maribacter halichondris sp. nov., isolated from the marine sponge Halichondria panicea https://www.biorxiv.org/content/10.1101/2023.02.14.528435v1?med=mas

Escherichia coli aggregates mediated by native or synthetic adhesins exhibit both core and adhesin-specific transcriptional responses https://www.biorxiv.org/content/10.1101/2023.02.14.528454v1?med=mas

Genomes of the Autonomous Parvovirus Minute Virus of Mice Induce Replication Stress Through RPA Exhaustion https://www.biorxiv.org/content/10.1101/2023.02.13.528428v1?med=mas

Plastic Leachate Exposure Drives Antibiotic Resistance and Virulence in Marine Bacterial Communities https://www.biorxiv.org/content/10.1101/2023.02.13.528379v1?med=mas